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Phylogenetic networks are rooted directed acyclic graphs that represent evolutionary relationships between species whose past includes reticulation events such as hybridisation and horizontal gene transfer. To search the space of…

Combinatorics · Mathematics 2019-04-09 Jonathan Klawitter , Simone Linz

Comparing and computing distances between phylogenetic trees are important biological problems, especially for models where edge lengths play an important role. The geodesic distance measure between two phylogenetic trees with edge lengths…

Populations and Evolution · Quantitative Biology 2009-11-05 Megan Owen , J. Scott Provan

Phylogenetic trees and networks are leaf-labelled graphs used to model evolution. Display graphs are created by identifying common leaf labels in two or more phylogenetic trees or networks. The treewidth of such graphs is bounded as a…

Data Structures and Algorithms · Computer Science 2018-09-05 Remie Janssen , Mark Jones , Steven Kelk , Georgios Stamoulis , Taoyang Wu

Phylogenetic tree comparison metrics are an important tool in the study of evolution, and hence the definition of such metrics is an interesting problem in phylogenetics. In a paper in Taxon fifty years ago, Sokal and Rohlf proposed to…

Populations and Evolution · Quantitative Biology 2013-01-22 Gabriel Cardona , Arnau Mir , Francesc Rossello , Lucia Rotger , David Sanchez

Maximum parsimony distance is a measure used to quantify the dissimilarity of two unrooted phylogenetic trees. It is NP-hard to compute, and very few positive algorithmic results are known due to its complex combinatorial structure. Here we…

Data Structures and Algorithms · Computer Science 2020-04-07 Mark Jones , Steven Kelk , Leen Stougie

Phylogenetic networks are a generalization of phylogenetic trees that allow for representation of reticulate evolution. Recently, a space of unrooted phylogenetic networks was introduced, where such a network is a connected graph in which…

Populations and Evolution · Quantitative Biology 2017-03-09 Andrew Francis , Katharina Huber , Vincent Moulton , Taoyang Wu

Phylogenetic networks are a generalization of phylogenetic trees that allow for the representation of non-treelike evolutionary events, like recombination, hybridization, or lateral gene transfer. In a recent series of papers devoted to the…

Populations and Evolution · Quantitative Biology 2007-07-17 Gabriel Cardona , Francesc Rossello , Gabriel Valiente

Rooted phylogenetic networks provide an explicit representation of the evolutionary history of a set $X$ of sampled species. In contrast to phylogenetic trees which show only speciation events, networks can also accommodate reticulate…

Combinatorics · Mathematics 2021-01-01 Peter L. Erdos , Charles Semple , Mike Steel

Distance-based phylogenetic algorithms attempt to solve the NP-hard least squares phylogeny problem by mapping an arbitrary dissimilarity map representing biological data to a tree metric. The set of all dissimilarity maps is a Euclidean…

Populations and Evolution · Quantitative Biology 2013-07-24 Ruth Davidson , Seth Sullivant

We compare the phylogenetic tensors for various trees and networks for two, three and four taxa. If the probability spaces between one tree or network and another are not identical then there will be phylogenetic tensors that could have…

Populations and Evolution · Quantitative Biology 2016-06-24 Jonathan Mitchell

Phylogenetic networks are a type of leaf-labelled, acyclic, directed graph used by biologists to represent the evolutionary history of species whose past includes reticulation events. A phylogenetic network is tree-child if each non-leaf…

Combinatorics · Mathematics 2017-11-27 Magnus Bordewich , Katharina T Huber , Vincent Moulton , Charles Semple

Phylogenetic trees are simple models of evolutionary processes. They describe conditionally independent divergent evolution of taxa from common ancestors. Phylogenetic trees commonly do not have enough flexibility to adequately model all…

Populations and Evolution · Quantitative Biology 2025-11-11 Jonathan D. Mitchell , Barbara R. Holland

Phylogenetic trees canonically arise as embeddings of phylogenetic networks. We recently showed that the problem of deciding if two phylogenetic networks embed the same sets of phylogenetic trees is computationally hard, \blue{in…

Combinatorics · Mathematics 2021-04-13 Janosch Doecker , Simone Linz , Charles Semple

The goal of this paper is to study the similarity between sequences using a distance between the \emph{context} trees associated to the sequences. These trees are defined in the framework of \emph{Sparse Probabilistic Suffix Trees} (SPST),…

Applications · Statistics 2008-04-29 Florencia Leonardi , Sergio R. Matioli , Hugo A. Armelin , Antonio Galves

Phylogenetics is a branch of computational biology that studies the evolutionary relationships among biological entities. Its long history and numerous applications notwithstanding, inference of phylogenetic trees from sequence data remains…

Populations and Evolution · Quantitative Biology 2024-03-26 Mingyang Zhou , Zichao Yan , Elliot Layne , Nikolay Malkin , Dinghuai Zhang , Moksh Jain , Mathieu Blanchette , Yoshua Bengio

Phylogenetic networks generalize phylogenetic trees by allowing reticulate evolutionary events such as horizontal gene transfer and hybridization. Among the many subclasses of phylogenetic networks, orchard networks have attracted…

Populations and Evolution · Quantitative Biology 2026-05-20 Peng Li , Zhiwei Liu , Yangjing Long

Phylogenetic tree reconstruction is traditionally based on multiple sequence alignments (MSAs) and heavily depends on the validity of this information bottleneck. With increasing sequence divergence, the quality of MSAs decays quickly.…

Populations and Evolution · Quantitative Biology 2011-01-11 Roland F. Schwarz , William Fletcher , Frank Förster , Benjamin Merget , Matthias Wolf , Jörg Schultz , Florian Markowetz

In phylogenetic networks, it is desirable to estimate edge lengths in substitutions per site or calendar time. Yet, there is a lack of scalable methods that provide such estimates. Here we consider the problem of obtaining edge length…

Populations and Evolution · Quantitative Biology 2024-08-06 Jingcheng Xu , Cécile Ané

Tree comparison metrics have proven to be an invaluable aide in the reconstruction and analysis of phylogenetic (evolutionary) trees. The path-length distance between trees is a particularly attractive measure as it reflects differences in…

Data Structures and Algorithms · Computer Science 2018-11-05 David Bryant , Celine Scornavacca

When estimating a phylogeny from a multiple sequence alignment, researchers often assume the absence of recombination. However, if recombination is present, then tree estimation and all downstream analyses will be impacted, because…