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Survival analysis concerns the task of predicting the time until an event occurs. Often used in the medical field, survival analysis deals with incomplete (i.e., censored) data, for instance, from patients who did not experience the event…

Machine Learning · Computer Science 2026-05-29 Thalea Schlender , Peter A. N. Bosman , Tanja Alderliesten

Given overlapping subsets of a set of taxa (e.g. species), and posterior distributions on phylogenetic tree topologies for each of these taxon sets, how can we infer a posterior distribution on phylogenetic tree topologies for the entire…

Populations and Evolution · Quantitative Biology 2021-04-23 Michael Karcher , Cheng Zhang , Frederick A Matsen

There are several tools available to infer phylogenetic trees, which depict the evolutionary relationships among biological entities such as viral and bacterial strains in infectious outbreaks, or cancerous cells in tumor progression trees.…

Data Structures and Algorithms · Computer Science 2023-12-22 António Pedro Branco , Cátia Vaz , Alexandre P. Francisco

In this paper we introduce a continuous time stochastic neurite branching model closely related to the discrete time stochastic BES-model. The discrete time BES-model is underlying current attempts to simulate cortical development, but is…

Neurons and Cognition · Quantitative Biology 2015-03-17 Ronald A. J. van Elburg

Homogeneous fragmentations describe the evolution of a unit mass that breaks down randomly into pieces as time passes. They can be thought of as continuous time analogs of a certain type of branching random walks, which suggests the use of…

Probability · Mathematics 2007-05-23 Jean Bertoin , Alain Rouault

Rooted and ranked binary trees are mathematical objects of great importance used to model hierarchical data and evolutionary relationships with applications in many fields including evolutionary biology and genetic epidemiology. Bayesian…

Methodology · Statistics 2021-06-08 Samyak Rajanala , Julia A. Palacios

Stochastic branching processes are a classical model for describing random trees, which have applications in numerous fields including biology, physics, and natural language processing. In particular, they have recently been proposed to…

Logic in Computer Science · Computer Science 2012-06-07 Taolue Chen , Klaus Dräger , Stefan Kiefer

The standard approach to estimate species trees is to align a selected set of genes, concatenate the alignments and then estimate a consensus tree. However, individual genes contain differing levels of evolutionary information, either…

Populations and Evolution · Quantitative Biology 2021-11-29 Ali Amiryousefi

We investigate vertex levels of containment in a random hypergraph grown in the spirit of a recursive tree. We consider a local profile tracking the evolution of the containment of a particular vertex over time, and a global profile…

Probability · Mathematics 2021-01-19 Joshua Sparks , Srinivasan Balaji , Hosam Mahmoud

Variation in the evolutionary process across the sites of nucleotide sequence alignments is well established, and is an increasingly pervasive feature of datasets composed of gene regions sampled from multiple loci and/or different genomes.…

Populations and Evolution · Quantitative Biology 2014-09-04 Brian R. Moore , Jim McGuire , Fredrik Ronquist , John P. Huelsenbeck

In phylogenetics, evolution is traditionally represented in a tree-like manner. However, phylogenetic networks can be more appropriate for representing evolutionary events such as hybridization, horizontal gene transfer, and others. In…

Data Structures and Algorithms · Computer Science 2024-10-18 Manuel Lafond , Vincent Moulton

This article analyzes the problem of estimating the time until an event occurs, also known as survival modeling. We observe through substantial experiments on large real-world datasets and use-cases that populations are largely…

Machine Learning · Computer Science 2019-05-13 David Hubbard , Benoit Rostykus , Yves Raimond , Tony Jebara

We study self-similarity in random binary rooted trees. In a well-understood case of Galton-Watson trees, a distribution on a space of trees is said to be self-similar if it is invariant with respect to the operation of pruning, which cuts…

Probability · Mathematics 2018-08-14 Yevgeniy Kovchegov , Ilya Zaliapin

The Yule model and the coalescent model are two neutral stochastic models for generating trees in phylogenetics and population genetics, respectively. Although these models are quite different, they lead to identical distributions…

Populations and Evolution · Quantitative Biology 2015-03-17 Sha Zhu , James H. Degnan , Mike Steel

Diversification is nested, and early models suggested this could lead to a great deal of evolutionary redundancy in the Tree of Life. This result is based on a particular set of branch lengths produced by the common coalescent, where…

Populations and Evolution · Quantitative Biology 2011-08-02 Arne Mooers , Olivier Gascuel , Tanja Stadler , Heyang Li , Mike Steel

Mast fruiting represents a synchronous population behaviour which can spread on large landscape areas. This reproductive pattern is generally perceived as a synchronous periodic production of large seed crops and has a significant practical…

Quantitative Methods · Quantitative Biology 2016-02-12 Ciprian Palaghianu , Marian Dragoi

Stochastic modeling of phylogenies raises five questions that have received varying levels of attention from quantitatively inclined biologists. 1) How large do we expect (from the model) the ration of maximum historical diversity to…

Populations and Evolution · Quantitative Biology 2013-02-07 Lea Popovic , Maxim Krikun , David Aldous

In this work, we develop a stochastic model of gene gain and loss with the aim of inferring when (if at all) in evolutionary history and association between two genes arises. The data we consider is a species tree along with information on…

Populations and Evolution · Quantitative Biology 2023-09-07 Jiahao Diao , Malgorzata M. O'Reilly , Barbara R. Holland

Rooted phylogenetic networks are used to describe evolutionary histories that contain non-treelike evolutionary events such as hybridization and horizontal gene transfer. In some cases, such histories can be described by a phylogenetic…

Populations and Evolution · Quantitative Biology 2016-10-03 Laura Jetten , Leo van Iersel

Survival analysis of right censored data arises often in many areas of research including medical research. Effect of covariates (and their interactions) on survival distribution can be studied through existing methods which requires to…

Methodology · Statistics 2021-08-11 Madan Gopal Kundu , Samiran Ghosh