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Complex diseases can be modeled as damage to intracellular networks that results in abnormal cell behaviors. Network-based dynamic models such as Boolean models have been employed to model a variety of biological systems including those…

Biological Physics · Physics 2016-12-30 Gang Yang , Colin Campbell , Réka Albert

Maintaining the ability to fire sparsely is crucial for information encoding in neural networks. Additionally, spiking homeostasis is vital for spiking neural networks with changing numbers of weights and neurons. We discuss a range of…

Neural and Evolutionary Computing · Computer Science 2019-10-02 Katarzyna Kozdon , Peter Bentley

We study a mechanism of activity sustaining on networks inspired by a well-known model of neuronal dynamics. Our primary focus is the emergence of self-sustaining collective activity patterns, where no single node can stay active by itself,…

Physics and Society · Physics 2017-12-27 A. E. Allahverdyan , G. Ver Steeg , A. Galstyan

Deep feedforward and recurrent rate-based neural networks have become successful functional models of the brain, but they neglect obvious biological details such as spikes and Dale's law. Here we argue that these details are crucial in…

Neurons and Cognition · Quantitative Biology 2023-12-29 William F. Podlaski , Christian K. Machens

The mechanisms responsible for contention of activity in systems represented by networks are crucial in various phenomena, as in diseases such as epilepsy that affects the neuronal networks, and for information dissemination in social…

Biological Physics · Physics 2013-02-20 Diego R. Amancio , Osvaldo N. Oliveira , Luciano da F. Costa

Starting from a spectral expansion of the Fokker-Plank equation for the membrane potential density in a network of spiking neurons, a low-dimensional dynamics of the collective firing rate is derived. As a result a $n$-order ordinary…

Neurons and Cognition · Quantitative Biology 2016-09-29 Maurizio Mattia

Neural network dynamics emerge from the interaction of spiking cells. One way to formulate the problem is through a theoretical framework inspired by ideas coming from statistical physics, the so-called mean-field theory. In this document,…

Analysis of PDEs · Mathematics 2020-11-11 Grégory Dumont , Pierre Gabriel

We study the spike statistics of neurons in a network with dynamically balanced excitation and inhibition. Our model, intended to represent a generic cortical column, comprises randomly connected excitatory and inhibitory leaky…

Neurons and Cognition · Quantitative Biology 2007-05-23 Alexander Lerchner , Cristina Ursta , John Hertz , Mandana Ahmadi , Pauline Ruffiot

Brain network is remarkably cost-efficient while the fundamental physical and dynamical mechanisms underlying its economical optimization in network structure and activity are not clear. Here we study intricate cost-efficient interplay…

Biological Physics · Physics 2021-06-21 Junhao Liang , Sheng-Jun Wang , Changsong Zhou

A synfire chain is a network that can generate repeated spike patterns with millisecond precision. Although synfire chains with only one activity propagation mode have been intensively analyzed with several neuron models, those with several…

Neurons and Cognition · Quantitative Biology 2009-11-13 Kazuya Ishibashi , Kosuke Hamaguchi , Masato Okada

The steady-state firing rate and firing-rate response of the leaky and exponential integrate-and-fire models receiving synaptic shot noise with excitatory and inhibitory reversal potentials is examined. For the particular case where the…

Neurons and Cognition · Quantitative Biology 2024-03-13 Magnus J E Richardson

The ability to understand and eventually predict the emergence of information and activation cascades in social networks is core to complex socio-technical systems research. However, the complexity of social interactions makes this a…

Physics and Society · Physics 2015-06-16 Pablo Piedrahíta , Javier Borge-Holthoefer , Yamir Moreno , Alex Arenas

Electrical coupling between neurons is broadly present across brain areas and is typically assumed to synchronize network activity. However, intrinsic properties of the coupled cells can complicate this simple picture. Many cell types with…

Adaptation and Self-Organizing Systems · Physics 2018-01-19 Thomas Chartrand , Mark S. Goldman , Timothy J. Lewis

We show that in model neuronal cultures, where the probability of interneuronal connection formation decreases exponentially with increasing distance between the neurons, there exists a small number of spatial nucleation centers of a…

Neurons and Cognition · Quantitative Biology 2018-11-09 A. V. Paraskevov , D. K. Zendrikov

We address the problem of identifying functional interactions among stochastic neurons with variable-length memory from their spiking activity. The neuronal network is modeled by a stochastic system of interacting point processes with…

Applications · Statistics 2025-07-01 Ricardo F. Ferreira , Matheus E. Pacola , Vitor G. Schiavone , Rodrigo F. O. Pena

The combination of new recording techniques in neuroscience and powerful inference methods recently held the promise to recover useful effective models, at the single neuron or network level, directly from observed data. The value of a…

Neurons and Cognition · Quantitative Biology 2018-04-09 Cristiano Capone , Guido Gigante , Paolo Del Giudice

Nonlinear dynamics of spiking neural networks has recently attracted much interest as an approach to understand possible information processing in the brain and apply it to artificial intelligence. Since information can be processed by…

Confinement is a ubiquitous mechanism in nature, whereby particles feel an attractive force that increases without bound as they separate. A prominent example is color confinement in particle physics, in which baryons and mesons are…

Recent work emphasizes that the maximum entropy principle provides a bridge between statistical mechanics models for collective behavior in neural networks and experiments on networks of real neurons. Most of this work has focused on…

Neurons and Cognition · Quantitative Biology 2015-06-05 Gasper Tkacik , Olivier Marre , Thierry Mora , Dario Amodei , Michael J. Berry , William Bialek

Experimental characterization of neuronal dynamics involves recording both of spontaneous activity patterns and of responses to transient and sustained inputs. While much theoretical attention has been devoted to the spontaneous activity of…

Neurons and Cognition · Quantitative Biology 2020-07-24 Jonathan Rubin , Justyna Signerska-Rynkowska , Jonathan D. Touboul
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