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The likelihood ratio (LR) is a commonly used measure for determining the strength of forensic match evidence. When a forensic expert determines a high LR for DNA found at a crime scene matching the DNA profile of a suspect they typically…

Applications · Statistics 2020-09-21 Norman Fenton , Allan Jamieson , Sara Gomes , Martin Neil

The likelihood ratio (LR) measures the relative weight of forensic data regarding two hypotheses. Several levels of uncertainty arise if frequentist methods are chosen for its assessment: the assumed population model only approximates the…

Applications · Statistics 2016-12-26 Giulia Cereda

When presenting forensic evidence, such as a DNA match, experts often use the Likelihood ratio (LR) to explain the impact of evidence . The LR measures the probative value of the evidence with respect to a single hypothesis such as 'DNA…

Applications · Statistics 2021-06-11 Norman Fenton , Martin Neil

Here we present an Italian criminal case that shows how statistical methods can be used to extract information from a series of mixed DNA profiles. The case involves several different individuals and a set of different DNA traces. The case…

Applications · Statistics 2019-08-30 Francesco Dotto , Julia Mortera , Laura Baldasarri , Vincenzo Pascali

The persistent issue of wrongful convictions in the United States emphasizes the need for scrutiny and improvement of the criminal justice system. While statistical methods for the evaluation of forensic evidence, including glass,…

Applications · Statistics 2024-03-25 Xiangyu Xu , Giuseppe Vinci

In forensic DNA calculations of relatedness of individuals and in DNA mixture analyses, two sources of uncertainty are present concerning the allele frequencies used for evaluating genotype probabilities when evaluating likelihoods. They…

Applications · Statistics 2015-10-07 Robert Cowell

The "rare type match problem" is the situation in which the suspect's DNA profile, matching the DNA profile of the crime stain, is not in the database of reference. The evaluation of this match in the light of the two competing hypotheses…

Applications · Statistics 2022-05-30 Giulia Cereda , Richard D. Gill

It is now widely accepted that forensic DNA profiles are rare, so it was a surprise to some people that different people represented in offender databases are being found to have the same profile. In the first place this is just an…

Applications · Statistics 2007-12-18 Bruce S. Weir

DNA databases are widely used in forensic science to identify unknown offenders. When no exact match is found, familial DNA searches can help by identifying first-degree relatives using likelihood ratios. If multiple subpopulations are…

Applications · Statistics 2025-12-08 Monchai Kooakachai , Tiwakorn Chapalee , Chairat Thitiyan , Patsaya Jumnongwut

In both criminal cases and civil cases there is an increasing demand for the analysis of DNA mixtures involving relationships. The goal might be, for example, to identify the contributors to a DNA mixture where the donors may be related, or…

Quantitative Methods · Quantitative Biology 2021-01-12 Peter J. Green , Julia Mortera , Lourdes Prieto

The use of profiling evidence in criminal trials is a longstanding controversy in legal epistemology and evidence law theory. Many scholars, even when they oppose its use at trial, still assume that profiling evidence can be probative of…

Other Statistics · Statistics 2026-03-03 Marcello Di Bello , Nicolò Cangiotti , Michele Loi

Y-chromosomal and mitochondrial DNA profiles have been used as evidence in courts for decades, yet the problem of evaluating the weight of evidence has not been adequately resolved. Both are lineage markers (inherited from just one parent),…

Applications · Statistics 2021-07-08 Mikkel M Andersen , David J Balding

Much of the on-going statistical analysis of DNA sequences is focused on the estimation of characteristics of coding and non-coding regions that would possibly allow discrimination of these regions. In the current approach, we concentrate…

Genomics · Quantitative Biology 2009-11-10 D. Kugiumtzis , A. Provata

We present methods for inference about relationships between contributors to a DNA mixture and other individuals of known genotype: a basic example would be testing whether a contributor to a mixture is the father of a child of known…

Applications · Statistics 2017-01-30 Peter J. Green , Julia Mortera

The evaluation of a match between the DNA profile of a stain found on a crime scene and that of a suspect (previously identified) involves the use of the unknown parameter $p=(p_1, p_2, ...)$, (the ordered vector which represents the…

Applications · Statistics 2015-09-21 Giulia Cereda

In observational studies of discrimination, the most common statistical approaches consider either the rate at which decisions are made (benchmark tests) or the success rate of those decisions (outcome tests). Both tests, however, have…

Applications · Statistics 2025-03-07 Johann D. Gaebler , Sharad Goel

This paper presents a probabilistic approach for DNA sequence analysis. A DNA sequence consists of an arrangement of the four nucleotides A, C, T and G and different representation schemes are presented according to a probability measure…

Quantitative Methods · Quantitative Biology 2010-02-12 Amrita Priyam , B. M. Karan , G. Sahoo

There is active debate over whether to consider patient race and ethnicity when estimating disease risk. By accounting for race and ethnicity, it is possible to improve the accuracy of risk predictions, but there is concern that their use…

Applications · Statistics 2023-06-21 Madison Coots , Soroush Saghafian , David Kent , Sharad Goel

The likelihood ratio (LR) is largely used to evaluate the relative weight of forensic data regarding two hypotheses and for its assessment Bayesian methods are widespread in the forensic field. However, the Bayesian `recipe' for the LR…

Applications · Statistics 2016-04-14 Giulia Cereda

Familial Searching is the process of searching in a DNA database for relatives of a certain individual. It is well known that in order to evaluate the genetic evidence in favour of a certain given form of relatedness between two…

Applications · Statistics 2015-03-20 Klaas Slooten , Ronald Meester
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