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We measure different contributions to entropy production in a living functional epithelial tissue. We do this by extracting the functional dynamics of development while at the same time quantifying fluctuations. Using the translucent…

Soft Condensed Matter · Physics 2023-01-25 Mark Olenik , Jake Turley , Stephen Cross , Helen Weavers , Paul Martin , Isaac Chenchiah , Tanniemola Liverpool

One of the key characteristics of cancer cells is an increased phenotypic plasticity, driven by underlying genetic and epigenetic perturbations. However, at a systems-level it is unclear how these perturbations give rise to the observed…

Molecular Networks · Quantitative Biology 2015-04-30 Andrew E. Teschendorff , Christopher R. S. Banerji , Simone Severini , Reimer Kuehn , Peter Sollich

Entropy production during the process of thermal phase-separation of multiphase flows is investigated by means of a discrete Boltzmann kinetic model. The entropy production rate is found to increase during the spinodal decomposition stage…

Statistical Mechanics · Physics 2019-03-18 Yudong Zhang , Aiguo Xu , Guangcai Zhang , Yanbiao Gan , Zhihua Chen , Sauro Succi

The expressions for entropy production, free energy, and entropy extraction rates are derived for a Brownian particle that walks in an underdamped medium. Our analysis indicates that as long as the system is driven out of equilibrium, it…

Statistical Mechanics · Physics 2021-02-18 Mesfin Asfaw Taye

The purpose of this study was to investigate how the entropy of a neuron cell can be measured using membrane ion current signals, which were recorded from neurons in the mouse medial prefrontal cortex (mPFC). The sample entropy and the…

Neurons and Cognition · Quantitative Biology 2025-08-05 Mahmut Akilli

Entropy production is often interpreted as a proxy for microscopic disorder or environmental roughness in stochastic systems. We test this interpretation using controlled simulations of overdamped stochastic dynamics on curved surfaces in…

Statistical Mechanics · Physics 2026-02-23 Patrick Romanescu

The topology of gene expression space for a set of 12 cancer types is studied by means of an entropy-like magnitude, which allows the characterization of the regions occupied by tumor and normal samples. The comparison indicates that the…

Tissues and Organs · Quantitative Biology 2022-05-19 Augusto Gonzalez , Frank Quintela , Dario A. Leon , Maria Luisa Bringas Vega , Pedro Valdes Sosa

The stochastic entropy generated during the evolution of a system interacting with an environment may be separated into three components, but only two of these have a non-negative mean. The third component of entropy production is…

Statistical Mechanics · Physics 2013-05-30 Ian J. Ford , Richard E. Spinney

Frequency up-conversion of few low-energy photons into a single high-energy photon, greatly contributes to imaging, light sources, detection and other fields of research. However, it offers negligible efficiency when up-converting many…

Optics · Physics 2013-06-11 Assaf Manor , Nimrod Kruger , Carmel Rotschild

There is ongoing interest in the global entropy production rate as a climate diagnostic and predictor, but progress has been limited by ambiguities in its definition; different conceptual boundaries of the climate system give rise to…

Atmospheric and Oceanic Physics · Physics 2020-10-28 Goodwin Gibbins , Joanna D. Haigh

The hotness of the sun and the coldness of the outer space are inexhaustible thermodynamic resources for human beings. From a thermodynamic point of view, any energy conversion systems that receive energy from the sun and/or dissipate…

Applied Physics · Physics 2018-05-08 Bolin Liao

The tendency of irreversible processes to generate entropy is the ultimate driving force for the evolution of nature. In engineering, entropy production is often used as a measure of usable energy losses. In this study we show that the…

Geophysics · Physics 2018-10-30 Yi Yang , Stefan Bruns , Susan Stipp , Henning Sørensen

Nonequilibrium processes break time-reversal symmetry and generate entropy. Living systems are driven out-of-equilibrium at the microscopic level of molecular motors that exploit chemical potential gradients to transduce free energy to…

Statistical Mechanics · Physics 2022-12-06 Eden Nitzan , Aishani Ghosal , Gili Bisker

Fluctuating entropy production is studied for a set of linearly coupled complex fields. The general result is applied to non-equilibrium fluctuating hydrodynamic equations for coarse-grained fields (density, temperature and velocity), in…

Statistical Mechanics · Physics 2012-07-09 Giacomo Gradenigo , Andrea Puglisi , Alessandro Sarracino

We investigate how entanglement entropy can drive particle creation, deriving explicit relations between entropy and the radiated particle spectrum, the total number of particles, and the total energy. Particle production is computed for…

Quantum Physics · Physics 2026-02-04 Michael R. R. Good , Evgenii Ievlev , Eric V. Linder

The out-of-equilibrium character of active systems is often twofold, arising from both the activity itself and from non-reciprocal couplings between constituents. A well-established measure to quantify the system's distance from equilibrium…

Statistical Mechanics · Physics 2026-02-13 Kim L. Kreienkamp , Sabine H. L. Klapp

Entropy production along a single stochastic trajectory of a biomolecule is discussed for two different sources of non-equilibrium. For a molecule manipulated mechanically by an AFM or an optical tweezer, entropy production (or…

Statistical Mechanics · Physics 2007-06-20 Tim Schmiedl , Thomas Speck , Udo Seifert

Entropy production (EP) is known as a fundamental quantity for measuring the irreversibility of processes in thermal equilibrium and states far from equilibrium. In stochastic thermodynamics, the EP becomes more visible in terms of the…

Statistical Mechanics · Physics 2020-06-24 Jaewoo Jung , Jaegon Um , Deokjae Lee , Yong W. Kim , D. Y. Lee , H. K. Pak , B. Kahng

Entropy generation in a chemical reaction is analyzed without using the general formalism of non-equilibrium thermodynamics at a level adequate for advanced undergraduates. In a first approach to the problem, the phenomenological kinetic…

General Physics · Physics 2015-06-11 E. N. Miranda

We define the entropy operator as the negative of the logarithm of the density matrix, give a prescription for extracting its thermodynamically measurable part, and discuss its dynamics. For an isolated system we derive the first, second…

Statistical Mechanics · Physics 2016-07-06 E. Solano-Carrillo , A. J. Millis