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The visual information in V1 is processed by an array of modules called orientation preference columns. In some species including humans, orientation columns are radially arranged around singular points like the spokes of a wheel, that are…

Mathematical Physics · Physics 2010-07-09 Davide Barbieri , Giovanna Citti , Gonzalo Sanguinetti , Alessandro Sarti

Neurons in the visual cortex respond best to rod-like stimuli of given orientation. While the preferred orientation varies continuously across most of the cortex, there are prominent pinwheel centers around which all orientations a re…

Statistical Mechanics · Physics 2009-11-10 Ha Youn Lee , Mehdi Yahyanejad , Mehran Kardar

Large-scale functional networks have been extensively studied using resting state functional magnetic resonance imaging. However, the pattern, organization, and function of fine-scale network activity remain largely unknown. Here we…

Neurons and Cognition · Quantitative Biology 2017-03-01 Kun-Han Lu , Jun Young Jeong , Haiguang Wen , Zhongming Liu

The synaptic connectivity of cortical networks features an overrepresentation of certain wiring motifs compared to simple random-network models. This structure is shaped, in part, by synaptic plasticity that promotes or suppresses…

Neurons and Cognition · Quantitative Biology 2014-12-23 Gabriel Koch Ocker , Ashok Litwin-Kumar , Brent Doiron

The pattern formation in orientation and ocular dominance columns is one of the most investigated problems in the brain. From a known cortical structure, we build spin-like Hamiltonian models with long-range interactions of the Mexican hat…

Biological Physics · Physics 2009-11-10 Myoung Won Cho , Seunghwan Kim

Neural systems face the challenge of maintaining reliable representations amid variations from plasticity and spontaneous activity. In particular, the spontaneous dynamics in neuronal circuit is known to operate near a highly variable…

Neurons and Cognition · Quantitative Biology 2026-03-24 Zhuda Yang , Junhao Liang , Wing Ho Yung , Changsong Zhou

Living neural networks in our brains autonomously self-organize into large, complex architectures during early development to result in an organized and functional organic computational device. A key mechanism that enables the formation of…

Neural and Evolutionary Computing · Computer Science 2020-06-15 Guruprasad Raghavan , Cong Lin , Matt Thomson

Self-organized criticality has been proposed to be a universal mechanism for the emergence of scale-free dynamics in many complex systems, and possibly in the brain. While such scale-free patterns were identified experimentally in many…

Neurons and Cognition · Quantitative Biology 2021-05-11 Roxana Zeraati , Viola Priesemann , Anna Levina

One fascinating aspect of the brain is its ability to process information in a fast and reliable manner. The functional architecture is thought to play a central role in this task, by encoding efficiently complex stimuli and facilitating…

Neurons and Cognition · Quantitative Biology 2016-02-17 Alberto Romagnoni , Jérôme Ribot , Daniel Bennequin , Jonathan D. Touboul

Cognition is supported by neurophysiological processes that occur both in local anatomical neighborhoods and in distributed large-scale circuits. Recent evidence from network control theory suggests that white matter pathways linking…

Neurons and Cognition · Quantitative Biology 2016-06-30 John D. Medaglia , Shi Gu , Fabio Pasqualetti , Rebecca L. Ashare , Caryn Lerman , Joseph Kable , Danielle S. Bassett

The enormous diversity of life forms thriving in drastically different environmental milieus involves a complex interplay among constituent proteins interacting with each other. However, the organizational principles characterizing the…

Molecular Networks · Quantitative Biology 2024-01-30 Vikram Singh , Vikram Singh

We investigate a discrete model consisting of self-propelled particles that obey simple interaction rules. We show that this model can self-organize and exhibit coherent localized solutions in one- and in two-dimensions.In one-dimension,…

Soft Condensed Matter · Physics 2009-10-31 Herbert Levine , Wouter-Jan Rappel , Inon Cohen

Many cortical areas increase in size considerably during postnatal development, progressively displacing neuronal cell bodies from each other. At present, little is known about how cortical growth affects the development of neuronal…

Neurons and Cognition · Quantitative Biology 2011-04-12 Wolfgang Keil , Karl-Friedrich Schmidt , Siegrid Loewel , Matthias Kaschube

Brain organoids recapitulate a number of brain properties, including neuronal diversity. However, do they recapitulate brain structure? Using a hydrodynamic description for cell nuclei as particles interacting initially via an effective,…

Soft Condensed Matter · Physics 2021-12-15 Ahmad Borzou , J. M. Schwarz

We present an analytical approach for studying the coupled development of ocular dominance and orientation preference columns. Using this approach we demonstrate that ocular dominance segregation can induce the stabilization and even the…

Neurons and Cognition · Quantitative Biology 2013-05-29 Lars Reichl , Siegrid Löwel , Fred Wolf

Grid cells in the entorhinal cortex are believed to establish their regular, spatially correlated firing patterns by path integration of the animal's motion. Mechanisms for path integration, e.g. in attractor network models, predict…

Neurons and Cognition · Quantitative Biology 2018-08-07 Eli Pollock , Niral Desai , Xue-Xin Wei , Vijay Balasubramanian

It is an attractive hypothesis that the spatial structure of visual cortical architecture can be explained by the coordinated optimization of multiple visual cortical maps representing orientation preference (OP), ocular dominance (OD),…

Neurons and Cognition · Quantitative Biology 2015-06-03 Lars Reichl , Dominik Heide , Siegrid Löwel , Justin C. Crowley , Matthias Kaschube , Fred Wolf

The principle of self-organization has acquired a fundamental significance in the newly emerging field of computational philosophy. Self-organizing systems have been described in various domains in science and philosophy including physics,…

Neurons and Cognition · Quantitative Biology 2020-11-12 Birgitta Dresp-Langley

Large networks of spiking neurons show abrupt changes in their collective dynamics resembling phase transitions studied in statistical physics. An example of this phenomenon is the transition from irregular, noise-driven dynamics to…

Adaptation and Self-Organizing Systems · Physics 2008-11-25 Vicenç Gómez , Andreas Kaltenbrunner , Vicente López , Hilbert J. Kappen

Spontaneously evolving living systems can be modelled as continuous-time dynamical systems (DSs), whose evolution rules are determined by their velocity vector fields. We point out that because of their architectural plasticity, biological…

Adaptation and Self-Organizing Systems · Physics 2016-02-09 Natalia B. Janson , Christopher J. Marsden
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