Related papers: Radiotherapy using a laser proton accelerator
Stereotactic body radiation therapy (SBRT) refers to focusing high-energy rays in three-dimensional space on the tumor lesion area, reducing the dose received by surrounding normal tissues, which can effectively improve the local control…
Ion acceleration driven by superintense laser pulses is attracting an impressive and steadily increasing effort. Motivations can be found in the potential for a number of foreseen applications and in the perspective to investigate novel…
Focusing petawatt-level laser beams to a variety of spot sizes for different applications is expensive in cost, labor and space. In this paper, we propose a plasma lens to flexibly resize the laser beam by utilizing the laser self-focusing…
Recent progress in laser-driven plasma acceleration now enables the acceleration of electrons to several gigaelectronvolts. Taking advantage of these novel accelerators, ultra-short, compact and spatially coherent X-ray sources called…
A laser-driven particle accelerator based on plasmonic nano-antennas is proposed and analyzed. The concept utilizes the enhancement and localization of the electric field by nano-antennas to maximize the acceleration gradient and to…
Irradiations at Ultra High Dose Rate (UHDR) regimes, exceeding 40 Gy/s in single fractions lasting less than 200 ms, have shown an equivalent antitumor effect compared to conventional radio-therapy with reduced harm to normal tissues. This…
The paper reports the results of two-dimensional particle-in-cell simulations of proton beam acceleration at the interactions of a 130 fs laser pulse of intensity from the range of 10^21-10^23 W/cm^2, predicted for the Extreme Light…
Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods:…
Direct laser acceleration of ions by short frequency-chirped laser pulses is investigated theoretically. We demonstrate that intense beams of ions with a kinetic energy broadening of about 1 % can be generated. The chirping of the laser…
In the effort of achieving high-energetic ion beams from the interaction of ultrashort laser pulses with a plasma, volumetric acceleration mechanisms beyond Target Normal Sheath Acceleration have gained attention. A relativisticly intense…
Purpose: The purpose of this work was to provide a flexible platform for FLASH research with protons by adapting a former clinical pencil beam scanning gantry to irradiations with ultrahigh dose rates. Methods: PSI Gantry 1 treated patients…
Theranostics, the combination of diagnosis and therapy, has long held promise as a means to achieving personalised precision cancer treatments. However, despite its potential, theranostics has yet to realise significant clinical…
A target composition scheme to optimize the combined proton acceleration regime is presented and verified by two-dimensional particle-in-cell (2D PIC) simulations by using an ultra-intense circularly-polarized (CP) laser pulse irradiating…
In proton therapy, depth scanning of the irradiated object is performed by changing the Output Energy (OE) of the accelerated beam. In pulsed linear accelerators, adjustment of the OE is usually by changing the amplitude and/or phase of the…
Contact and projection electron radiography of static targets was demonstrated using a laser plasma accelerator driven by a kilojoule, picosecond class laser as a source of relativistic electrons with an average energy of 20 MeV. Objects…
The question of whether or not neutron therapy works has been answered. It is a qualified yes, as is the case with all of radiation therapy. But, neutron therapy has not kept pace with the rest of radiation therapy in terms of beam delivery…
We propose a new way of quick and very efficient acceleration of protons and/or electrons in relativistic bulk flows. The new mechanism takes advantage of conversion of particles from the charged state (protons or electrons/positrons) into…
Particle acceleration using ultraintense, ultrashort laser pulses is one of the most attractive topics in relativistic laser-plasma research. We report proton/ion acceleration in the intensity range of 5x1019 W/cm2 to 3.3x1020 W/cm2 by…
We demonstrate laser-plasma acceleration of high charge electron beams to the ~10 MeV scale using ultrashort laser pulses with as little energy as 10 mJ. This result is made possible by an extremely dense and thin hydrogen gas jet. Total…
For the laser wakefield acceleration, suppression of beam energy spread while keeping sufficient charge is one of the key challenges. In order to achieve this, we propose bichromatic laser ionization injection with combined laser…