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Continuum models for the spatial dynamics of growing cell populations have been widely used to investigate the mechanisms underpinning tissue development and tumour invasion. These models consist of nonlinear partial differential equations…

Tissues and Organs · Quantitative Biology 2019-07-15 Mark AJ Chaplain , Tommaso Lorenzi , Fiona R Macfarlane

In this paper we study disease spread over a randomly switched network, which is modeled by a stochastic switched differential equation based on the so called $N$-intertwined model for disease spread over static networks. Assuming that all…

Systems and Control · Computer Science 2016-11-04 Masaki Ogura , Victor M. Preciado

The spreading of bacterial populations is central to processes in agriculture, the environment, and medicine. However, existing models of spreading typically focus on cells in unconfined settings--despite the fact that many bacteria inhabit…

Populations and Evolution · Quantitative Biology 2022-06-07 Daniel B. Amchin , Jenna A. Ott , Tapomoy Bhattacharjee , Sujit S. Datta

Spatial patterning can be crucially important for understanding the behavior of interacting populations. Here we investigate a simple model of parasite and host populations in which parasites are random walkers that must come into contact…

Populations and Evolution · Quantitative Biology 2015-09-07 J. J. Dong , B. Skinner , N. Breecher , B. Schmittmann , R. K. P. Zia

In this article, we study a branching random walk in an environment which depends on the time. This time-inhomogeneous environment consists of a sequence of macroscopic time intervals, in each of which the law of reproduction remains…

Probability · Mathematics 2017-06-13 Bastien Mallein

We study a stochastic epidemic model consisting of elements (organisms in a community or cells in tissue) with fixed positions, in which damage or disease is transmitted by diffusing agents ("signals") emitted by infected individuals. The…

Populations and Evolution · Quantitative Biology 2015-06-05 Fernando P. Faria , Ronald Dickman

We consider a subcritical branching process in an i.i.d. random environment, in which one immigrant arrives at each generation. We consider the event $% \mathcal{A}_{i}(n)$ that all individuals alive at time $n$ are offspring of the…

Probability · Mathematics 2020-09-09 E. E. Dyakonova , V. A. Vatutin

We consider a branching random walk in a random space-time environment of disasters where each particle is killed when meeting a disaster. This extends the model of the "random walk in a disastrous random environment" introduced by [15]. We…

Probability · Mathematics 2017-09-13 Nina Gantert , Stefan Junk

Infectious pathogens often propagate by superspreading, which focusses onward transmission on disproportionately few infected individuals. At the same time, infector-infectee pairs tend to have more similar transmission potentials than…

Populations and Evolution · Quantitative Biology 2025-09-22 Noah Silva de Leonardi , Benjamin D. Dalziel

We investigate recurrence and transience of Branching Markov Chains (BMC) in discrete time. Branching Markov Chains are clouds of particles which move (according to an irreducible underlying Markov Chain) and produce offspring…

Probability · Mathematics 2016-09-07 Nina Gantert , Sebastian Mueller

We consider multiple diseases spreading in a static Configuration Model network. We make standard assumptions that infection transmits from neighbor to neighbor at a disease-specific rate and infected individuals recover at a…

Populations and Evolution · Quantitative Biology 2015-06-11 Joel C. Miller

Language spreading is a complex mechanism that involves issues like culture, economics, migration, population etc. In this paper, we propose a set of methods to model the dynamics of the spreading system. To model the randomness of language…

Computation and Language · Computer Science 2018-02-27 XingYu Fu , ZiYi Yang , XiuWen Duan

We consider a class of biologically-motivated stochastic processes in which a unicellular organism divides its resources (volume or damaged proteins, in particular) symmetrically or asymmetrically between its progeny. Assuming the final…

Quantitative Methods · Quantitative Biology 2016-07-20 Andrew Marantan , Ariel Amir

We consider the evolution of populations under the joint action of mutation and differential reproduction, or selection. The population is modelled as a finite-type Markov branching process in continuous time, and the associated…

Populations and Evolution · Quantitative Biology 2009-02-23 Ellen Baake , Hans-Otto Georgii

Stochastic processes can model many emerging phenomena on networks, like the spread of computer viruses, rumors, or infectious diseases. Understanding the dynamics of such stochastic spreading processes is therefore of fundamental interest.…

Social and Information Networks · Computer Science 2019-01-07 Gerrit Großmann , Verena Wolf

We model the growth of a cell population by a piecewise deterministic Markov branching tree. Each cell splits into two offsprings at a division rate $B(x)$ that depends on its size $x$. The size of each cell grows exponentially in time, at…

Probability · Mathematics 2015-05-29 Marie Doumic , Marc Hoffmann , Nathalie Krell , Lydia Robert

The spatiotemporal coordination and regulation of cell proliferation is fundamental in many aspects of development and tissue maintenance. Cells have the ability to adapt their division rates in response to mechanical constraints, yet we do…

Quantitative Methods · Quantitative Biology 2024-04-25 Carles Falcó , Daniel J. Cohen , José A. Carrillo , Ruth E. Baker

We consider processes that coincide with a given diffusion process except on the boundaries of a finite collection of domains. The behavior on each of the boundaries is asymmetric: the process is much more likely to enter the interior of…

Probability · Mathematics 2020-03-18 Mark Freidlin , Leonid Koralov

Understanding the rules underlying organismal development is a major unsolved problem in biology. Each cell in a developing organism responds to signals in its local environment by dividing, excreting, consuming, or reorganizing, yet how…

Cell Behavior · Quantitative Biology 2025-08-20 Ramya Deshpande , Francesco Mottes , Ariana-Dalia Vlad , Michael P. Brenner , Alma dal Co

We study the dynamics of secondary infections on networks, in which only the individuals currently carrying a certain primary infection are susceptible to the secondary infection. In the limit of large sparse networks, the model is mapped…

Probability · Mathematics 2018-05-23 Sam Moore , Peter Mörters , Tim Rogers