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Explosive growth in the amount of genomic data is matched by increasing power of consumer-grade computers. Even applications that require powerful servers can be quickly tested on desktop or laptop machines if we can generate representative…

Genomics · Quantitative Biology 2017-11-20 Anthony J. Greenberg

Gradient descent algorithms are widely used in machine learning. In order to deal with huge volume of data, we consider the implementation of gradient descent algorithms in a distributed computing setting where multiple workers compute the…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-29 Haozhao Wang , Song Guo , Bin Tang , Ruixuan Li , Chengjie Li

Objective: Modelling the associations from high-throughput experimental molecular data has provided unprecedented insights into biological pathways and signalling mechanisms. Graphical models and networks have especially proven to be useful…

Machine Learning · Statistics 2013-04-24 Marco Scutari , Radhakrishnan Nagarajan

Change point detection has become an important part of the analysis of the single-particle tracking data, as it allows one to identify moments, in which the motion patterns of observed particles undergo significant changes. The segmentation…

Quantitative Methods · Quantitative Biology 2025-06-23 Jakub Malinowski , Marcin Kostrzewa , Michał Balcerek , Weronika Tomczuk , Janusz Szwabiński

In big data analysis, a simple task such as linear regression can become very challenging as the variable dimension $p$ grows. As a result, variable screening is inevitable in many scientific studies. In recent years, randomized algorithms…

Methodology · Statistics 2019-02-13 Yu-Hsiang Cheng , Tzee-Ming Huang , Su-Yun Huang

Various methods have been developed to analyze the association between organisms and their genomic sequences. Among them, sequence alignment is the most frequently used for comparative analysis of biological genomes. However, the…

Quantitative Methods · Quantitative Biology 2020-10-27 Yong Joon Song , Dong Jin Ji , Hye In Seo , Gyu Bum Han , Dong Ho Cho

Federated learning is an emerging research paradigm for enabling collaboratively training deep learning models without sharing patient data. However, the data from different institutions are usually heterogeneous across institutions, which…

Machine Learning · Computer Science 2022-04-12 Miao Zhang , Liangqiong Qu , Praveer Singh , Jayashree Kalpathy-Cramer , Daniel L. Rubin

Deep learning has revolutionized many industries by enabling models to automatically learn complex patterns from raw data, reducing dependence on manual feature engineering. However, deep learning algorithms are sensitive to input data, and…

Machine Learning · Computer Science 2025-07-21 Mert Sehri , Zehui Hua , Francisco de Assis Boldt , Patrick Dumond

Recently, several image segmentation methods that welcome and leverage different types of user assistance have been developed. In these methods, the user inputs can be provided by drawing bounding boxes over image objects, drawing scribbles…

Computer Vision and Pattern Recognition · Computer Science 2022-04-06 Huseyin Afser

The accurate segmentation and tracking of cells in microscopy image sequences is an important task in biomedical research, e.g., for studying the development of tissues, organs or entire organisms. However, the segmentation of touching…

Computer Vision and Pattern Recognition · Computer Science 2020-12-10 Tim Scherr , Katharina Löffler , Moritz Böhland , Ralf Mikut

The rapid advancements in artificial intelligence (AI) have revolutionized smart healthcare, driving innovations in wearable technologies, continuous monitoring devices, and intelligent diagnostic systems. However, security, explainability,…

Machine Learning · Computer Science 2024-10-02 Prasenjit Maji , Amit Kumar Mondal , Hemanta Kumar Mondal , Saraju P. Mohanty

In many areas of science multiple sets of data are collected pertaining to the same system. Examples are food products which are characterized by different sets of variables, bio-processes which are on-line sampled with different…

Chromosome classification is an important but difficult and tedious task in karyotyping. Previous methods only classify manually segmented single chromosome, which is far from clinical practice. In this work, we propose a detection based…

Computer Vision and Pattern Recognition · Computer Science 2021-08-18 Chunlong Luo , Tianqi Yu , Yufan Luo , Manqing Wang , Fuhai Yu , Yinhao Li , Chan Tian , Jie Qiao , Li Xiao

The problem of learning the structure of a high dimensional graphical model from data has received considerable attention in recent years. In many applications such as sensor networks and proteomics it is often expensive to obtain samples…

Machine Learning · Statistics 2016-04-08 Gautam Dasarathy , Aarti Singh , Maria-Florina Balcan , Jong Hyuk Park

A critical challenge in single-cell RNA sequencing (scRNA-seq) integration is resolving the tension between eliminating batch effects and maintaining biological fidelity. While recent evidence indicates that batch effects manifest…

Machine Learning · Computer Science 2026-05-19 Xichen Yan , Zelin Zang , Changxi Chi , Jingbo Zhou , Chang Yu , Jinlin Wu , Shenghui Cheng , Fuji Yang , Jiebo Luo , Zhen Lei , Stan Z. Li

Pathological structures in medical images are typically deviations from the expected anatomy of a patient. While clinicians consider this interplay between anatomy and pathology, recent deep learning algorithms specialize in recognizing…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Alexander Jaus , Constantin Seibold , Simon Reiß , Lukas Heine , Anton Schily , Moon Kim , Fin Hendrik Bahnsen , Ken Herrmann , Rainer Stiefelhagen , Jens Kleesiek

Fast data synchronization in wireless ad hoc networks is a challenging and critical problem. It is fundamental for efficient information fusion, control and decision in distributed systems. Previously, distributed data synchronization was…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-09-20 Die Hu , Xuejun Zhu , Min Gong , Shaoshi Yang

Motivation: Alignment-free distance and similarity functions (AF functions, for short) are a well established alternative to two and multiple sequence alignments for many genomic, metagenomic and epigenomic tasks. Due to data-intensive…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-10-26 Umberto Ferraro Petrillo , Francesco Palini , Giuseppe Cattaneo , Raffaele Giancarlo

We propose a cell segmentation method for analyzing images of densely clustered cells. The method combines the strengths of marker-controlled watershed transformation and a convolutional neural network (CNN). We demonstrate the method…

Image and Video Processing · Electrical Eng. & Systems 2020-04-06 Filip Lux , Petr Matula

Cancer is a leading cause of death worldwide, necessitating advancements in early detection and treatment technologies. In this paper, we present a novel and highly efficient melanoma detection framework that synergistically combines the…

Image and Video Processing · Electrical Eng. & Systems 2024-08-05 Peng Zhang , Divya Chaudhary