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What can we learn from the collective dynamics of a complex network about its interaction topology? Taking the perspective from nonlinear dynamics, we briefly review recent progress on how to infer structural connectivity (direct…

Adaptation and Self-Organizing Systems · Physics 2014-08-14 Marc Timme , Jose Casadiego

To study implementations and optimisations of interaction net systems we propose a calculus to allow us to reason about nets, a concrete data-structure that is in close correspondence with the calculus, and a low-level language to create…

Logic in Computer Science · Computer Science 2015-05-28 Abubakar Hassan , Ian Mackie , Shinya Sato

The information systems have been extremely useful in managing businesses, enterprises, and public institutions such as government departments. But current challenges are increasingly about managing ecosystems. Ecosystem is a useful…

Computers and Society · Computer Science 2025-11-07 Shreekanth M Prabhu , Natarajan Subramanyam

Inferring topological characteristics of complex networks from observed data is critical to understand the dynamical behavior of networked systems, ranging from the Internet and the World Wide Web to biological networks and social networks.…

Multiagent Systems · Computer Science 2020-05-13 Chunheng Jiang , Jianxi Gao , Malik Magdon-Ismail

Causal inference has traditionally focused on interventions at the unit level. In many applications, however, the central question concerns the causal effects of connections between units, such as transportation links, social relationships,…

Methodology · Statistics 2026-01-13 Shuli Chen , Jie Hu , Zhichao Jiang

Extracting understanding from the growing ``sea'' of biological and socio-economic data is one of the most pressing scientific challenges facing us. Here, we introduce and validate an unsupervised method that is able to accurately extract…

Physics and Society · Physics 2009-11-13 M. Sales-Pardo , R. Guimera , A. Moreira , L. Amaral

Social networks contain implicit knowledge that can be used to infer hierarchical relations that are not explicitly present in the available data. Interaction patterns are typically affected by users' social relations. We present an…

Social and Information Networks · Computer Science 2017-01-25 Hend Kareem , Lars Asker , Panagiotis Papapetrou

In the work two ways of evolutionary interpretation of entropy model for correspondence matrix calculation are proposed. Both approaches based on the stochastic chemical kinetic evolution under the detailed balance condition. The first…

Optimization and Control · Mathematics 2020-03-30 Alexander Gasnikov , Evgenia Gasnikova , Mikhail Mendel , Ksenya Chepurchenko

Understanding the dynamics of spatially extended systems represents a challenge in diverse scientific disciplines, ranging from physics and mathematics to the earth and climate sciences or the neurosciences. This challenge has stimulated…

Data Analysis, Statistics and Probability · Physics 2012-08-06 S. Bialonski

Network datasets appear across a wide range of scientific fields, including biology, physics, and the social sciences. To enable data-driven discoveries from these networks, statistical inference techniques like estimation and hypothesis…

Methodology · Statistics 2026-02-19 Arpan Kumar , Minh Tang , Srijan Sengupta

Design of experiments is a branch of statistics that aims to identify efficient procedures for planning experiments in order to optimize knowledge discovery. Network inference is a subfield of systems biology devoted to the identification…

Molecular Networks · Quantitative Biology 2019-07-12 Reinhard Laubenbacher , Brandilyn Stigler

One of the most interesting, difficult, and potentially useful topics in computational biology is the inference of gene regulatory networks (GRNs) from expression data. Although researchers have been working on this topic for more than a…

Molecular Networks · Quantitative Biology 2019-11-12 Michael M. Saint-Antoine , Abhyudai Singh

Networks pervade many disciplines of science for analyzing complex systems with interacting components. In particular, this concept is commonly used to model interactions between genes and identify closely associated genes forming…

Methodology · Statistics 2015-06-02 Y. X. Rachel Wang , Keni Jiang , Lewis J. Feldman , Peter J. Bickel , Haiyan Huang

A detailed algorithmic explanation is required for how a network of chemical reactions can generate the sophisticated behavior displayed by living cells. Though several previous works have shown that reaction networks are computationally…

Emerging Technologies · Computer Science 2018-04-25 Muppirala Viswa Virinchi , Abhishek Behera , Manoj Gopalkrishnan

Gene and protein networks are very important to model complex large-scale systems in molecular biology. Inferring or reverseengineering such networks can be defined as the process of identifying gene/protein interactions from experimental…

Machine Learning · Computer Science 2017-03-10 Stefano Beretta , Mauro Castelli , Ivo Goncalves , Ivan Merelli , Daniele Ramazzotti

Data-driven dynamic models of cell biology can be used to predict cell response to unseen perturbations. Recent work (CellBox) had demonstrated the derivation of interpretable models with explicit interaction terms, in which the parameters…

Molecular Networks · Quantitative Biology 2021-04-15 Weiqi Ji , Bo Yuan , Ciyue Shen , Aviv Regev , Chris Sander , Sili Deng

We study monotone ecological inference, a partial identification approach to ecological inference. The approach exploits information about one or both of the following conditional associations: (1) outcome differences between groups within…

Methodology · Statistics 2025-04-22 Hadi Elzayn , Jacob Goldin , Cameron Guage , Daniel E. Ho , Claire Morton

We consider causal inference in the presence of unobserved confounding. We study the case where a proxy is available for the unobserved confounding in the form of a network connecting the units. For example, the link structure of a social…

Machine Learning · Statistics 2019-06-03 Victor Veitch , Yixin Wang , David M. Blei

Competitive interactions represent one of the driving forces behind evolution and natural selection in biological and sociological systems. For example, animals in an ecosystem may vie for food or mates; in a market economy, firms may…

Physics and Society · Physics 2013-07-03 Jacobo Aguirre , David Papo , Javier M. Buldú

Phylogenetic networks model reticulate evolutionary histories. The last two decades have seen an increased interest in establishing mathematical results and developing computational methods for inferring and analyzing these networks. A…

Populations and Evolution · Quantitative Biology 2016-06-24 Jiafan Zhu , Yun Yu , Luay Nakhleh