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As a hybrid imaging technology, photoacoustic microscopy (PAM) imaging suffers from noise due to the maximum permissible exposure of laser intensity, attenuation of ultrasound in the tissue, and the inherent noise of the transducer.…
Inspired by the robustness and efficiency of sparse representation in sparse coding based image restoration models, we investigate the sparsity of neurons in deep networks. Our method structurally enforces sparsity constraints upon hidden…
Blind deconvolution is a challenging problem, but in low-light it is even more difficult. Existing algorithms, both classical and deep-learning based, are not designed for this condition. When the photon shot noise is strong, conventional…
Deep neural networks have been widely used in image denoising during the past few years. Even though they achieve great success on this problem, they are computationally inefficient which makes them inappropriate to be implemented in mobile…
The problem of Poisson denoising appears in various imaging applications, such as low-light photography, medical imaging and microscopy. In cases of high SNR, several transformations exist so as to convert the Poisson noise into an additive…
Image denoising is an essential tool in computational photography. Standard denoising techniques, which use deep neural networks at their core, require pairs of clean and noisy images for its training. If we do not possess the clean…
We propose a new image denoising algorithm when the data is contaminated by a Poisson noise. As in the Non-Local Means filter, the proposed algorithm is based on a weighted linear combination of the bserved image. But in contract to the…
Denoising extreme low light images is a challenging task due to the high noise level. When the illumination is low, digital cameras increase the ISO (electronic gain) to amplify the brightness of captured data. However, this in turn…
This paper demonstrates a practical method that can correct spatial varying blur from a set of images of the same object. The algorithm jointly estimates the object and local point spread functions~(PSF). The method prioritizes sections…
We propose a new fast algorithm for solving one of the standard formulations of frame-based image deconvolution: an unconstrained optimization problem, involving an $\ell_2$ data-fidelity term and a non-smooth regularizer. Our approach is…
Image denoising is an important pre-processing step in medical image analysis. Different algorithms have been proposed in past three decades with varying denoising performances. More recently, having outperformed all conventional methods,…
Small compression noises, despite being transparent to human eyes, can adversely affect the results of many image restoration processes, if left unaccounted for. Especially, compression noises are highly detrimental to inverse operators of…
We present a physics-informed deep learning framework to address common limitations in Confocal Laser Scanning Microscopy (CLSM), such as diffraction limited resolution, noise, and undersampling due to low laser power conditions. The…
Non-blind image deblurring is typically formulated as a linear least-squares problem regularized by natural priors on the corresponding sharp picture's gradients, which can be solved, for example, using a half-quadratic splitting method…
Increasing the resolution of image sensors has been a never ending struggle since many years. In this paper, we propose a novel image sensor layout which allows for the acquisition of images at a higher resolution and improved quality. For…
Fluorescence lifetime imaging microscopy (FLIM) systems are limited by their slow processing speed, low signal-to-noise ratio (SNR), and expensive and challenging hardware setups. In this work, we demonstrate applying a denoising…
Photoacoustic imaging is a new imaging technology in recent years, which combines the advantages of high resolution and rich contrast of optical imaging with the advantages of high penetration depth of acoustic imaging. Photoacoustic…
The goal of blind image deblurring is to recover a sharp image from a motion blurred one without knowing the camera motion. Current state-of-the-art methods have a remarkably good performance on images with no noise or very low noise…
Inverse problems in image reconstruction are fundamentally complicated by unknown noise properties. Classical iterative deconvolution approaches amplify noise and require careful parameter selection for an optimal trade-off between…
The quality of microscopy images often suffers from optical aberrations. These aberrations and their associated point spread functions have to be quantitatively estimated to restore aberrated images. The recent state-of-the-art method…