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Sequencing-based studies are emerging as a major tool for genetic association studies of complex diseases. These studies pose great challenges to the traditional statistical methods (e.g., single-locus analyses based on regression methods)…

Methodology · Statistics 2025-08-18 Changshuai Wei , Qing Lu

This paper is about conceptual modeling of aggregates in software engineering. An aggregate is a cluster of domain objects that can be treated as a single unit. In UML, an aggregation is a type of association in which objects are configured…

Software Engineering · Computer Science 2022-08-25 Sabah Al-Fedaghi

Self-supervised learning (SSL) methods via joint embedding architectures have proven remarkably effective at capturing semantically rich representations with strong clustering properties, magically in the absence of label supervision.…

Machine Learning · Computer Science 2025-05-13 Xi Weng , Jianing An , Xudong Ma , Binhang Qi , Jie Luo , Xi Yang , Jin Song Dong , Lei Huang

Consider two independent random strings having same length and taking values uniformly in a common finite alphabet. We study the order of the variance of the length of the longest common subsequences (LCS) of these strings when long blocks,…

Probability · Mathematics 2016-09-26 S. Amsalu , C. Houdré , H. Matzinger

The generalized gluing and resmoothing theorem originally proved by LeClair, Peskin and Preitschopf, gives a powerful formula for the fused vertex obtained by contracting any two vertices in string field theories. Although the theorem is…

High Energy Physics - Theory · Physics 2009-10-31 Tsuguhiko Asakawa , Taichiro Kugo , Tomohiko Takahashi

DNA has immense potential as an emerging data storage medium. The principle of DNA storage is the conversion and flow of digital information between binary code stream, quaternary base, and actual DNA fragments. This process will inevitably…

Information Retrieval · Computer Science 2022-10-21 Yun Qin , Fei Zhu , Bo Xi

Recently, unsupervised parsing of syntactic trees has gained considerable attention. A prototypical approach to such unsupervised parsing employs reinforcement learning and auto-encoders. However, no mechanism ensures that the learnt model…

Computation and Language · Computer Science 2021-05-24 Atul Sahay , Anshul Nasery , Ayush Maheshwari , Ganesh Ramakrishnan , Rishabh Iyer

The human brain, among its several functions, analyzes the double articulation structure in spoken language, i.e., double articulation analysis (DAA). A hierarchical structure in which words are connected to form a sentence and words are…

Neurons and Cognition · Quantitative Biology 2022-07-07 Akira Taniguchi , Maoko Muro , Hiroshi Yamakawa , Tadahiro Taniguchi

This paper presents the first in a series of results that allow us to develop a theory providing finer control over the complexity of normalisation, and in particular of cut elimination. By considering atoms as self-dual non-commutative…

Logic in Computer Science · Computer Science 2022-07-01 Andrea Aler Tubella , Alessio Guglielmi

When we think of model ensembling or ensemble modeling, there are many possibilities that come to mind in different disciplines. For example, one might think of a set of descriptions of a phenomenon in the world, perhaps a time series or a…

For the Research Topic Data Assimilation and Control: Theory and Applications in Life Sciences we first review the formulation of statistical data assimilation (SDA) and discuss algorithms for exploring variational approximations to the…

Neurons and Cognition · Quantitative Biology 2018-09-17 Anna Miller , Dawei Li , Jason Platt , Arij Daou , Daniel Margoliash , Henry Abarbanel

A general prediction of string unification is the existence of exotic states with fractional charges under the free unbroken Abelian generators of the underlying GUT symmetry. Such states may be long-lived due to the existence of weakly…

High Energy Physics - Phenomenology · Physics 2007-05-23 Claudio Coriano , Alon E. Faraggi

Symmetric monoidal theories (SMTs) generalise algebraic theories in a way that make them suitable to express resource-sensitive systems, in which variables cannot be copied or discarded at will. In SMTs, traditional tree-like terms are…

Logic in Computer Science · Computer Science 2022-09-16 Filippo Bonchi , Fabio Gadducci , Aleks Kissinger , Pawel Sobocinski , Fabio Zanasi

The discovery of novel materials and functional molecules can help to solve some of society's most urgent challenges, ranging from efficient energy harvesting and storage to uncovering novel pharmaceutical drug candidates. Traditionally…

Machine Learning · Computer Science 2020-11-06 Mario Krenn , Florian Häse , AkshatKumar Nigam , Pascal Friederich , Alán Aspuru-Guzik

We address the component-based regularisation of a multivariate Generalized Linear Mixed Model (GLMM). A set of random responses Y is modelled by a GLMM, using a set X of explanatory variables, a set T of additional covariates, and random…

Methodology · Statistics 2019-08-22 Jocelyn Chauvet , Catherine Trottier , Xavier Bry , Frederic Mortier

DNA rearrangement processes recombine gene segments that are organized on the chromosome in a variety of ways. The segments can overlap, interleave or one may be a subsegment of another. We use directed graphs to represent segment…

Machine Learning · Statistics 2018-01-30 Mustafa Hajij , Nataša Jonoska , Denys Kukushkin , Masahico Saito

A series of simulations aimed at elucidating the self-assembly dynamics of spherical virus capsids is described. This little-understood phenomenon is a fascinating example of the complex processes that occur in the simplest of organisms.…

Soft Condensed Matter · Physics 2015-05-19 D. C. Rapaport

Graph Neural Networks (GNNs) are a new and increasingly popular family of deep neural network architectures to perform learning on graphs. Training them efficiently is challenging due to the irregular nature of graph data. The problem…

Machine Learning · Computer Science 2021-06-15 Marco Serafini , Hui Guan

We argue that the behavior of string theory at high temperature and high longitudinal boosts, combined with the emergence of p-branes as necessary ingredients in various string dualities, point to a possible reformulation of strings, as…

High Energy Physics - Theory · Physics 2007-05-23 Oren Bergman

Many language generation models are now available for a wide range of generation tasks, including machine translation and summarization. Combining such diverse models may lead to further progress, but ensembling generation models is…

Computation and Language · Computer Science 2022-10-31 Jungo Kasai , Keisuke Sakaguchi , Ronan Le Bras , Hao Peng , Ximing Lu , Dragomir Radev , Yejin Choi , Noah A. Smith
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