English
Related papers

Related papers: Response of Boolean networks to perturbations

200 papers

Recurrence networks are complex networks, constructed from time series data, having several practical applications. Though their properties when constructed with the threshold value \epsilon chosen at or just above the percolation threshold…

Chaotic Dynamics · Physics 2016-07-19 Rinku Jacob , K. P. Harikrishnan , R. Misra , G. Ambika

Boolean networks, widely used to model gene regulation, exhibit a phase transition between regimes in which small perturbations either die out or grow exponentially. We show and numerically verify that this phase transition in the dynamics…

Statistical Mechanics · Physics 2013-05-30 Shane Squires , Edward Ott , Michelle Girvan

Consider a large Boolean network with a feed forward structure. Given a probability distribution on the inputs, can one find, possibly small, collections of input nodes that determine the states of most other nodes in the network? To answer…

Information Theory · Computer Science 2013-05-23 Reinhard Heckel , Steffen Schober , Martin Bossert

In this work, several random Boolean networks (RBN) are generated and analyzed from two characteristics: their time evolution diagram and their transition diagram. For this purpose, its randomness is estimated using three measures, of which…

Information Theory · Computer Science 2024-09-04 Manuel de J. Luevano , Alejandro Puga

The deterministic dynamics of randomly connected neural networks are studied, where a state of binary neurons evolves according to a discreet-time synchronous update rule. We give a theoretical support that the overlap of systems' states…

Statistical Mechanics · Physics 2015-03-10 Taro Toyoizumi , Haiping Huang

In this work we consider random Boolean networks that provide a general model for genetic regulatory networks. We extend the analysis of James Lynch who was able to proof Kauffman's conjecture that in the ordered phase of random networks,…

Cellular Automata and Lattice Gases · Physics 2007-05-23 Steffen Schober , Martin Bossert

Boolean networks, inspired by gene regulatory networks, were developed to understand the complex behaviors observed in biological systems, with network attractors corresponding to biological phenotypes or cell types. In this article, we…

Molecular Networks · Quantitative Biology 2025-11-25 Venkata Sai Narayana Bavisetty , Matthew Wheeler , Reinhard Laubenbacher , Claus Kadelka

To model biological systems using networks, it is desirable to allow more than two levels of expression for the nodes and to allow the introduction of parameters. Various modeling and simulation methods addressing these needs using Boolean…

Molecular Networks · Quantitative Biology 2014-04-23 Yi Ming Zou

Boolean networks have been used in a variety of settings, as models for general complex systems as well as models of specific systems in diverse fields, such as biology, engineering, and computer science. Traditionally, their properties as…

Dynamical Systems · Mathematics 2024-02-02 Matthew Wheeler , Claus Kadelka , Alan Veliz-Cuba , David Murrugarra , Reinhard Laubenbacher

Random Boolean networks have been used widely to explore aspects of gene regulatory networks. A modified form of the model through which to systematically explore the effects of increasing the number of gene states has previously been…

Molecular Networks · Quantitative Biology 2023-02-06 Larry Bull

The evaluation of the number of attractors in Kauffman networks by Samuelsson and Troein is generalized to critical networks with one input per node and to networks with two inputs per node and different probability distributions for update…

Statistical Mechanics · Physics 2009-11-11 Barbara Drossel

Interacting biological systems at all organizational levels display emergent behavior. Modeling these systems is made challenging by the number and variety of biological components and interactions (from molecules in gene regulatory…

Molecular Networks · Quantitative Biology 2023-10-20 Jordan C. Rozum , Colin Campbell , Eli Newby , Fatemeh Sadat Fatemi Nasrollahi , Reka Albert

Despite the large quantity of information available, thorough researches in various biological databases are still needed in order to reconstruct and understand the steps that lead to known or new phenomena. By using protein-protein…

Molecular Networks · Quantitative Biology 2014-12-03 Alberto Calderone

The study of the response of complex dynamical social, biological, or technological networks to external perturbations has numerous applications. Random Boolean Networks (RBNs) are commonly used a simple generic model for certain dynamics…

Disordered Systems and Neural Networks · Physics 2009-04-29 Qiming Lu , Christof Teuscher

Networks of coupled phase oscillators are one of the most studied dynamical systems with numerous applications in physics, chemistry, biology, and engineering. Their behaviour is often characterized by the emergence of various partially…

Pattern Formation and Solitons · Physics 2026-02-27 Oleh E. Omel'chenko

The problem of reliability of the dynamics in biological regulatory networks is studied in the framework of a generalized Boolean network model with continuous timing and noise. Using well-known artificial genetic networks such as the…

Molecular Networks · Quantitative Biology 2008-05-28 Stefan Braunewell , Stefan Bornholdt

Complex systems are often modeled as Boolean networks in attempts to capture their logical structure and reveal its dynamical consequences. Approximating the dynamics of continuous variables by discrete values and Boolean logic gates may,…

Molecular Networks · Quantitative Biology 2013-05-29 Johannes Norrell , Joshua E. S. Socolar

Boolean networks with canalizing functions are used to model gene regulatory networks. In order to learn how such networks may behave under evolutionary forces, we simulate the evolution of a single Boolean network by means of an adaptive…

Populations and Evolution · Quantitative Biology 2011-11-09 Agnes Szejka , Barbara Drossel

We present a rigorous mathematical framework for analyzing dynamics of a broad class of Boolean network models. We use this framework to provide the first formal proof of many of the standard critical transition results in Boolean network…

Disordered Systems and Neural Networks · Physics 2016-08-30 C. Seshadhri , Yevgeniy Vorobeychik , Jackson R. Mayo , Robert C. Armstrong , Joseph R. Ruthruff

We derive an exact representation of the topological effect on the dynamics of sequence processing neural networks within signal-to-noise analysis. A new network structure parameter, loopiness coefficient, is introduced to quantitatively…

Disordered Systems and Neural Networks · Physics 2008-05-11 Pan Zhang , Yong Chen