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How the architecture of gene regulatory networks ultimately shapes gene expression patterns is an open question, which has been approached from a multitude of angles. The dominant strategy has been to identify non-random features in these…

Molecular Networks · Quantitative Biology 2023-07-19 Dzmitry Rumiantsau , Annick Lesne , Marc-Thorsten Hütt

Recent studies have been using graph theoretical approaches to model complex networks (such as social, infrastructural or biological networks), and how their hardwired circuitry relates to their dynamic evolution in time. Understanding how…

Neurons and Cognition · Quantitative Biology 2015-07-17 Anca Radulescu

Boolean networks have been used successfully in modeling biological networks and provide a good framework for theoretical analysis. However, the analysis of large networks is not trivial. In order to simplify the analysis of such networks,…

Molecular Networks · Quantitative Biology 2013-11-29 Alan Veliz-Cuba , Reinhard Laubenbacher , Boris Aguilar

This short paper presents an abstract, tunable model of genomic structural change within the cell lifecycle and explores its use with simulated evolution. A well-known Boolean model of genetic regulatory networks is extended to include…

Computational Engineering, Finance, and Science · Computer Science 2012-01-18 Larry Bull

Networks with nodes embedded in a metric space have gained increasing interest in recent years. The effects of spatial embedding on the networks' structural characteristics, however, are rarely taken into account when studying their…

Physics and Society · Physics 2016-07-06 Marc Wiedermann , Jonathan F. Donges , Jürgen Kurths , Reik V. Donner

The low-dimensional manifold hypothesis posits that the data found in many applications, such as those involving natural images, lie (approximately) on low-dimensional manifolds embedded in a high-dimensional Euclidean space. In this…

Machine Learning · Computer Science 2023-02-07 Juncai He , Richard Tsai , Rachel Ward

In the study of dynamical systems on networks/graphs, a key theme is how the network topology influences stability for steady states or synchronized states. Ideally, one would like to derive conditions for stability or instability that…

Dynamical Systems · Mathematics 2020-07-01 Raffaella Mulas , Christian Kuehn , Jürgen Jost

In this paper we study the dynamical behavior of Boolean networks with firing memory, namely Boolean networks whose vertices are updated synchronously depending on their proper Boolean local transition functions so that each vertex remains…

Discrete Mathematics · Computer Science 2022-04-25 Eric Goles , Fabiola Lobos , Gonzalo A. Ruz , Sylvain Sené

Many material response functions depend strongly on microstructure, such as inhomogeneities in phase or orientation. Homogenization presents the task of predicting the mean response of a sample of the microstructure to external loading for…

Machine Learning · Computer Science 2022-10-04 Reese Jones , Cosmin Safta , Ari Frankel

We consider the problem of embedding a dynamic network, to obtain time-evolving vector representations of each node, which can then be used to describe changes in behaviour of individual nodes, communities, or the entire graph. Given this…

Machine Learning · Statistics 2022-01-21 Ian Gallagher , Andrew Jones , Patrick Rubin-Delanchy

Classical network embeddings create a low dimensional representation of the learned relationships between features across nodes. Such embeddings are important for tasks such as link prediction and node classification. In the current paper,…

Artificial Intelligence · Computer Science 2021-03-15 Chris Connell , Yang Wang

Many knowledge graph embedding methods operate on triples and are therefore implicitly limited by a very local view of the entire knowledge graph. We present a new framework MOHONE to effectively model higher order network effects in…

Computation and Language · Computer Science 2018-11-02 Hao Yu , Vivek Kulkarni , William Wang

Graph neural networks (GNNs) have significantly improved the representation power for graph-structured data. Despite of the recent success of GNNs, the graph convolution in most GNNs have two limitations. Since the graph convolution is…

Machine Learning · Computer Science 2021-12-30 Jinyoung Park , Sungdong Yoo , Jihwan Park , Hyunwoo J. Kim

We analyse a model of fixed in-degree Random Boolean Networks in which the fraction of input-receiving nodes is controlled by a parameter gamma. We investigate analytically and numerically the dynamics of graphs under a parallel XOR…

Statistical Mechanics · Physics 2009-09-03 L. Ciandrini , C. Maffi , A. Motta , B. Bassetti , M. Cosentino Lagomarsino

In automata networks, it is well known that the way entities update their states over time has a major impact on their dynamics. In particular, depending on the chosen update schedule, the underlying dynamical systems may exhibit more or…

Discrete Mathematics · Computer Science 2022-04-25 Jacques Demongeot , Sylvain Sené

In a graph convolutional network, we assume that the graph $G$ is generated wrt some observation noise. During learning, we make small random perturbations $\Delta{}G$ of the graph and try to improve generalization. Based on quantum…

Machine Learning · Computer Science 2019-07-02 Ke Sun , Piotr Koniusz , Zhen Wang

Message passing neural networks have shown a lot of success on graph-structured data. However, there are many instances where message passing can lead to over-smoothing or fail when neighboring nodes belong to different classes. In this…

The regulation of the cell state is a complex process involving several components. These complex dynamics can be modeled using Boolean networks, allowing us to explain the existence of different cell states and the transition between them.…

Molecular Networks · Quantitative Biology 2010-01-28 Elke K. Markert , Nils Baas , Arnold J. Levine , Alexei Vazquez

Network embeddings learn to represent nodes as low-dimensional vectors to preserve the proximity between nodes and communities of the network for network analysis. The temporal edges (e.g., relationships, contacts, and emails) in dynamic…

Social and Information Networks · Computer Science 2019-06-25 Chuanchang Chen , Yubo Tao , Hai Lin

An embedding is a mapping from a set of nodes of a network into a real vector space. Embeddings can have various aims like capturing the underlying graph topology and structure, node-to-node relationship, or other relevant information about…

Machine Learning · Computer Science 2023-06-21 Ashkan Dehghan , Kinga Siuta , Agata Skorupka , Andrei Betlen , David Miller , Bogumil Kaminski , Pawel Pralat
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