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Neural quantum states (NQS) are a novel class of variational many-body wave functions that are very flexible in approximating diverse quantum states. Optimization of an NQS ansatz requires sampling from the corresponding probability…

Strongly Correlated Electrons · Physics 2021-09-15 Andrey A. Bagrov , Askar A. Iliasov , Tom Westerhout

We propose Monte Carlo Permutation Search (MCPS), a general-purpose Monte Carlo Tree Search (MCTS) algorithm that improves upon the GRAVE algorithm. MCPS is relevant when deep reinforcement learning is not an option or when the computing…

Machine Learning · Computer Science 2026-05-27 Tristan Cazenave

We present a geometrically enhanced Markov chain Monte Carlo sampler for networks based on a discrete curvature measure defined on graphs. Specifically, we incorporate the concept of graph Forman curvature into sampling procedures on both…

Machine Learning · Statistics 2021-10-12 John Sigbeku , Emil Saucan , Anthea Monod

Fragment-based shape signature techniques have proven to be powerful tools for computer-aided drug design. They allow scientists to search for target molecules with some similarity to a known active compound. They do not require reference…

Artificial Intelligence · Computer Science 2022-01-05 Thierry Petit , Randy J. Zauhar

Location retrieval based on visual information is to retrieve the location of an agent (e.g. human, robot) or the area they see by comparing the observations with a certain form of representation of the environment. Existing methods…

Computer Vision and Pattern Recognition · Computer Science 2022-08-02 Lijun Wei , Valerie Gouet-Brunet , Anthony Cohn

The field of machine learning for drug discovery is witnessing an explosion of novel methods. These methods are often benchmarked on simple physicochemical properties such as solubility or general druglikeness, which can be readily…

This paper introduces the parallel hierarchical sampler (PHS), a Markov chain Monte Carlo algorithm using several chains simultaneously. The connections between PHS and the parallel tempering (PT) algorithm are illustrated, convergence of…

Computation · Statistics 2008-12-09 Fabio Rigat

This review treats the mathematical and algorithmic foundations of non-reversible Markov chains in the context of event-chain Monte Carlo (ECMC), a continuous-time lifted Markov chain that employs the factorized Metropolis algorithm. It…

Soft Condensed Matter · Physics 2022-08-31 Werner Krauth

The identification of transcription factor binding sites (TFBSs) on genomic DNA is of crucial importance for understanding and predicting regulatory elements in gene networks. TFBS motifs are commonly described by Position Weight Matrices…

Genomics · Quantitative Biology 2015-04-28 Marc Santolini , Thierry Mora , Vincent Hakim

An Automated Sliced Gibbs framework is proposed for fully automated Markov chain Monte Carlo sampling from arbitrary finite dimensional probability kernels. The method targets unnormalized, non-smooth, heavy tailed, and highly multimodal…

Methodology · Statistics 2026-04-01 Prithwish Ghosh , Sujit K Ghosh

Quantum Process Tomography (QPT) is a powerful tool to characterize quantum operations, but it requires considerable resources making it impractical for more than 2-qubit systems. This work proposes an alternative approach that requires…

Quantum Physics · Physics 2022-05-18 Vicente Leyton-Ortega , Tyler Kharazi , Raphael C. Pooser

Monte Carlo and Quasi-Monte Carlo methods present a convenient approach for approximating the expected value of a random variable. Algorithms exist to adaptively sample the random variable until a user defined absolute error tolerance is…

Numerical Analysis · Mathematics 2023-11-14 Aleksei G. Sorokin , Jagadeeswaran Rathinavel

Statistical signal processing applications usually require the estimation of some parameters of interest given a set of observed data. These estimates are typically obtained either by solving a multi-variate optimization problem, as in the…

Computation · Statistics 2021-07-27 D. Luengo , L. Martino , M. Bugallo , V. Elvira , S. Särkkä

We consider the problem of improving kernel approximation via randomized feature maps. These maps arise as Monte Carlo approximation to integral representations of kernel functions and scale up kernel methods for larger datasets. Based on…

Machine Learning · Computer Science 2018-10-31 Marina Munkhoeva , Yermek Kapushev , Evgeny Burnaev , Ivan Oseledets

Quantum process tomography (QPT), where a quantum channel is reconstructed through the analysis of repeated quantum measurements, is an important tool for validating the operation of a quantum processor. We detail the combined use of an…

Quantum Physics · Physics 2021-12-14 Aidan Dang , Gregory A. L. White , Lloyd C. L. Hollenberg , Charles D. Hill

Demonstrating quantum advantage using conventional quantum algorithms remains challenging on current noisy gate-based quantum computers. Automated quantum circuit synthesis via quantum machine learning has emerged as a promising solution,…

Quantum Physics · Physics 2025-04-14 Shubing Xie , Aritra Sarkar , Sebastian Feld

A new method for sequence optimization in protein models is presented. The approach, which has inherited its basic philosophy from recent work by Deutsch and Kurosky [Phys. Rev. Lett. 76, 323 (1996)] by maximizing conditional probabilities…

Soft Condensed Matter · Physics 2009-10-30 Anders Irbäck , Carsten Peterson , Frank Potthast , Erik Sandelin

Factor models balance flexibility, identifiability, and computational efficiency, with Bayesian spatial factor models particularly prone to identifiability challenges and scaling limitations. This work introduces Projected Bayesian Spatial…

Methodology · Statistics 2025-12-16 Lu Zhang

Background: Exonic splice enhancers are sequences embedded within exons which promote and regulate the splicing of the transcript in which they are located. A class of exonic splice enhancers are the SR proteins, which are thought to…

Genomics · Quantitative Biology 2007-05-23 Thomas A. Down , Bernard Leong , Tim J. P. Hubbard

Link prediction plays an important role in network analysis and applications. Recently, approaches for link prediction have evolved from traditional similarity-based algorithms into embedding-based algorithms. However, most existing…

Social and Information Networks · Computer Science 2020-08-11 Lei Wang , Jing Ren , Bo Xu , Jianxin Li , Wei Luo , Feng Xia