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Mutation rate variation across loci is well known to cause difficulties, notably identifiability issues, in the reconstruction of evolutionary trees from molecular sequences. Here we introduce a new approach for estimating general…

Probability · Mathematics 2011-09-30 Elchanan Mossel , Sebastien Roch

A probability model is presented for the dynamics of mutation-selection balance in a haploid infinite-population infinite-sites setting sufficiently general to cover mutation-driven changes in full age-specific demographic schedules. The…

Populations and Evolution · Quantitative Biology 2007-05-23 David Steinsaltz , Steven N. Evans , Kenneth W. Wachter

Markov models of character substitution on phylogenies form the foundation of phylogenetic inference frameworks. Early models made the simplifying assumption that the substitution process is homogeneous over time and across sites in the…

Populations and Evolution · Quantitative Biology 2019-06-13 Guy Baele , Mandev S. Gill , Philippe Lemey , Marc A. Suchard

The algebraic properties of flattenings and subflattenings provide direct methods for identifying edges in the true phylogeny -- and by extension the complete tree -- using pattern counts from a sequence alignment. The relatively small…

Populations and Evolution · Quantitative Biology 2022-05-06 Joshua Stevenson , Barbara Holland , Michael Charleston , Jeremy Sumner

Within the field of phylogenetics there is great interest in distance measures to quantify the dissimilarity of two trees. Recently, a new distance measure has been proposed: the Maximum Parsimony (MP) distance. This is based on the…

Populations and Evolution · Quantitative Biology 2015-01-20 Steven Kelk , Mareike Fischer

We provide a new approach for proving the indistinguishability of connected components of random one-or-two-ended oriented forests on unimodular random graphs. In particular, this approach leads to a new and simpler proof for the wired…

Probability · Mathematics 2026-05-18 Francois Baccelli , Ali Khezeli

Scientific explanation often requires inferring maximally predictive features from a given data set. Unfortunately, the collection of minimal maximally predictive features for most stochastic processes is uncountably infinite. In such…

Statistical Mechanics · Physics 2017-05-31 Sarah E. Marzen , James P. Crutchfield

This paper considers a Markov-modulated duplication-deletion random graph where at each time instant, one node can either join or leave the network; the probabilities of joining or leaving evolve according to the realization of a finite…

Information Theory · Computer Science 2013-03-04 Maziyar Hamdi , Vikram Krishnamurthy , George Yin

The deterministic selection-recombination equation describes the evolution of the genetic type composition of a population under selection and recombination in a law of large numbers regime. So far, an explicit solution has seemed out of…

Probability · Mathematics 2023-04-26 Ellen Baake , Frederic Alberti

We introduce Generator Matching, a modality-agnostic framework for generative modeling using arbitrary Markov processes. Generators characterize the infinitesimal evolution of a Markov process, which we leverage for generative modeling in a…

Machine Learning · Computer Science 2025-02-28 Peter Holderrieth , Marton Havasi , Jason Yim , Neta Shaul , Itai Gat , Tommi Jaakkola , Brian Karrer , Ricky T. Q. Chen , Yaron Lipman

The goal of this work is to decompose random populations with a genealogy in subfamilies of a given degree of kinship and to obtain a notion of infinitely divisible genealogies. We model the genealogical structure of a population by…

Probability · Mathematics 2019-04-09 Patrick Gloede , Andreas Greven , Thomas Rippl

Ordered, linear, and other substructural type systems allow us to expose deep properties of programs at the syntactic level of types. In this paper, we develop a family of unary logical relations that allow us to prove consequences of…

Logic in Computer Science · Computer Science 2025-03-06 C. B. Aberlé , Chris Martens , Frank Pfenning

The marginal likelihood of a model is a key quantity for assessing the evidence provided by the data in support of a model. The marginal likelihood is the normalizing constant for the posterior density, obtained by integrating the product…

Populations and Evolution · Quantitative Biology 2018-11-30 Mathieu Fourment , Andrew F. Magee , Chris Whidden , Arman Bilge , Frederick A. Matsen , Vladimir N. Minin

We discuss a notion of convergence for binary trees that is based on subtree sizes. In analogy to recent developments in the theory of graphs, posets and permutations we investigate some general aspects of the topology, such as a…

Combinatorics · Mathematics 2024-02-14 Rudolf Grübel

Various and ubiquitous information systems are being used in monitoring, exchanging, and collecting information. These systems are generating massive amount of event sequence logs that may help us understand underlying phenomenon. By…

Machine Learning · Statistics 2018-07-13 Yihuang Kang , Vladimir Zadorozhny

Submodularity is a key property in discrete optimization. Submodularity has been widely used for analyzing the greedy algorithm to give performance bounds and providing insight into the construction of valid inequalities for mixed-integer…

Optimization and Control · Mathematics 2022-05-24 Temitayo Ajayi , Taewoo Lee , Andrew Schaefer

In this article we propose a novel method to estimate the frequency distribution of linguistic variables while controlling for statistical non-independence due to shared ancestry. Unlike previous approaches, our technique uses all available…

Populations and Evolution · Quantitative Biology 2021-03-22 Gerhard Jäger , Johannes Wahle

We apply the theory of markov random fields on trees to derive a phase transition in the number of samples needed in order to reconstruct phylogenies. We consider the Cavender-Farris-Neyman model of evolution on trees, where all the inner…

Probability · Mathematics 2007-05-23 Elchanan Mossel

We consider random binary trees that appear as the output of certain standard algorithms for sorting and searching if the input is random. We introduce the subtree size metric on search trees and show that the resulting metric spaces…

Probability · Mathematics 2014-05-06 Rudolf Grübel

We introduce the notion of semi-characteristic polynomial for a semi-linear map of a finite- dimensional vector space over a field of characteristic p. This polynomial has some properties in common with the classical characteristic…

Representation Theory · Mathematics 2011-05-23 Jérémy Le Borgne
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