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We analytically derive mean-field models for all-to-all coupled networks of heterogeneous, adapting, two-dimensional integrate and fire neurons. The class of models we consider includes the Izhikevich, adaptive exponential, and quartic…

Neurons and Cognition · Quantitative Biology 2013-09-20 Wilten Nicola , Sue Ann Campbell

In physics we often use very simple models to describe systems with many degrees of freedom, but it is not clear why or how this success can be transferred to the more complex biological context. We consider models for the joint…

Neurons and Cognition · Quantitative Biology 2024-12-06 Luisa Ramirez , William Bialek , Stephanie E. Palmer , David J. Schwab

Nonlinear dynamics system identification is crucial for circuit emulation. Traditional continuous-time domain modeling approaches have limitations in fitting capability and computational efficiency when used for modeling circuit IPs and…

Machine Learning · Computer Science 2025-06-18 Zenghui Chang , Yang Zhang , Hu Tan , Hong Cai Chen

The neural Hawkes process (Mei & Eisner, 2017) is a generative model of irregularly spaced sequences of discrete events. To handle complex domains with many event types, Mei et al. (2020a) further consider a setting in which each event in…

Machine Learning · Computer Science 2022-05-09 Chenghao Yang , Hongyuan Mei , Jason Eisner

In spiking neural networks, neuron dynamics are described by the biologically realistic integrate-and-fire model that captures membrane potential accumulation and above-threshold firing behaviors. Among the hardware implementations of…

Neural and Evolutionary Computing · Computer Science 2024-05-24 Can Cui1 , Sam Liu , Jaesuk Kwon , Jean Anne C. Incorvia

We address the problem of simulation and parameter inference for chemical reaction networks described by the chemical Langevin equation, a stochastic differential equation (SDE) representation of the dynamics of the chemical species. This…

Methodology · Statistics 2025-08-18 Petar Jovanovski , Andrew Golightly , Umberto Picchini , Massimiliano Tamborrino

There has been a long-standing controversy whether information in neuronal networks is carried by the firing rate code or by the firing temporal code. The current status of the rivalry between the two codes is briefly reviewed with the…

Disordered Systems and Neural Networks · Physics 2007-05-23 Hideo Hasegawa

The pairwise maximum entropy model, also known as the Ising model, has been widely used to analyze the collective activity of neurons. However, controversy persists in the literature about seemingly inconsistent findings, whose significance…

Disordered Systems and Neural Networks · Physics 2019-03-13 Cristian Zanoci , Nima Dehghani , Max Tegmark

The Nonlinear Noisy Leaky Integrate and Fire (NNLIF) model is widely used to describe the dynamics of neural networks after a diffusive approximation of the mean-field limit of a stochastic differential equation system. When the total…

Analysis of PDEs · Mathematics 2018-06-07 María J. Cáceres , Pierre Roux , Delphine Salort , Ricarda Schneider

Training a model to detect patterns of interrelated events that form situations of interest can be a complex problem: such situations tend to be uncommon, and only sparse data is available. We propose a hybrid neuro-symbolic architecture…

Understanding the non-equilibrium dynamics of extended quantum systems after the trigger of a sudden, global perturbation (quench) represents a daunting challenge, especially in the presence of interactions. The main difficulties stem from…

Strongly Correlated Electrons · Physics 2009-11-13 Alexandre Faribault , Pasquale Calabrese , Jean-Sebastien Caux

This work integrates the physics-informed neural network (PINN) approach into the neural quantum state framework to simulate open quantum system dynamics, to circumvent the computationally expensive time-dependent variational principle…

Quantum Physics · Physics 2026-04-30 Long Cao , Liwei Ge , Daochi Zhang , Yao Wang , Rui-Xue Xu , YiJing Yan , Xiao Zheng

Manufacturing-viable neuromorphic chips require novel computer architectures to achieve the massively parallel and efficient information processing the brain supports so effortlessly. Emerging event-based architectures are making this dream…

Hardware Architecture · Computer Science 2023-01-25 Lennart Bamberg , Arash Pourtaherian , Luc Waeijen , Anupam Chahar , Orlando Moreira

We show how to apply the absorbing Markov chain Monte Carlo algorithm of Novotny to simulate kinetically constrained models of glasses. We consider in detail one-spin facilitated models, such as the East model and its generalizations to…

Statistical Mechanics · Physics 2009-11-11 Douglas J. Ashton , Lester O. Hedges , Juan P. Garrahan

We present a physics-based neural network framework for the discovery of constitutive models in fully coupled thermomechanics. In contrast to classical formulations based on the Helmholtz energy, we adopt the internal energy and a…

Computational Engineering, Finance, and Science · Computer Science 2026-05-25 Hagen Holthusen , Paul Steinmann , Ellen Kuhl

We introduce a two-phase quadratic integrate-and-fire (QIF) neuron whose membrane potential evolves according to two alternating Riccati equations within finite bounds. This simple extension removes the unphysical voltage divergence of the…

Neurons and Cognition · Quantitative Biology 2026-03-05 Rok Cestnik

For handling intercurrent events in clinical trials, one of the strategies outlined in the ICH E9(R1) addendum targets the hypothetical scenario of non-occurrence of the intercurrent event. While this strategy is often implemented by…

Methodology · Statistics 2024-09-18 Florian Lasch , Lorenzo Guizzaro , Wen Wei Loh

Multiphysics problems that are characterized by complex interactions among fluid dynamics, heat transfer, structural mechanics, and electromagnetics, are inherently challenging due to their coupled nature. While experimental data on certain…

Machine Learning · Computer Science 2024-10-16 Khemraj Shukla , Zongren Zou , Chi Hin Chan , Additi Pandey , Zhicheng Wang , George Em Karniadakis

To understand possible strategies of temporal spike coding in the central nervous system, we study functional neuromimetic models of visual processing for static images. We will first present the retinal model which was introduced by Van…

Neurons and Cognition · Quantitative Biology 2007-05-23 Laurent Perrinet , Manuel Samuelides , Simon Thorpe

The neural dynamics generating sensory, motor, and cognitive functions are commonly understood through field theories for neural population activity. Classic neural field theories are derived from highly simplified models of individual…

Neurons and Cognition · Quantitative Biology 2023-11-21 Gabriel Koch Ocker