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Immune cells learn about their antigenic targets using tactile sense: during recognition, a highly organized yet dynamic motif, named immunological synapse, forms between immune cells and antigen-presenting cells (APCs). Via synapses,…

Biological Physics · Physics 2018-12-12 Miloš Knežević , Shenshen Wang

Agent-based modeling (ABM) is a well-established paradigm for simulating complex systems via interactions between constituent entities. Machine learning (ML) refers to approaches whereby statistical algorithms 'learn' from data on their…

Quantitative Methods · Quantitative Biology 2022-11-10 Nikita Sivakumar , Cameron Mura , Shayn M. Peirce

The Dendritic Cell Algorithm (DCA) is inspired by the function of the dendritic cells of the human immune system. In nature, dendritic cells are the intrusion detection agents of the human body, policing the tissue and organs for potential…

Artificial Intelligence · Computer Science 2010-07-05 Julie Greensmith , Uwe Aickelin , Steve Cayzer

Biological systems are generally complicated and/or complex. In the former approach, one sets up a model with a large number of parameters to describe the system in detail. The latter approach focuses on understanding the universal aspects…

Biological Physics · Physics 2026-03-19 Kunihiko Kaneko

Receptor-induced apoptosis is a complex signal transduction pathway involving numerous protein/protein interactions and post-transcriptional modifications. The response to death receptor stimulation varies significantly from one cell line…

Quantitative Methods · Quantitative Biology 2017-12-20 François Bertaux , Dirk Drasdo , Gregory Batt

In this thesis, the uses of Artificial Immune Systems (AIS) in Machine learning is studded. the thesis focus on some of immune inspired algorithms such as clonal selection algorithm and artificial immune network. The effect of changing the…

Neural and Evolutionary Computing · Computer Science 2017-09-14 Mohammad Tarek Al Muallim

Nature has always been an inspiration to researchers with its diversity and robustness of its systems, and Artificial Immune Systems are one of them. Many algorithms were inspired by ongoing discoveries of biological immune systems…

Networking and Internet Architecture · Computer Science 2014-03-13 Amira Sayed A. Aziz , Ahmad Taher Azar , Aboul Ella Hassanien , Sanaa El-Ola Hanafy

Antibodies, a prominent class of approved biologics, play a crucial role in detecting foreign antigens. The effectiveness of antigen neutralisation and elimination hinges upon the strength, sensitivity, and specificity of the…

Quantitative Methods · Quantitative Biology 2023-09-06 Bruna Moreira da Silva , David B. Ascher , Nicholas Geard , Douglas E. V. Pires

Metabolic networks perform some of the most fundamental functions in living cells, including energy transduction and building block biosynthesis. While these are the best characterized networks in living systems, understanding their…

Molecular Networks · Quantitative Biology 2010-04-05 W. J. Riehl , P. L. Krapivsky , S. Redner , D. Segre

It has been known for some time that human autoimmune diseases can be triggered by viral infections. Several possible mechanisms of interactions between a virus and immune system have been analysed, with a prevailing opinion being that the…

Populations and Evolution · Quantitative Biology 2012-09-21 K. B. Blyuss , L. B. Nicholson

Advances in healthcare and in the quality of life significantly increase human life expectancy. With the ageing of populations, new un-faced challenges are brought to science. The human body is naturally selected to be well-functioning…

Artificial Intelligence · Computer Science 2016-07-21 Grazziela P. Figueredo , Peer-Olaf Siebers , Uwe Aickelin , Amanda Whitbrook , Jonathan M. Garibaldi

AI technology has a long history which is actively and constantly changing and growing. It focuses on intelligent agents, which contain devices that perceive the environment and based on which takes actions in order to maximize goal success…

Artificial Intelligence · Computer Science 2018-04-05 Jahanzaib Shabbir , Tarique Anwer

The last few years have witnessed substantial progress in the field of embodied AI where artificial agents, mirroring biological counterparts, are now able to learn from interaction to accomplish complex tasks. Despite this success,…

Computer Vision and Pattern Recognition · Computer Science 2022-01-04 Sarah Pratt , Luca Weihs , Ali Farhadi

We introduce bio-inspired artificial neural networks consisting of neurons that are additionally characterized by spatial positions. To simulate properties of biological systems we add the costs penalizing long connections and the proximity…

Neural and Evolutionary Computing · Computer Science 2019-10-08 Maciej Wołczyk , Jacek Tabor , Marek Śmieja , Szymon Maszke

Biological systems perform an astonishing array of dynamical processes -- including development and repair, regulation, behavior and motor control, sensing and signaling, and adaptation, among others. Powered by the transduction of stored…

Soft Condensed Matter · Physics 2025-09-04 James Clarke , Jake McGrath , Colin Johnson , José Alvarado

Reaction systems are a computational model inspired by the bio-chemical reactions that happen inside biological cells. They have been and currently are studied for their many nice theoretical properties. They are also a useful modeling tool…

Formal Languages and Automata Theory · Computer Science 2020-08-05 Claudio Ferretti , Alberto Leporati , Luca Manzoni , Antonio E. Porreca

Within the germinal center in follicles, B-cells proliferate, mutate and differentiate, while being submitted to a powerful selection~: a micro-evolutionary mechanism at the heart of adaptive immunity. A new foreign pathogen is confronted…

Probability · Mathematics 2016-02-12 Irene Balelli , Vuk Milisic , Gilles Wainrib

An improved email classification method based on Artificial Immune System is proposed in this paper to develop an immune based system by using the immune learning, immune memory in solving complex problems in spam detection. An optimized…

Cryptography and Security · Computer Science 2014-02-07 Ismaila Idris , Shafii Muhammad Abdulhamid

In this book chapter we describe recent applications of artificial intelligence and in particular machine learning to active matter systems. Active matter is composed of agents, or particles, that are capable of propelling themselves. While…

Soft Condensed Matter · Physics 2025-01-16 Hartmut Löwen , Benno Liebchen

Immune cells coordinate their efforts for the correct and efficient functioning of the immune system (IS). Each cell type plays a distinct role and communicates with other cell types through mediators such as cytokines, chemokines and…

Molecular Networks · Quantitative Biology 2007-05-23 Paolo Tieri , Silvana Valensin , Vito Latora , Gastone C. Castellani , Massimo Marchiori , Daniel Remondini , Claudio Franceschi