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Related papers: Radiotherapy using a laser proton accelerator

200 papers

We propose a hybrid laser-driven ion acceleration scheme using a combination target of a solid foil and a density-tailored background plasma. In the first stage, a sub-relativistic proton beam can be generated by the radiation pressure…

Plasma Physics · Physics 2018-06-29 M. Liu , S. M. Weng , H. C. Wang , M. Chen , Q. Zhao , Z. M. Sheng , M. Q. He , Y. T. Li , J. Zhang

Proton therapy exploits the finite range of charged particles in tissue to achieve dose distributions no photon based modality can replicate. Yet the modality reaches fewer than 1 percent of patients who might benefit a gap rooted in cost…

Medical Physics · Physics 2026-04-28 Vivek Maradia , Martin Bues

Treatment delivery is largely determined by capabilities of the beam delivery system (BDS), where faster delivery can have many potential benefits including improved dosimetric quality, utility, cost effectiveness, patient throughput and…

Medical Physics · Physics 2026-01-21 Jacinta Yap , Adam Steinberg , Hannah Norman , Konrad Nesteruk , Suzie Sheehy

Computer tomography is one of the most promising new methods to image abnormal tissues inside the human body. Tomography is also used to position the patient accurately before radiation therapy. Hadron therapy for treating cancer has become…

The two dominant radiotherapy methods are either simplified in terms of beam generation and handling, which compromises the energy deposition curve in tissues (photon therapy), or require extensive accelerator facilities and complex beam…

Accelerator Physics · Physics 2023-09-12 Marta Monikowska , Marcin Patecki

Accelerator-based light sources such as storage rings and free-electron lasers use relativistic electron beams to produce intense radiation over a wide spectral range for fundamental research in physics, chemistry, materials science,…

Accelerator Physics · Physics 2015-06-19 Erik Hemsing , Gennady Stupakov , Dao Xiang , Alexander Zholents

Proton acceleration by using a 620-TW, 18-J laser pulse of peak intensity of $5\times 10^{21}$ W/cm$^{2}$ irradiating a disk target is examined using three-dimensional particle-in-cell simulations. It is shown that protons are accelerated…

Plasma Physics · Physics 2015-06-15 Toshimasa Morita

The proton irradiation accelerator is widely founded for industry application, and should be designed as compact, reliable, and easy operate. A 10 MeV proton beam is designed to be injected into the slow circulation ring with the repetition…

Accelerator Physics · Physics 2014-11-24 Yu-Wen An , Hong-Fei Ji , Sheng Wang , Shou-Yan Xu

In the last ten years the use of proton beams in radiation therapy has become a clinical tool for treatment of deep-seated tumours. LIBO is a RF compact and low cost proton linear accelerator (SCL type) for hadrontherapy. It is conceived by…

Accelerator Physics · Physics 2009-09-29 Paolo Berra

Laser-plasma acceleration is an emerging technique for accelerating electrons to high energies over very short distances. The accelerated electron bunches have femtosecond duration, making them particularly relevant for applications such as…

Purpose: This study explores the feasibility of dose-escalated proton beam therapy (dPBT) for Locally Advanced Pancreatic Cancer (LAPC) patients by modeling common patient scenarios using current clinically-adopted practices. Methods: Five…

Medical Physics · Physics 2025-07-30 M. A. McIntyre , J. Midson , P. Wilson , P Gorayski , C. E. Hsieh , S. W. Wu , E. Bezak

Compared with conventional accelerators, laser plasma accelerators can generate high energy ions at a greatly reduced scale, due to their TV/m acceleration gradient. A compact laser plasma accelerator (CLAPA) has been built at the Institute…

Accelerator Physics · Physics 2017-10-17 J. G. Zhu , K. Zhu , L. Tao , X. H. Xu , C. Lin , W. J. Ma , H. Y. Lu , Y. Y. Zhao , Y. R. Lu , J. E. Chen , X. Q. Yan

Relativistic positron beams are required for fundamental research in nonlinear strong field QED, plasma physics, and laboratory astrophysics. Positrons are difficult to create and manipulate due to their short lifetime, and their energy…

Plasma Physics · Physics 2023-02-08 B. Martinez , B. Barbosa , M. Vranic

We access the possibility of using the conventional RF accelerator as an injector for the plasma driven wakefield accelerator. Conventional accelerators deliver high quality beams with low emittance and low energy spread. Once injected into…

Particle physics simulations are the cornerstone of nuclear engineering applications. Among them radiotherapy (RT) is crucial for society, with 50% of cancer patients receiving radiation treatments. For the most precise targeting of tumors,…

Machine Learning · Computer Science 2021-09-10 Oscar Pastor-Serrano , Zoltán Perkó

The challenge of removing cancerous cells lies in the limitation of organ at risk, which restricts the ability to increase the radiation dose adequately for enhancing treatment effectiveness. This survey provides a comprehensive overview of…

Medical Physics · Physics 2023-07-27 Amir Moslemi , Navid Khaledi

A scheme for fast, compact, and controllable acceleration of heavy particles in vacuum is proposed, in which two counterpropagating lasers with variable frequencies drive a beat-wave structure with variable phase velocity, thus allowing for…

Plasma Physics · Physics 2008-11-26 F. Peano , J. Vieira , L. O. Silva , R. Mulas , G. Coppa

An all-optical centimeter-scale laser-plasma positron accelerator is modeled to produce quasi-monoenergetic beams with tunable ultra-relativistic energies. A new principle elucidated here describes the trapping of divergent positrons that…

Plasma Physics · Physics 2018-08-15 Aakash A. Sahai

High intensity laser driven proton beams are at present receiving much attention. The reasons for this are many but high on the list is the potential to produce compact accelerators. However two of the limitations of this technology is that…

Fundamental questions on the nature of matter and energy have found answers thanks to the use of particle accelerators. Societal applications, such as cancer treatment or cancer imaging, illustrate the impact of accelerators in our current…

Accelerator Physics · Physics 2017-05-31 V. Malka