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Network embedding approaches are gaining momentum to analyse a large variety of networks. Indeed, these approaches have demonstrated their efficiency for tasks such as community detection, node classification, and link prediction. However,…

Machine Learning · Computer Science 2021-01-06 Léo Pio-Lopez , Alberto Valdeolivas , Laurent Tichit , Élisabeth Remy , Anaïs Baudot

While rich medical datasets are hosted in hospitals distributed across the world, concerns on patients' privacy is a barrier against using such data to train deep neural networks (DNNs) for medical diagnostics. We propose Dopamine, a system…

Machine Learning · Computer Science 2021-02-01 Mohammad Malekzadeh , Burak Hasircioglu , Nitish Mital , Kunal Katarya , Mehmet Emre Ozfatura , Deniz Gündüz

In the rapidly evolving landscape of medical imaging diagnostics, achieving high accuracy while preserving computational efficiency remains a formidable challenge. This work presents \texttt{DeepMediX}, a groundbreaking, resource-efficient…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Kishore Babu Nampalle , Pradeep Singh , Uppala Vivek Narayan , Balasubramanian Raman

Double-strand DNA breaks (DSBs) are a form of DNA damage that can cause abnormal chromosomal rearrangements. Recent technologies based on high-throughput experiments have obvious high costs and technical challenges.Therefore, we design a…

Quantitative Methods · Quantitative Biology 2022-01-07 XU Wang , Huan Zhao , Weiwei TU , Hao Li , Yu Sun , Xiaochen Bo

Phishing attacks have inflicted substantial losses on individuals and businesses alike, necessitating the development of robust and efficient automated phishing detection approaches. Reference-based phishing detectors (RBPDs), which compare…

Cryptography and Security · Computer Science 2024-11-18 Yuexin Li , Chengyu Huang , Shumin Deng , Mei Lin Lock , Tri Cao , Nay Oo , Hoon Wei Lim , Bryan Hooi

Recent advances and achievements of artificial intelligence (AI) as well as deep and graph learning models have established their usefulness in biomedical applications, especially in drug-drug interactions (DDIs). DDIs refer to a change in…

Background. Fully automatic analysis of myocardial perfusion MRI datasets enables rapid and objective reporting of stress/rest studies in patients with suspected ischemic heart disease. Developing deep learning techniques that can analyze…

Change point detection is a commonly used technique in time series analysis, capturing the dynamic nature in which many real-world processes function. With the ever increasing troves of multivariate high-dimensional time series data,…

Computation · Statistics 2025-03-20 Martin Ondrus , Ivor Cribben

Identifying DNA- (DBPs) and RNA-binding proteins (RBPs) is crucial for the understanding of cell function, molecular interactions as well as regulatory functions. Owing to their high similarity, most of the existing approaches face…

Quantitative Methods · Quantitative Biology 2025-10-22 Nimisha Ghosh , Dheeran Sankaran , Rahul Balakrishnan Adhi , Sharath S , Amrut Anand

We propose a novel approach for RGB-D salient instance segmentation using a dual-branch cross-modal feature calibration architecture called CalibNet. Our method simultaneously calibrates depth and RGB features in the kernel and mask…

Computer Vision and Pattern Recognition · Computer Science 2024-06-12 Jialun Pei , Tao Jiang , He Tang , Nian Liu , Yueming Jin , Deng-Ping Fan , Pheng-Ann Heng

Virtual screening (VS) is an essential technique for understanding biomolecular interactions, particularly, drug design and discovery. The best-performing VS models depend vitally on three-dimensional (3D) structures, which are not…

Biomolecules · Quantitative Biology 2022-12-29 Li Shen , Hongsong Feng , Yuchi Qiu , Guo-Wei Wei

In this paper, we propose a novel system that integrates state-of-the-art, domain-specific large language models with advanced information retrieval techniques to deliver comprehensive and context-aware responses. Our approach facilitates…

Diffusion-weighted magnetic resonance imaging (dMRI) is widely used to assess the brain white matter. One of the most common computations in dMRI involves cross-subject tract-specific analysis, whereby dMRI-derived biomarkers are compared…

Image and Video Processing · Electrical Eng. & Systems 2023-07-12 Davood Karimi , Hamza Kebiri , Ali Gholipour

The computer-assisted radiologic informative report has received increasing research attention to facilitate diagnosis and treatment planning for dental care providers. However, manual interpretation of dental images is limited, expensive,…

Computer Vision and Pattern Recognition · Computer Science 2023-06-21 Amani Almalki , Longin Jan Latecki

The protein-protein interactions (PPIs) are crucial for understanding the majority of cellular processes. PPIs play important role in gene transcription regulation, cellular signaling, molecular basis of immune response and more. Moreover,…

Biomolecules · Quantitative Biology 2016-05-31 Maciej Pawel Ciemny , Mateusz Kurcinski , Andrzej Kolinski , Sebastian Kmiecik

The integration of deep learning approaches in biomedical research has been transformative, enabling breakthroughs in various applications. Despite these strides, its application in protein inference is impeded by the scarcity of…

Machine Learning · Computer Science 2026-05-07 Zheng Ma , Jiazhen Chen , Lei Xin , Ali Ghodsi

Decoding protein-protein interactions (PPIs) at the residue level is crucial for understanding cellular mechanisms and developing targeted therapeutics. We present Seq2Bind Webserver, a computational framework that leverages fine-tuned…

Quantitative Methods · Quantitative Biology 2025-06-18 Xiang Ma , Supantha Dey , Vaishnavey SR , Casey Zelinski , Qi Li , Ratul Chowdhury

Cheap high-throughput DNA sequencing may soon become routine not only for human genomes but also for practically anything requiring the identification of living organisms from their DNA: tracking of infectious agents, control of food…

Genomics · Quantitative Biology 2014-03-05 Laurent Gautier , Ole Lund

Retrieving the biological impacts of protein-protein interactions (PPIs) is essential for target identification (Target ID) in drug development. Given the vast number of proteins involved, this process remains time-consuming and…

Computation and Language · Computer Science 2025-06-02 Youngseung Jeon , Ziwen Li , Thomas Li , JiaSyuan Chang , Morteza Ziyadi , Xiang 'Anthony' Chen