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In spite of their many facets, the phenomena of autoimmunity and immunodeficiency seem to be related to each other through the subtle links connecting retroviral mutation and action to immune response and adaptation. In a previous work, we…

Populations and Evolution · Quantitative Biology 2016-07-01 Valmir C. Barbosa , Raul Donangelo , Sergio R. Souza

The biological immune system is a robust, complex, adaptive system that defends the body from foreign pathogens. It is able to categorize all cells (or molecules) within the body as self-cells or non-self cells. It does this with the help…

Artificial Intelligence · Computer Science 2010-07-05 Uwe Aickelin , Dipankar Dasgupta

Inverse reinforcement learning (IRL) is the problem of inferring the reward function of an agent, given its policy or observed behavior. Analogous to RL, IRL is perceived both as a problem and as a class of methods. By categorically…

Machine Learning · Computer Science 2020-11-19 Saurabh Arora , Prashant Doshi

Social interactions increasingly involve artificial agents, such as conversational or collaborative bots. Understanding trust and prosociality in these settings is fundamental to improve human-AI teamwork. Research in biology and social…

Human-Computer Interaction · Computer Science 2025-12-25 Isabel Neto , Alexandre S. Pires , Filipa Correia , Fernando P. Santos

Force interaction is inevitable when robots face multiple operation scenarios. How to make the robot competent in force control for generalized operations such as multi-tasks still remains a challenging problem. Aiming at the…

Robotics · Computer Science 2024-03-26 Bo Zhou , Yuyao Sun , Wenbo Liu , Ruixuan Jiao , Fang Fang , Shihua Li

This letter proposes an Adversarial Inverse Reinforcement Learning (AIRL)-based energy management method for a smart home, which incorporates an implicit thermal dynamics model. In the proposed method, historical optimal decisions are first…

Systems and Control · Electrical Eng. & Systems 2025-06-03 Jiadong He , Liang Yu , Zhiqiang Chen , Dawei Qiu , Dong Yue , Goran Strbac , Meng Zhang , Yujian Ye , Yi Wang

Network Intrusion Detection Systems (NIDS) are computer systems which monitor a network with the aim of discerning malicious from benign activity on that network. While a wide range of approaches have met varying levels of success, most…

Artificial Intelligence · Computer Science 2010-07-05 Gianni Tedesco , Uwe Aickelin

As AI systems become increasingly autonomous, reliably aligning their decision-making with human preferences is essential. Inverse reinforcement learning (IRL) offers a promising approach to infer preferences from demonstrations. These…

Machine Learning · Computer Science 2025-09-22 Ondrej Bajgar , Dewi S. W. Gould , Jonathon Liu , Alessandro Abate , Konstantinos Gatsis , Michael A. Osborne

Most biological rates and times decrease systematically with organism body size. We use an ordinary differential equation (ODE) model of West Nile Virus in birds to show that pathogen replication rates decline with host body size, but…

Quantitative Methods · Quantitative Biology 2010-08-10 Soumya Banerjee , Melanie Moses

We argue that immune system is an adaptive complex system. It is shown that it has emergent properties. Its network structure is of the small world network type. The network is of the threshold type, which helps in avoiding autoimmunity. It…

Populations and Evolution · Quantitative Biology 2008-01-08 E. Ahmed , A. H. Hashish

Swarm robotic systems are mainly inspired by swarms of socials insects and the collective emergent behavior that arises from their cooperation at the lower lever. Despite the limited sensory ability, computational power, and communication…

Systems and Control · Computer Science 2013-03-01 Wesam Elshamy

This paper demonstrates that a set of behaviours evolved in simulation on a miniature robot (epuck) can be transferred to a much larger scale platform (a virtual Pioneer P3-DX) that also differs in shape, sensor type, sensor configuration…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Amanda Whitbrook , Uwe Aickelin , Jonathan M. Garibaldi

We are interested in modeling theoretical immunology within a statistical mechanics flavor: focusing on the antigen-independent maturation process of B-cells, in this paper we try to revise the problem of self vs non-self discrimination by…

Cell Behavior · Quantitative Biology 2010-12-10 Adriano Barra , Silvio Franz , Thiago Sabetta

Artificial Immune Systems have been successfully applied to a number of problem domains including fault tolerance and data mining, but have been shown to scale poorly when applied to computer intrusion detec- tion despite the fact that the…

Artificial Intelligence · Computer Science 2010-07-05 Jamie Twycross , Uwe Aickelin , Amanda Whitbrook

Adversarial attacks against deep neural networks (DNNs) are continuously evolving, requiring increasingly powerful defense strategies. We develop a novel adversarial defense framework inspired by the adaptive immune system: the Robust…

Neural and Evolutionary Computing · Computer Science 2022-02-23 Ren Wang , Tianqi Chen , Stephen Lindsly , Cooper Stansbury , Alnawaz Rehemtulla , Indika Rajapakse , Alfred Hero

Making decisions in complex driving environments is a challenging task for autonomous agents. Imitation learning methods have great potentials for achieving such a goal. Adversarial Inverse Reinforcement Learning (AIRL) is one of the…

Artificial Intelligence · Computer Science 2021-03-29 Pin Wang , Dapeng Liu , Jiayu Chen , Hanhan Li , Ching-Yao Chan

We analyse a minimal model for the primary response in the adaptive immune system comprising three different players: antigens, T and B cells. We assume B-T interactions to be diluted and sampled locally from heterogeneous degree…

Cell Behavior · Quantitative Biology 2015-09-30 Silvia Bartolucci , Alessia Annibale

Artificial immune system can be used to generate schedules in changing environments and it has been proven to be more robust than schedules developed using a genetic algorithm. Good schedules can be produced especially when the number of…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin , Edmund Burke , Aniza Din

This paper introduces Adversarial Resilience Learning (ARL), a concept to model, train, and analyze artificial neural networks as representations of competitive agents in highly complex systems. In our examples, the agents normally take the…

Artificial Intelligence · Computer Science 2018-11-16 Lars Fischer , Jan-Menno Memmen , Eric MSP Veith , Martin Tröschel

The symmetrical network theory is a framework for understanding the immune system, that dates back to the mid 1970s. The symmetrical network theory is based on symmetrical stimulatory, inhibitory and killing interactions between clones that…

Populations and Evolution · Quantitative Biology 2008-12-31 Geoffrey W. Hoffmann