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Advances in large-scale neural recordings have expanded our ability to describe the activity of distributed brain circuits. However, understanding how neural population dynamics differ across regions and behavioral contexts remains…

Biological and artificial learners are inherently exposed to a stream of data and experience throughout their lifetimes and must constantly adapt to, learn from, or selectively ignore the ongoing input. Recent findings reveal that, even…

Neurons and Cognition · Quantitative Biology 2026-04-13 Farhad Pashakhanloo

Modern learning systems increasingly interact with data that evolve over time and depend on hidden internal state. We ask a basic question: when is such a dynamical system learnable from observations alone? This paper proposes a research…

Machine Learning · Computer Science 2025-12-23 Elad Hazan , Shai Shalev Shwartz , Nathan Srebro

We propose a new model in order to study behaviors of self-organized system such as a group of animals. We assume that the individuals have two degrees of freedom corresponding one to their internal state and the other to their external…

Biological Physics · Physics 2015-10-23 P. The Nguyen , V. Thanh Ngo , H. T. Diep

Electrical brain stimulation relies on externally applied currents to modulate neural activity, but safety constraints require each stimulation cycle to be charge-balanced, enforcing a zero net injected charge. However, how such…

Systems and Control · Electrical Eng. & Systems 2025-12-09 Yuzhen Qin , Zonglin Liu , Marcel van Gerven

Living organisms must actively maintain themselves in order to continue existing. Autopoiesis is a key concept in the study of living organisms, where the boundaries of the organism is not static by dynamically regulated by the system…

Neural and Evolutionary Computing · Computer Science 2020-01-29 Atsushi Masumori , Lana Sinapayen , Norihiro Maruyama , Takeshi Mita , Douglas Bakkum , Urs Frey , Hirokazu Takahashi , Takashi Ikegami

Cortical neurons emit seemingly erratic trains of action potentials or "spikes," and neural network dynamics emerge from the coordinated spiking activity within neural circuits. These rich dynamics manifest themselves in a variety of…

Neurons and Cognition · Quantitative Biology 2022-04-01 Braden A. W. Brinkman , Han Yan , Arianna Maffei , Il Memming Park , Alfredo Fontanini , Jin Wang , Giancarlo La Camera

We study the dynamics of excitable integrate-and-fire neurons in a small-world network. At low densities $p$ of directed random connections, a localized transient stimulus results in either self-sustained persistent activity or in a brief…

Pattern Formation and Solitons · Physics 2009-11-10 Alex Roxin , Hermann Riecke , Sara A. Solla

Neurons can display highly variable dynamics. While such variability presumably supports the wide range of behaviors generated by the organism, their gene expressions are relatively stable in the adult brain. This suggests that neuronal…

Neurons and Cognition · Quantitative Biology 2023-11-07 Lu Mi , Trung Le , Tianxing He , Eli Shlizerman , Uygar Sümbül

Attractor dynamics are a fundamental computational motif in neural circuits, supporting diverse cognitive functions through stable, self-sustaining patterns of neural activity. In these lecture notes, we review four key examples that…

Neurons and Cognition · Quantitative Biology 2026-01-30 Tala Fakhoury , Elia Turner , Sushrut Thorat , Athena Akrami

Understanding how neural dynamics shape cognitive experiences remains a central challenge in neuroscience and psychiatry. Here, we present a novel framework leveraging state-to-output controllability from dynamical systems theory to model…

We demonstrate, both analytically and numerically, that learning dynamics of neural networks is generically attracted towards a self-organized critical state. The effect can be modeled with quartic interactions between non-trainable…

Statistical Mechanics · Physics 2021-07-09 Mikhail I. Katsnelson , Vitaly Vanchurin , Tom Westerhout

Trial-to-trial variability is an essential feature of neural responses, but its source is a subject of active debate. Response variability (Mast and Victor, 1991; Arieli et al., 1995 & 1996; Anderson et al., 2000 & 2001; Kenet et al., 2003;…

Neurons and Cognition · Quantitative Biology 2010-08-04 L F Abbott , Kanaka Rajan , Haim Sompolinsky

We present a numerical method for learning unknown nonautonomous stochastic dynamical system, i.e., stochastic system subject to time dependent excitation or control signals. Our basic assumption is that the governing equations for the…

Machine Learning · Computer Science 2025-03-04 Yuan Chen , Dongbin Xiu

The study of balanced networks of excitatory and inhibitory neurons has led to several open questions. On the one hand it is yet unclear whether the asynchronous state observed in the brain is autonomously generated, or if it results from…

Neurons and Cognition · Quantitative Biology 2016-09-22 Rodrigo Echeveste , Claudius Gros

Adaptive behavior, cognition and emotion are the result of a bewildering variety of brain spatiotemporal activity patterns. An important problem in neuroscience is to understand the mechanism by which the human brain's 100 billion neurons…

Neurons and Cognition · Quantitative Biology 2011-05-09 Paul Expert , Renaud Lambiotte , Dante R. Chialvo , Kim Christensen , Henrik Jeldtoft Jensen , David J. Sharp , Federico Turkheimer

Human learning is a complex phenomenon requiring flexibility to adapt existing brain function and precision in selecting new neurophysiological activities to drive desired behavior. These two attributes -- flexibility and selection -- must…

Neurons and Cognition · Quantitative Biology 2013-06-28 Danielle S. Bassett , Nicholas F. Wymbs , Mason A. Porter , Peter J. Mucha , Jean M. Carlson , Scott T. Grafton

We investigate the performance of sparsely-connected networks of integrate-and-fire neurons for ultra-short term information processing. We exploit the fact that the population activity of networks with balanced excitation and inhibition…

Neurons and Cognition · Quantitative Biology 2007-05-23 Julien Mayor , Wulfram Gerstner

The complexity of neural dynamics stems in part from the complexity of the underlying anatomy. Yet how the organization of white matter architecture constrains how the brain transitions from one cognitive state to another remains unknown.…

Neurons and Cognition · Quantitative Biology 2017-01-11 Shi Gu , Richard F. Betzel , Matthew Cieslak , Philip R. Delio , Scott T. Grafton , Fabio Pasqualetti , Danielle S. Bassett

Autonomous artificial agents must be able to learn behaviors in complex environments without humans to design tasks and rewards. Designing these functions for each environment is not feasible, thus, motivating the development of intrinsic…

Machine Learning · Computer Science 2025-02-20 Alana Santana , Paula P. Costa , Esther L. Colombini