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Related papers: L\'{e}vy-based growth models

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In this study, we model avascular tumour growth in epithelial tissue. This can help us to get a macroscopic view of the interaction between the tumour with its surrounding microenvironment and the physical changes within the tumour…

Tissues and Organs · Quantitative Biology 2019-05-15 Sounak Sadhukhan , S. K. Basu

The paper examines stochastic diffusion within an expanding space-time framework. It starts with providing a rationale for the considered model and its motivation from cosmology where the expansion of space-time is used in modelling various…

Probability · Mathematics 2023-12-22 Philip Broadbridge , Illia Donhauzer , Andriy Olenko

During the last decades, medical observations and multiscale data concerning tumor growth are mounting. At the same time, contemporary imaging techniques well established in clinical practice, provide a variety of information on real-time,…

Tissues and Organs · Quantitative Biology 2017-12-11 Markos Antonopoulos , Georgios Stamatakos

We propose a unified stochastic SIR model driven by L\'{e}vy noise. The model is structural enough to allow for time-dependency, nonlinearity, discontinuity, demography and environmental disturbances. We present concise results on the…

Probability · Mathematics 2024-03-06 Terry Easlick , Wei Sun

We develop a method that relates the truncated cumulant-function of the fourth order with the L\'evian cumulant-function. This gives us explicit formulas for the L\'evy-parameters, which allow a real-time analysis of the state of a…

Statistical Mechanics · Physics 2019-12-04 Alexander Jurisch

In the present article the diffusion equation is used to model the spatio-temporal dynamics of a tumor, taking into account the heterogeneous of the medium. This approach makes it possible to take into account the complex geometric shape of…

Biological Physics · Physics 2023-02-07 Maxim V. Polyakov , Valeria V. Ten

Modelling randomness in shape data, for example, the evolution of shapes of organisms in biology, requires stochastic models of shapes. This paper presents a new stochastic shape model based on a description of shapes as functions in a…

Computer Vision and Pattern Recognition · Computer Science 2023-02-13 Elizabeth Baker , Thomas Besnier , Stefan Sommer

We study the spatial evolutionary dynamics of solid tumors as they obtain additional driver mutations. We start with a cancer clone that expands uniformly in three dimensions giving rise to a spherical shape. We assume that cell division…

Populations and Evolution · Quantitative Biology 2013-08-08 Tibor Antal , P. L. Krapivsky , M. A. Nowak

We present a general class of spatio-temporal stochastic processes describing the causal evolution of a positive-valued field in space and time. The field construction is based on independently scattered random measures of Levy type whose…

Mathematical Physics · Physics 2007-05-23 J. Schmiegel , O. E. Barndorff-Nielsen , H. C. Eggers

Gaussian random fields with Mat\'ern covariance functions are popular models in spatial statistics and machine learning. In this work, we develop a spatio-temporal extension of the Gaussian Mat\'ern fields formulated as solutions to a…

Methodology · Statistics 2023-04-06 Finn Lindgren , Haakon Bakka , David Bolin , Elias Krainski , Håvard Rue

Existing approaches to modeling the dynamics of brain tumor growth, specifically glioma, employ biologically inspired models of cell diffusion, using image data to estimate the associated parameters. In this work, we propose an alternative…

In this paper, a two-dimensional model for the growth of multi-layer tumors is presented. The model consists of a free boundary problem for the tumor cell membrane and the tumor is supposed to grow or shrink due to cell proliferation or…

Analysis of PDEs · Mathematics 2013-06-11 Martin Kohlmann

Stochastic Spatio-Temporal processes are prevalent across domains ranging from modeling of plasma to the turbulence in fluids to the wave function of quantum systems. This letter studies a measure-theoretic description of such systems by…

Optimization and Control · Mathematics 2021-05-25 George I. Boutselis , Ethan N. Evans , Marcus A. Pereira , Evangelos A. Theodorou

The problem of the onset and growth of solid tumour in homogeneous tissue is regarded using an approach based on local interaction between the tumoral and the sane tissue cells. The characteristic sizes and growth rates of spherical…

Cell Behavior · Quantitative Biology 2007-05-23 R. G. Khlebopros , V. A. Slepkov , V. G. Sukhovolsky , Y. V. Mironov , V. E. Fedorov , S. P. Gabuda

Growth-fragmentation processes describe systems of particles in which each particle may grow larger or smaller, and divide into smaller ones as time proceeds. Unlike previous studies, which have focused mainly on the self-similar case, we…

Probability · Mathematics 2020-02-05 Quan Shi

We give a very short introduction to discrete and continuum models for the evolutionary and spatial dynamics of cancer through two case studies: a model for the evolutionary dynamics of cancer cells under cytotoxic therapy and a model for…

Tissues and Organs · Quantitative Biology 2019-11-07 Tommaso Lorenzi , Fiona R. Macfarlane , Chiara Villa

We investigate avascular tumour growth as a two-phase process consisting of cells and liquid. Based on the one-dimensional continuum moving-boundary model formulated by (Byrne, King, McElwain, Preziosi, Applied Mathematics Letters, 2003,…

Analysis of PDEs · Mathematics 2020-06-24 Andrea Genovese de Oliveira , John R. King

Circular data arise in many areas of application. Recently, there has been interest in looking at circular data collected separately over time and over space. Here, we extend some of this work to the spatio-temporal setting, introducing…

Methodology · Statistics 2017-04-18 Gianluca Mastrantonio , Giovanna Jona Lasinio , Alan E. Gelfand

In this paper we present a method for estimating unknown parameters that appear on an avascular, spheric tumour growth model. The model for the tumour is based on nutrient driven growth of a continuum of live cells, whose birth and death…

Mathematical Physics · Physics 2012-09-14 D. A. Knopoff , D. R. Fernández , G. A. Torres , C. V. Turner

We model non-stationary volume-price distributions with a log-normal distribution and collect the time series of its two parameters. The time series of the two parameters are shown to be stationary and Markov-like and consequently can be…

Statistical Finance · Quantitative Finance 2017-05-04 Joana Estevens , Paulo Rocha , Joao Boto , Pedro Lind