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In this thesis, we have studied the large scale structure and system level dynamics of certain biological networks using tools from graph theory, computational biology and dynamical systems. We study the structure and dynamics of large…

Molecular Networks · Quantitative Biology 2008-12-31 Areejit Samal

A complexity-theoretic approach to studying biological networks is proposed. A simple graph representation is used where molecules (DNA, RNA, proteins and chemicals) are vertices and relations between them are directed and signed…

Social and Information Networks · Computer Science 2018-04-25 Ali Atiia , François Major , Jérôme Waldispühl

What is a complex network? How do we characterize complex networks? Which systems can be studied from a network approach? In this text, we motivate the use of complex networks to study and understand a broad panoply of systems, ranging from…

Physics and Society · Physics 2007-11-27 Pedro G. Lind

Complex networks evolve and vary their structure as time goes by. In particular, the links in those networks have both a sign and a directionality. To understand their structural principles, we measure the network motifs, which are patterns…

Physics and Society · Physics 2023-06-28 Youngjai Park , Mi Jin Lee , Seung-Woo Son

For decades, complex networks, such as social networks, biological networks, chemical networks, technological networks, have been used to study the evolution and dynamics of different kinds of complex systems. These complex systems can be…

Social and Information Networks · Computer Science 2020-12-16 Akrati Saxena

In communication networks structure and dynamics are tightly coupled. The structure controls the flow of information and is itself shaped by the dynamical process of information exchanged between nodes. In order to reconcile structure and…

Physics and Society · Physics 2013-04-08 Jan O. Haerter , Bjorn Jamtveit , Joachim Mathiesen

We consider networks of dynamical units that evolve in time according to different laws, and are coupled to each other in highly irregular ways. Studying how to steer the dynamics of such systems towards a desired evolution is of great…

Physics and Society · Physics 2020-12-01 Ricardo Gutiérrez , Massimo Materassi , Stefano Focardi , Stefano Boccaletti

This paper (parts I and II) provides an expository introduction to monotone and near-monotone dynamical systems associated to biochemical networks, those whose graphs are consistent or near-consistent. Many conclusions can be drawn from…

Molecular Networks · Quantitative Biology 2007-05-23 Eduardo D. Sontag

The understanding of emergent collective phenomena in natural and social systems has driven the interest of scientists from different disciplines during decades. Among these phenomena, the synchronization of a set of interacting individuals…

Statistical Mechanics · Physics 2007-05-23 Jesus Gomez-Gardenes , Yamir Moreno , Alex Arenas

We present and analyze a topologically induced transition from ordered, synchronized to disordered dynamics in directed networks of oscillators. The analysis reveals where in the space of networks this transition occurs and its underlying…

Disordered Systems and Neural Networks · Physics 2007-05-23 Marc Timme

The behavior of complex systems is determined not only by the topological organization of their interconnections but also by the dynamical processes taking place among their constituents. A faithful modeling of the dynamics is essential…

Physics and Society · Physics 2015-05-20 R. Lambiotte , R. Sinatra , J. -C. Delvenne , T. S. Evans , M. Barahona , V. Latora

As individuals communicate, their exchanges form a dynamic network. We demonstrate, using time series analysis of communication in three online settings, that network structure alone can be highly revealing of the diversity and novelty of…

Social and Information Networks · Computer Science 2012-05-23 Chun-Yuen Teng , Liuling Gong , Avishay Livne , Celso Brunetti , Lada A. Adamic

From social interactions to the human brain, higher-order networks are key to describe the underlying network geometry and topology of many complex systems. While it is well known that network structure strongly affects its function, the…

Statistical Mechanics · Physics 2022-01-11 Ana P Millán , Reza Ghorbanchian , Nicolò Defenu , Federico Battiston , Ginestra Bianconi

Networks are useful descriptions of the structure of many complex systems. Unsurprisingly, it is thus important to analyze the robustness of networks in many scientific disciplines. In applications in communication, logistics, finance,…

Physics and Society · Physics 2024-09-16 Alice C. Schwarze , Jessica Jiang , Jonny Wray , Mason A. Porter

Scale-free and non-computable characteristics of natural networks are found to result from the least-time dispersal of energy. To consider a network as a thermodynamic system is motivated since ultimately everything that exists can be…

General Physics · Physics 2011-06-22 Tuomo Hartonen , Arto Annila

How do networks of relationships evolve over time? We analyse a dataset tracking the social interactions of 900 individuals over four years. Despite continuous shifts in individual relationships, the macroscopic structural properties of the…

Physics and Society · Physics 2025-06-04 Miguel A. González-Casado , Andreia Sofia Teixeira , Angel Sánchez

An important part of the analysis of bio-molecular networks is to detect different functional units. Different functions are reflected in a different evolutionary dynamics, and hence in different statistical characteristics of network…

Molecular Networks · Quantitative Biology 2007-05-23 Johannes Berg , Michael Lässig

Many systems on our planet are known to shift abruptly and irreversibly from one state to another when they are forced across a "tipping point," such as mass extinctions in ecological networks, cascading failures in infrastructure systems,…

Quantitative Methods · Quantitative Biology 2022-05-23 Xueming Liu , Daqing Li , Manqing Ma , Boleslaw K. Szymanski , H Eugene Stanley , Jianxi Gao

Network science has become an essential interdisciplinary tool for understanding complex biological systems. However, because these systems undergo continuous, often stimulus-driven changes in both structure and function, traditional static…

Molecular Networks · Quantitative Biology 2025-05-19 Abir Khazaal , Fatemeh Vafaee

Network theory is rapidly changing our understanding of complex systems, but the relevance of topological features for the dynamic behavior of metabolic networks, food webs, production systems, information networks, or cascade failures of…

Disordered Systems and Neural Networks · Physics 2007-05-23 Dirk Helbing , Ulrich Witt , Stefan Laemmer , Thomas Brenner