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The statistical shape analysis called Procrustes analysis minimizes the distance between matrices by similarity transformations. The method returns a set of optimal orthogonal matrices, which project each matrix into a common space. This…

Applications · Statistics 2023-01-18 Angela Andreella , Riccardo De Santis , Anna Vesely , Livio Finos

Understanding propagation structures in graph diffusion processes, such as epidemic spread or misinformation diffusion, is a fundamental yet challenging problem. While existing methods primarily focus on source localization, they cannot…

Social and Information Networks · Computer Science 2025-03-04 Zeeshan Memon , Chen Ling , Ruochen Kong , Vishwanath Seshagiri , Andreas Zufle , Liang Zhao

A wide range of applications and research has been done with genome-scale metabolic models. In this work we describe a methodology for comparing metabolic networks constructed from genome-scale metabolic models and how to apply this…

Molecular Networks · Quantitative Biology 2026-02-06 D. Gamermann , A. Montagud , J. A. Conejero , P. F. de Córdoba , J. F. Urchieguía

Inference of network-like evolutionary relationships between species from genomic data must address the interwoven signals from both gene flow and incomplete lineage sorting. The heavy computational demands of standard approaches to this…

Populations and Evolution · Quantitative Biology 2021-08-05 Elizabeth S. Allman , Hector Baños , John A. Rhodes

In this article, we propose tree edit distance with variables, which is an extension of the tree edit distance to handle trees with variables and has a potential application to measuring the similarity between mathematical formulas,…

Data Structures and Algorithms · Computer Science 2021-05-12 Tatsuya Akutsu , Tomoya Mori , Naotoshi Nakamura , Satoshi Kozawa , Yuhei Ueno , Thomas N. Sato

We give a 2-approximation algorithm for the Maximum Agreement Forest problem on two rooted binary trees. This NP-hard problem has been studied extensively in the past two decades, since it can be used to compute the Subtree…

Data Structures and Algorithms · Computer Science 2016-04-29 Frans Schalekamp , Anke van Zuylen , Suzanne van der Ster

The problem of comparing probability distributions is at the heart of many tasks in statistics and machine learning. Established comparison methods treat the standard setting that the distributions are supported in the same space. Recently,…

Metric Geometry · Mathematics 2024-10-01 Roan Talbut , Daniele Tramontano , Yueqi Cao , Mathias Drton , Anthea Monod

The inability to resolve deep node relationships of highly divergent/rapidly evolving protein families is a major factor that stymies evolutionary studies. In this manuscript, we propose a Multiple Sequence Alignment (MSA) independent…

As researchers collect increasingly large molecular data sets to reconstruct the Tree of Life, the heterogeneity of signals in the genomes of diverse organisms poses challenges for traditional phylogenetic analysis. A class of phylogenetic…

Populations and Evolution · Quantitative Biology 2015-09-11 Liang Liu , Zhenxiang Xi , Shaoyuan Wu , Charles Davis , Scott V. Edwards

Detecting variation in the evolutionary process along chromosomes is increasingly important as whole-genome data becomes more widely available. For example, factors such as incomplete lineage sorting, horizontal gene transfer, and…

Populations and Evolution · Quantitative Biology 2017-01-03 Elizabeth S. Allman , Laura S. Kubatko , John A. Rhodes

We analyse a maximum-likelihood approach for combining phylogenetic trees into a larger `supertree'. This is based on a simple exponential model of phylogenetic error, which ensures that ML supertrees have a simple combinatorial description…

Populations and Evolution · Quantitative Biology 2007-08-17 Mike Steel , Allen Rodrigo

Phylogenetic trait evolution models allow for the estimation of evolutionary correlations between a set of traits observed in a sample of related organisms. By directly modeling the evolution of the traits along an estimable phylogenetic…

In many interesting cases the reconstruction of a correct phylogeny is blurred by high mutation rates and/or horizontal transfer events. As a consequence a divergence arises between the true evolutionary distances and the differences…

Populations and Evolution · Quantitative Biology 2010-02-08 F. Tria , E. Caglioti , V. Loreto , A. Pagnani

Inferential summaries of tree estimates are useful in the setting of evolutionary biology, where phylogenetic trees have been built from DNA data since the 1960's. In bioinformatics, psychometrics and data mining, hierarchical clustering…

Applications · Statistics 2010-06-08 John Chakerian , Susan Holmes

In this paper, we address the question of comparison between populations of trees. We study an statistical test based on the distance between empirical mean trees, as an analog of the two sample z statistic for comparing two means. Despite…

Statistics Theory · Mathematics 2007-08-14 Ana Georgina Flesia , Ricardo Fraiman

Motivated by alignment of correlated sparse random graphs, we introduce a hypothesis testing problem of deciding whether or not two random trees are correlated. We obtain sufficient conditions under which this testing is impossible or…

Data Structures and Algorithms · Computer Science 2024-09-06 Luca Ganassali , Laurent Massoulié , Marc Lelarge

Dissimilarity measures for (possibly weighted) phylogenetic trees based on the comparison of their vectors of path lengths between pairs of taxa, have been present in the systematics literature since the early seventies. But, as far as…

Populations and Evolution · Quantitative Biology 2008-07-06 Gabriel Cardona , Merce Llabres , Francesc Rossello , Gabriel Valiente

Phylogenetics is now fundamental in life sciences, providing insights into the earliest branches of life and the origins and spread of epidemics. However, finding suitable phylogenies from the vast space of possible trees remains…

Populations and Evolution · Quantitative Biology 2024-01-24 Matthew J Penn , Neil Scheidwasser , Joseph Penn , Christl A Donnelly , David A Duchêne , Samir Bhatt

Phylogenetic trees illustrate the evolutionary history of genes and species. In most cases, although genes evolve along with the species they belong to, a species tree and gene tree are not identical, because of evolutionary events at the…

Data Structures and Algorithms · Computer Science 2019-02-25 Damir Hasic , Eric Tannier

A metric phylogenetic tree relating a collection of taxa induces weighted rooted triples and weighted quartets for all subsets of three and four taxa, respectively. New intertaxon distances are defined that can be calculated from these…

Populations and Evolution · Quantitative Biology 2020-02-12 Samaneh Yourdkhani , John A. Rhodes