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Suppose an agent is in a (possibly unknown) Markov Decision Process in the absence of a reward signal, what might we hope that an agent can efficiently learn to do? This work studies a broad class of objectives that are defined solely as…

Machine Learning · Computer Science 2019-01-29 Elad Hazan , Sham M. Kakade , Karan Singh , Abby Van Soest

Many problems are NP-hard and, unless P = NP, do not admit polynomial-time exact algorithms. The fastest known exact algorithms exactly usually take time exponential in the input size. Much research effort has gone into obtaining faster…

Data Structures and Algorithms · Computer Science 2025-01-27 Stefan Kratsch , Pascal Kunz

Background: It is of biological interest to make genome-wide predictions of the locations of DNA melting bubbles using statistical mechanics models. Computationally, this poses the challenge that a generic search through all combinations of…

Biomolecules · Quantitative Biology 2008-07-19 Eivind Tøstesen

A time series motif intuitively is a short time series that repeats itself approximately the same within a larger time series. Such motifs often represent concealed structures, such as heart beats in an ECG recording, the riff in a pop…

Machine Learning · Computer Science 2024-04-18 Patrick Schäfer , Ulf Leser

We analyze the convergence rate of a simplified version of a popular Gibbs sampling method used for statistical discovery of gene regulatory binding motifs in DNA sequences. This sampler satisfies a very strong form of ergodicity (uniform).…

Statistics Theory · Mathematics 2013-03-13 Dawn B. Woodard , Jeffrey S. Rosenthal

We describe a new, surprisingly simple algorithm, that simulates exact sample paths of a class of stochastic differential equations. It involves rejection sampling and, when applicable, returns the location of the path at a random…

Probability · Mathematics 2007-05-23 Alexandros Beskos , Gareth O. Roberts

Markov automata combine non-determinism, probabilistic branching, and exponentially distributed delays. This compositional variant of continuous-time Markov decision processes is used in reliability engineering, performance evaluation and…

Logic in Computer Science · Computer Science 2017-05-11 Tim Quatmann , Sebastian Junges , Joost-Pieter Katoen

We study the D-optimal Data Fusion (DDF) problem, which aims to select new data points, given an existing Fisher information matrix, so as to maximize the logarithm of the determinant of the overall Fisher information matrix. We show that…

Optimization and Control · Mathematics 2022-08-09 Yongchun Li , Marcia Fampa , Jon Lee , Feng Qiu , Weijun Xie , Rui Yao

Approximate Bayesian Computation has been successfully used in population genetics to bypass the calculation of the likelihood. These methods provide accurate estimates of the posterior distribution by comparing the observed dataset to a…

The efficiency of reservoir simulation is important for automated history matching (AHM) and production optimization, etc. The fast marching marching method (FMM) has been used for efficient reservoir simulation. FMM can be regarded as a…

Fluid Dynamics · Physics 2021-09-28 Zhao Zhang , Jianchun Guo , Kai Zhang , Piyang Liu , Xia Yan

Every organism in an environment, whether biological, robotic or virtual, must be able to predict certain aspects of its environment in order to survive or perform whatever task is intended. It needs a model that is capable of estimating…

Machine Learning · Computer Science 2013-11-12 Stefan Richthofer , Laurenz Wiskott

Determinantal point processes (DPPs) are popular probabilistic models that arise in many machine learning tasks, where distributions of diverse sets are characterized by matrix determinants. In this paper, we develop fast algorithms to find…

Discrete Mathematics · Computer Science 2017-06-15 Insu Han , Prabhanjan Kambadur , Kyoungsoo Park , Jinwoo Shin

Matrix completion is the problem of recovering a low rank matrix by observing a small fraction of its entries. A series of recent works [KOM12,JNS13,HW14] have proposed fast non-convex optimization based iterative algorithms to solve this…

Numerical Analysis · Computer Science 2014-11-06 Prateek Jain , Praneeth Netrapalli

Motivation: Many inference tools use the Perfect Phylogeny Model (PPM) to learn trees from noisy variant allele frequency (VAF) data. Learning in this setting is hard, and existing tools use approximate or heuristic algorithms. An…

Quantitative Methods · Quantitative Biology 2019-08-26 Surjyendu Ray , Bei Jia , Sam Safavi , Tim van Opijnen , Ralph Isberg , Jason Rosch , José Bento

Doubly intractable distributions arise in many settings, for example in Markov models for point processes and exponential random graph models for networks. Bayesian inference for these models is challenging because they involve intractable…

Computation · Statistics 2019-04-03 Jaewoo Park , Murali Haran

Approximate inference in high-dimensional, discrete probabilistic models is a central problem in computational statistics and machine learning. This paper describes discrete particle variational inference (DPVI), a new approach that…

Machine Learning · Statistics 2015-12-08 Ardavan Saeedi , Tejas D Kulkarni , Vikash Mansinghka , Samuel Gershman

Large-scale Markov decision processes (MDPs) require planning algorithms with runtime independent of the number of states of the MDP. We consider the planning problem in MDPs using linear value function approximation with only weak…

Machine Learning · Computer Science 2020-07-14 Roshan Shariff , Csaba Szepesvári

The identification and counting of small graph patterns, called network motifs, is a fundamental primitive in the analysis of networks, with application in various domains, from social networks to neuroscience. Several techniques have been…

Social and Information Networks · Computer Science 2021-01-19 Ilie Sarpe , Fabio Vandin

Many chemical reactions and molecular processes occur on timescales that are significantly longer than those accessible by direct simulation. One successful approach to estimating dynamical statistics for such processes is to use many short…

Computational Physics · Physics 2024-10-03 Chatipat Lorpaiboon , Spencer C. Guo , John Strahan , Jonathan Weare , Aaron R. Dinner

Numerical simulation of continuous-time Markovian processes is an essential and widely applied tool in the investigation of epidemic spreading on complex networks. Due to the high heterogeneity of the connectivity structure through which…

Physics and Society · Physics 2017-07-26 Wesley Cota , Silvio C. Ferreira