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We have analyzed the relations between the mutational pressure, recombination and selection pressure in the bit-string model with sexual reproduction. For specific sets of these parameters we have found three phase transitions with one…

Populations and Evolution · Quantitative Biology 2007-05-23 D. Stauffer , S. Cebrat

We study numerically a disordered version of the model for DNA denaturation transition (DSAW-DNA) consisting of two interacting SAWs in 3d, which undergoes a first order transition in the homogeneous case. The two possible values eAT and…

Soft Condensed Matter · Physics 2009-11-11 Barbara Coluzzi

We give a closed form of the discrete-time evolution of a recombination transformation in population genetics. This decomposition allows to define a Markov chain in a natural way. We describe the geometric decay rate to the limit…

Probability · Mathematics 2016-03-24 Servet Martinez

We present the first results from a Bayesian analysis of the WMAP first year data using a Gibbs sampling technique. Using two independent, parallel supercomputer codes we analyze the WMAP Q, V and W bands. The analysis results in a full…

New results on the anisotropy of the cosmic microwave background (CMB) and its polarization based on the first 3 years of data from the Wilkinson Microwave Anisotropy Probe (WMAP) have revised the electron scattering optical depth downward…

Astrophysics · Physics 2009-11-11 Marcelo A. Alvarez , Paul R. Shapiro , Kyungjin Ahn , Ilian T. Iliev

The accuracy of the recombination estimation method of Padhukasahasram et al. 2006 can be improved by including additional informative summary statistics in the rejection scheme and by simulating datasets under a fixed segregating sites…

Genomics · Quantitative Biology 2012-03-27 Badri Padhukasahasram

Calculations of cosmological hydrogen recombination are vital for the extraction of cosmological parameters from cosmic microwave background (CMB) observations, and for imposing constraints to inflation and re-ionization. The Planck}…

Cosmology and Nongalactic Astrophysics · Physics 2010-04-22 Daniel Grin , Christopher M. Hirata

In large populations, multiple beneficial mutations may be simultaneously spreading. In asexual populations, these mutations must either arise on the same background or compete against each other. In sexual populations, recombination can…

Populations and Evolution · Quantitative Biology 2013-12-19 D. B. Weissman , O. Hallatschek

We report on the status of primordial nucleosynthesis in light of recent results on CMB anisotropies from WMAP experiment. Theoretical estimates for nuclei abundances, along with the corresponding uncertainties, are evaluated using a new…

Astrophysics · Physics 2009-11-10 A. Cuoco , F. Iocco , G. Mangano , G. Miele , O. Pisanti , P. D. Serpico

Genome rearrangements are evolutionary events that shuffle genomic architectures. Most frequent genome rearrangements are reversals, translocations, fusions, and fissions. While there are some more complex genome rearrangements such as…

Genomics · Quantitative Biology 2015-04-07 Nikita Alexeev , Rustem Aidagulov , Max A. Alekseyev

We propose a genetic algorithm (GA) for hyperparameter optimization of artificial neural networks which includes chromosomal crossover as well as a decoupling of parameters (i.e., weights and biases) from hyperparameters (e.g., learning…

Neural and Evolutionary Computing · Computer Science 2019-01-15 Aaron Vose , Jacob Balma , Alex Heye , Alessandro Rigazzi , Charles Siegel , Diana Moise , Benjamin Robbins , Rangan Sukumar

We extend the spatial $\Lambda$-Fleming-Viot process introduced in [Electron. J. Probab. 15 (2010) 162-216] to incorporate recombination. The process models allele frequencies in a population which is distributed over the two-dimensional…

Probability · Mathematics 2012-11-28 A. M. Etheridge , A. Véber

The analysis of intermittent data is improved. The standard method of recovering the history of a particle cascade is proved in general not to reproduce the structure of the true cascade. The recovering corrections to the standard method…

High Energy Physics - Phenomenology · Physics 2011-09-13 B. Ziaja

Mutations can arise from the chance misincorporation of nucleotides during DNA replication or from DNA lesions that are not repaired correctly. We introduce a model that relates the source of mutations to their accumulation with cell…

Populations and Evolution · Quantitative Biology 2015-07-27 Ziyue Gao , Minyoung J. Wyman , Guy Sella , Molly Przeworski

We study decomposable combinatorial labeled structures in the exp-log class, specifically, two examples of type a=1 and two examples of type a=1/2. Our approach is to establish how well existing theory matches experimental data. For…

Combinatorics · Mathematics 2022-01-25 Steven Finch

The Moran model with recombination is considered, which describes the evolution of the genetic composition of a population under recombination and resampling. There are $n$ sites (or loci), a finite number of letters (or alleles) at every…

Probability · Mathematics 2018-11-01 Mareike Esser , Sebastian Probst , Ellen Baake

With the development of machine learning and Big Data, the concepts of linear and non-linear optimization techniques are becoming increasingly valuable for many quantitative disciplines. Problems of that nature are typically solved using…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-06-21 Wiktor Maj

We construct the non-linear Markov process connected with biological model of bacterial genome recombination. The description of invariant measures of this process gives us the solution of one problem in elementary probability theory.

Probability · Mathematics 2015-06-22 Arseniy V. Akopyan , Sergey A. Pirogov , Aleksandr N. Rybko

In this paper, we propose a linear representation of BCJR maximum a posteriori probability (MAP) decoding of a rate 1/2 convolutional code (CC), referred to as the linear MAP decoding (LMAP). We discover that the MAP forward and backward…

Information Theory · Computer Science 2025-04-22 Yonghui Li , Chentao Yue , Branka Vucetic

Variable continuum emission from AGN can be used to probe the structure of their accretion disks via reverberation mapping. Assuming a variable, hot inner light source irradiates the surrounding accretion disk, time delays between different…