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Increasing attention has been recently devoted to protein-based nanobiosensors. The main reason is the huge number of possible technological applications, going from drug detection to cancer early diagnosis. Their operating model is based…

Mesoscale and Nanoscale Physics · Physics 2011-07-15 Eleonora Alfinito , Jean-Francois Millithaler , Lino Reggiani , Nadia Zine , Nicole Jaffrezic-Renault

In this paper we explore relevant electrical properties of two olfactory receptors (ORs), one from rat OR I7 and the other from human OR 17-40, which are of interest for the realization of smell nanobiosensors. The investigation compares…

Soft Condensed Matter · Physics 2015-05-27 E. Alfinito , J. -F. Millithaler , L. Reggiani

The olfactory sense measures the chemical composition of the environment using a diverse array of olfactory receptors. In vertebrates, the olfactory receptors reside in a mucus layer in the nasal cavity and can thus only detect odorants…

Biological Physics · Physics 2023-01-25 Swati Sen , David Zwicker

Nanoparticle-based fluorescent sensors have emerged as a competitive alternative to small molecule sensors, due to their excellent fluorescence-based sensing capabilities. The tailorability of design, architecture, and photophysical…

Applied Physics · Physics 2020-05-19 Anil Chandra , Saumya Prasad , Giuseppe Gigli , Loretta L. del Mercato

Our sense of smell relies on sensitive, selective atomic-scale processes that are initiated when a scent molecule meets specific receptors in the nose. However, the physical mechanisms of detection are not clear. While odorant shape and…

Biological Physics · Physics 2015-06-26 Jennifer C. Brookes , Filio Hartoutsiou , A. P. Horsfield , A. M. Stoneham

We describe a system for interrogating the acoustic properties of sub-nanoliter liquid samples within an open microfluidics platform. Sessile droplets were deposited onto integrated optomechanical sensors, which possess…

Applied Physics · Physics 2023-07-17 Kyle G. Scheuer , Franz B. Romero , Graham J. Hornig , Ray G. DeCorby

Micro and nanoscale particles are crucial in various fields, from biomedical imaging to environmental processes. While conventional spectroscopy and microscopy methods for characterizing these particles often involve bulky equipment and…

Biological Physics · Physics 2024-11-26 Jie Liao , Maxwell Adolphson , Hangyue Li , Dipayon Kumar Sikder , Chenyang Lu , Lan Yang

Olfaction lies at the intersection of chemical structure, neural encoding, and linguistic perception, yet existing representation methods fail to fully capture this pathway. Current approaches typically model only isolated segments of the…

Computation and Language · Computer Science 2026-04-21 Yanyi Su , Hongshuai Wang , Zhifeng Gao , Jun Cheng

Biomonitoring wearable sensors based on two-dimensional nanomaterials have lately elicited keen research interest and potential for a new range of flexible nanoelectronic devices. Practical nanomaterial-based devices suited for real-world…

A design concept for nanowire-based sensors and arrays is described. The fabrication technique involves electrodeposition to directly grow nanowires between patterned thin film contact electrodes. To prove our concept, we have…

Materials Science · Physics 2009-11-10 Minhee Yun , Nosang V. Myung , Richard P. Vasquez , Jianjun Wang , Harold Monbouquette

Animals have evolved to rapidly detect and recognise brief and intermittent encounters with odour packages, exhibiting recognition capabilities within milliseconds. Artificial olfaction has faced challenges in achieving comparable results…

Nanophotonics has become a key enabling technology in biomedicine with great promises in early diagnosis and less invasive therapies. In this context, the unique capability of plasmonic noble metal nanoparticles to concentrate light on the…

Applied Physics · Physics 2017-08-02 Ozlem Yavas , Mikael Svedendahl , Paulina Dobosz , Vanesa Sanz , Romain Quidant

Magnetic nanostructures sustaining different kinds of optical modes have been used for magnetometry and label-free ultrasensitive refractive index probing, where the main challenge is the realization of compact devices able to transfer this…

In this study, we explore how the combination of synthetic biology, neuroscience modeling, and neuromorphic electronic systems offers a new approach to creating an artificial system that mimics the natural sense of smell. We argue that a…

Neural and Evolutionary Computing · Computer Science 2025-08-04 Kevin Max , Larissa Sames , Shimeng Ye , Jan Steinkühler , Federico Corradi

Odor identification is an important area in a wide range of industries like cosmetics, food, beverages and medical diagnosis among others. Odor detection could be done through an array of gas sensors conformed as an electronic nose where a…

Machine Learning · Computer Science 2019-05-06 Jose de Jesus Rubio , Ramon Silva Ortigoza , Francisco Jacob Avila , Adolfo Melendez , Juan Manuel Stein

A novel nanostructured electrochemical immunsensor for the determination of progesterone is reported. The approach combines the properties of gold nanoparticles with the use of a graphite-Teflon composite electrode matrix, into which gold…

Materials Science · Physics 2007-08-13 J. -M. Pingarron , P. Yanez-Sedeno , A. Gonzalez-Cortes , V. Carralero

Ultrasensitive optical detection of nanometer-scaled particles is highly desirable for applications in early-stage diagnosis of human diseases, environmental monitoring, and homeland security, but remains extremely difficult due to ultralow…

Optical biosensors are indispensable in medical and environmental diagnostics, yet existing approaches are fundamentally limited in their sensitivity due to ensemble-averaged measurements. Digital biosensing has emerged as a promising…

Cell-based biosensors constitute a fundamental tool in biotechnology, and their relevance has greatly increased in recent years as a result of a surging demand for reduced animal testing and for high-throughput and cost-effective in vitro…

Before aerosols can be sensed, sampling technologies must capture the particulate matter of interest. To that end, for systems deployed in open environments where the location of the aerosol is unknown, extending the reach of the sampler…

Systems and Control · Electrical Eng. & Systems 2025-05-26 Yahya Naveed , Julia Gersey , Pei Zhang
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