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An important open question in computational neuroscience is how various spatially tuned neurons, such as place cells, are used to support the learning of reward-seeking behavior of an animal. Existing computational models either lack…

Neurons and Cognition · Quantitative Biology 2022-05-18 Yuanxiang Gao

We present a comprehensive study of the photon energy ($h \nu$) dependent line-shape evolution of molecular orbital signals of large $\pi$-conjugated molecules by resonant photoelectron spectroscopy (RPES). A comparison to RPES data of…

Materials Science · Physics 2014-02-19 Christoph Sauer , Michael Wießner , Achim Schöll , Friedrich Reinert

The ubiquity of topographic maps in the brain has long been known, and molecular mechanisms for the formation of topographic organization of neural systems have been revealed. Less attention has been given to the question of why are the…

Neurons and Cognition · Quantitative Biology 2018-11-13 Shigeko Takahashi

The evolution of electron correlation in Sr$_{x}$Ca$_{1-x}$VO$_3$ has been studied using a combination of bulk-sensitive resonant soft x-ray emission spectroscopy (RXES), surface-sensitive photoemission spectroscopy (PES), and ab initio…

Strongly Correlated Electrons · Physics 2013-07-25 J. Laverock , B. Chen , K. E. Smith , R. P. Singh , G. Balakrishnan , M. Gu , J. W. Lu , S. A. Wolf , R. M. Qiao , W. Yang , J. Adell

While modern structural biology has provided us with a rich and diverse picture of membrane proteins, the biological function of membrane proteins is often influenced by the mechanical properties of the surrounding lipid bilayer. Here we…

Biomolecules · Quantitative Biology 2013-05-27 Christoph A. Haselwandter , Rob Phillips

Interplay of magnetism and electronic band topology in unconventional magnets enables the creation and fine control of novel electronic phenomena. In this work, we use scanning tunneling microscopy and spectroscopy to study thin films of a…

While the ultrastructure of the myelin has been considered to be a quasi-crystalline stable system, nowadays its multiscale complex dynamics appears to play a key role for its functionality, degeneration and repair processes following…

Quantitative Methods · Quantitative Biology 2017-09-20 Michael Di Gioacchino , Gaetano Campi , Nicola Poccia , Antonio Bianconi

The state-of-the art machine learning approach to training deep neural networks, backpropagation, is implausible for real neural networks: neurons need to know their outgoing weights; training alternates between a bottom-up forward pass…

Machine Learning · Computer Science 2020-10-26 Roman Pogodin , Peter E. Latham

Motion tracking is a challenge the visual system has to solve by reading out the retinal population. Here we recorded a large population of ganglion cells in a dense patch of salamander and guinea pig retinas while displaying a bar moving…

Neurons and Cognition · Quantitative Biology 2016-02-17 Olivier Marre , Vicente Botella-Soler , Kristina D. Simmons , Thierry Mora , Gašper Tkačik , Michael J. Berry

Topology transcends boundaries that conventionally delineate physical, biological and engineering sciences. Our ability to mathematically describe topology, combined with our access to precision tracking and manipulation approaches, has…

Biological Physics · Physics 2021-01-01 Anupam Sengupta

We study analytically and numerically spin effects in MoS_2 monolayer armchair quantum wires and quantum dots. The interplay between intrinsic and Rashba spin orbit interactions induced by an electric field leads to helical modes, giving…

Mesoscale and Nanoscale Physics · Physics 2013-08-07 Jelena Klinovaja , Daniel Loss

In the study of neurons, morphology influences function. The complexity in the structure of neurons poses a challenge in the identification and analysis of similar and dissimilar neuronal cells. Existing methodologies carry out structural…

Image and Video Processing · Electrical Eng. & Systems 2018-02-21 Tamal Batabyal , Scott T. Acton

Fully Convolutional Networks have been achieving remarkable results in image semantic segmentation, while being efficient. Such efficiency results from the capability of segmenting several voxels in a single forward pass. So, there is a…

Computer Vision and Pattern Recognition · Computer Science 2020-06-22 Sergio Pereira , Adriano Pinto , Joana Amorim , Alexandrine Ribeiro , Victor Alves , Carlos A. Silva

Memristors have been suggested as neuromorphic computing elements. Spike-time dependent plasticity and the Hodgkin-Huxley model of the neuron have both been modelled effectively by memristor theory. The d.c. response of the memristor is a…

Emerging Technologies · Computer Science 2014-02-18 Deborah Gater , Attya Iqbal , Jeffrey Davey , Ella Gale

It is well known that carefully crafted imperceptible perturbations can cause state-of-the-art deep learning classification models to misclassify. Understanding and analyzing these adversarial perturbations play a crucial role in the design…

Image and Video Processing · Electrical Eng. & Systems 2023-08-08 P Charantej Reddy , Aditya Siripuram , Sumohana S. Channappayya

As next-generation implantable brain-machine interfaces become pervasive on edge device, incrementally learning new tasks in bio-plasticity ways is urgently demanded for Neuromorphic chips. Due to the inherent characteristics of its…

Emerging Technologies · Computer Science 2023-12-01 Zifan Ning , Chaojin Chen , Xiang Cheng , Wangzi Yao , Tielin Zhang , Bo Xu

In common real-world robotic operations, action and state spaces can be vast and sometimes unknown, and observations are often relatively sparse. How do we learn the full topology of action and state spaces when given only few and sparse…

Machine Learning · Computer Science 2019-07-16 Lingzhi Zhang , Andong Cao , Rui Li , Jianbo Shi

Anatomic connections between brain areas affect information flow between neuronal circuits and the synchronization of neuronal activity. However, such structural connectivity does not coincide with effective connectivity, related to the…

Neurons and Cognition · Quantitative Biology 2015-06-03 Demian Battaglia , Annette Witt , Fred Wolf , Theo Geisel

A structural genetic model incorporating a modern understanding of the genome and common practice in genome-wide association studies is derived mathematically. The model shows the Haldane map distance as a direct consequence of the…

Genomics · Quantitative Biology 2022-05-24 Christopher Salahub

In this paper, we derive a new model of synaptic plasticity, based on recent algorithms for reinforcement learning (in which an agent attempts to learn appropriate actions to maximize its long-term average reward). We show that these direct…

Machine Learning · Computer Science 2019-11-19 Peter L. Bartlett , Jonathan Baxter