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Since the seminal work of Powell, the relationships between the population growth rate, the probability distributions of generation time, and the distribution of cell age have been known for the bacterial population in a steady state of…

Biological Physics · Physics 2023-06-02 Jakub Jędrak , Marcin Rubin , Anna Ochab-Marcinek

We consider a two-node fluid network with batch arrivals of random size having a heavy-tailed distribution. We are interested in the tail asymptotics for the stationary distribution of a two-dimensional queue-length process. The tail…

Probability · Mathematics 2016-11-25 Sergey Foss , Masakiyo Miyazawa

In traditional extreme value analysis, the bulk of the data is ignored, and only the tails of the distribution are used for inference. Extreme observations are specified as values that exceed a threshold or as maximum values over distinct…

Applications · Statistics 2021-10-20 Mitchell Krock , Julie Bessac , Michael L. Stein , Adam H. Monahan

Exponential tail bounds for sums play an important role in statistics, but the example of the $t$-statistic shows that the exponential tail decay may be lost when population parameters need to be estimated from the data. However, it turns…

Statistics Theory · Mathematics 2022-03-22 Guenther Walther

Motivated by seminal paper of Kozlov et al.(1975) we consider in this paper a branching process with a geometric offspring distribution parametrized by random success probability $A$ and immigration equals $1$ in each generation. In…

Probability · Mathematics 2019-07-31 Ayan Bhattacharya , Zbigniew Palmowski

In sustained growth with random dynamics stationary distributions can exist without detailed balance. This suggests thermodynamical behavior in fast growing complex systems. In order to model such phenomena we apply both a discrete and a…

Statistical Mechanics · Physics 2017-03-22 Tamás Biró , Zoltán Néda

We consider a family of multivariate distributions with heavy-tailed margins and the type I elliptical dependence structure. This class of risks is common in finance, insurance, environmental and biostatistic applications. We obtain the…

Statistics Theory · Mathematics 2024-05-01 Kai Wang , Chengxiu Ling

We construct a pathwise formulation of a growing population of cells, based on two different samplings of lineages within the population, namely the forward and backward samplings. We show that a general symmetry relation, called…

Populations and Evolution · Quantitative Biology 2021-11-03 Arthur Genthon , David Lacoste

We introduce and discuss spatially homogeneous Maxwell-type models of the nonlinear Boltzmann equation undergoing binary collisions with a random component. The random contribution to collisions is such that the usual collisional invariants…

Analysis of PDEs · Mathematics 2008-01-18 José Antonio Carrillo , Stéphane Cordier , Giuseppe Toscani

Stochastic models, based on random processes, may lead to power law distributions, which provide long range correlations. The observation of power law behavior and the presence of long range correlations in biological systems has been…

Statistical Mechanics · Physics 2008-03-26 Thomas Oikonomou

Observation of phenotypic diversity in a population of genetically identical cells is often linked to the stochastic nature of chemical reactions involved in gene regulatory networks. We investigate the distribution of population averaged…

Molecular Networks · Quantitative Biology 2015-06-18 Bhaswati Bhattacharyya , Ziya Kalay

Extreme events and the heavy tail distributions driven by them are ubiquitous in various scientific, engineering and financial research. They are typically associated with stochastic instability caused by hidden unresolved processes.…

Probability · Mathematics 2019-05-22 Andrew J. Majda , Xin T. Tong

Solving population balance equations, we derive analytical steady-state cell size distributions for single-lineage experiments, such as the mother machine. These experiments are fundamentally different from batch cultures where populations…

Populations and Evolution · Quantitative Biology 2023-09-13 Arthur Genthon

The total number of fatalities of an epidemic outbreak is a dramatic but extremely informative quantity. Knowledge of the statistics of this quantity allows the calculation of the mean total number of fatalities conditioned to the fact that…

Physics and Society · Physics 2024-03-06 Alvaro Corral

We consider phase-type scale mixture distributions which correspond to distributions of a product of two independent random variables: a phase-type random variable $Y$ and a nonnegative but otherwise arbitrary random variable $S$ called the…

Probability · Mathematics 2017-05-16 Leonardo Rojas-Nandayapa , Wangyue Xie

Let $X_{1},\ldots ,X_{n}$ be $n$ real-valued dependent random variables. With motivation from Mitra and Resnick (2009), we derive the tail asymptotic expansion for the weighted sum of order statistics $X_{1:n}\leq \cdots \leq X_{n:n}$ of…

Probability · Mathematics 2014-08-07 Enkelejd Hashorva , Jinzhi Li

In this Note, we describe the stationary equilibria and the asymptotic behaviour of an heterogeneous logistic reaction-diffusion equation under the influence of autonomous or time-periodic forcing terms. We show that the study of the…

Analysis of PDEs · Mathematics 2010-06-15 Mickaël D. Chekroun , Lionel Roques

At high levels, the asymptotic distribution of a stationary, regularly varying Markov chain is conveniently given by its tail process. The latter takes the form of a geometric random walk, the increment distribution depending on the sign of…

Methodology · Statistics 2014-12-11 Holger Drees , Johan Segers , Michał Warchoł

In many situations, the gene expression signature is a unique marker of the biological state. We study the modification of the gene expression distribution function when the biological state of a system experiences a change. This change may…

Quantitative Methods · Quantitative Biology 2022-05-19 Augusto Gonzalez , Joan Nieves , Maria Luisa Bringas Vega , Pedro Valdes Sosa

How are granular details of stochastic growth and division of individual cells reflected in smooth deterministic growth of population numbers? We provide an integrated, multiscale perspective of microbial growth dynamics by formulating a…