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The evolution of a continuous time Markov process with a finite number of states is usually calculated by the Master equation - a linear differential equations with a singular generator matrix. We derive a general method for reducing the…

Quantitative Methods · Quantitative Biology 2012-07-19 Daniel Soudry , Ron Meir

Many biological systems can be described by finite Markov models. A general method for simplifying master equations is presented that is based on merging adjacent states. The approach preserves the steady-state probability distribution and…

Biological Physics · Physics 2021-03-01 David Seiferth , Peter Sollich , Stefan Klumpp

Models invoking the chemical master equation are used in many areas of science, and, hence, their simulation is of interest to many researchers. The complexity of the problems at hand often requires considerable computational power, so a…

Biological Physics · Physics 2016-03-02 Fabian Spill , Philip K. Maini , Helen Byrne

Here we develop an effective approach to simplify two-time-scale Markov chains with infinite state spaces by removal of states with fast leaving rates, which improves the simplification method of finite Markov chains. We introduce the…

Molecular Networks · Quantitative Biology 2017-09-13 Chen Jia

We present a simple analytical method to solve master equations for finite temperatures and any initial conditions, which consists in the expansion of the density operator into normal modes. These modes and the expansion coefficients are…

Quantum Physics · Physics 2007-05-23 R. Rangel , L. Carvalho

State-space smoothing has found many applications in science and engineering. Under linear and Gaussian assumptions, smoothed estimates can be obtained using efficient recursions, for example Rauch-Tung-Striebel and Mayne-Fraser algorithms.…

Optimization and Control · Mathematics 2016-09-27 A. Y. Aravkin , J. V. Burke , L. Ljung , A. Lozano , G. Pillonetto

In this paper, we build on recent work using a mathematical programming approach for incremental state update in analysis of non-linear mechanics models. In particular, we consider quasi-static analysis of continuum problems in the…

Optimization and Control · Mathematics 2015-06-23 Zahrasadat Lotfian , Mettupalayam Sivaselvan

We study, from a purely quantitative point of view, the quasi-steady-state assumption for the fundamental mathematical model of the general enzymatic reaction: we re-establish, on a rigorous basis, certain already known results and we…

Dynamical Systems · Mathematics 2021-10-01 Vasiliki Bitsouni , Nikolaos Gialelis , Ioannis G. Stratis

Methods for the reduction of the complexity of computational problems are presented, as well as their connections to renormalization, scaling, and irreversible statistical mechanics. Several statistically stationary cases are analyzed; for…

Numerical Analysis · Mathematics 2007-05-23 Alexandre J. Chorin , Panagiotis Stinis

We study classical stochastic systems with discrete states, coupled to switching external environments. For fast environmental processes we derive reduced dynamics for the system itself, focusing on corrections to the adiabatic limit of…

Statistical Mechanics · Physics 2019-03-27 Peter G. Hufton , Yen Ting Lin , Tobias Galla

We propose a novel method for fast and scalable evaluation of periodic solutions of systems of ordinary differential equations for a given set of parameter values and initial conditions. The equations governing the system dynamics are…

Dynamical Systems · Mathematics 2016-05-30 I. Yu. Tyukin , A. N. Gorban , T. A. Tyukina , J. Al Ameri , Yu. A. Korablev

We derive a simple expression for the probability of trajectories of a master equation. The expression is particularly useful when the number of states is small and permits the calculation of observables that can be defined as functionals…

Statistical Mechanics · Physics 2009-02-23 Andrew D. Jackson , Simone Pigolotti

The Master equation describes the time evolution of the probabilities of a system with a discrete state space. This time evolution approaches for long times a stationary state that will in general depend on the initial probability…

Mathematical Physics · Physics 2022-03-09 Bernd Fernengel , Barbara Drossel

We introduce an alternative way to derive the generalized form of the master equation recently presented by J. P. Pekola et al. [Phys. Rev. Lett. 105, 030401 (2010)] for an adiabatically steered two-level quantum system interacting with a…

Quantum Physics · Physics 2011-12-22 J. Salmilehto , P. Solinas , J. Ankerhold , M. Möttönen

Emerging sampling algorithms based on normalizing flows have the potential to solve ergodicity problems in lattice calculations. Furthermore, it has been noted that flows can be used to compute thermodynamic quantities which are difficult…

High Energy Physics - Lattice · Physics 2023-10-02 Jan M. Pawlowski , Julian M. Urban

We propose a new formulation of stochastic thermodynamics for systems subjected to nonequilibrium constraints (i.e. broken detailed balance at steady state) and furthermore driven by external time-dependent forces. A splitting of the second…

Statistical Mechanics · Physics 2015-05-18 Massimiliano Esposito , Christian Van den Broeck

Some general dynamical properties of models for compaction of granular media based on master equations are analyzed. In particular, a one-dimensional lattice model with short-ranged dynamical constraints is considered. The stationary state…

Statistical Mechanics · Physics 2009-10-31 A. Prados , J. Javier Brey , B. Sanchez-Rey

Although many efficient heuristics have been developed to solve binary optimization problems, these typically produce correlated solutions for degenerate problems. Most notably, transverse-field quantum annealing - the heuristic employed in…

Disordered Systems and Neural Networks · Physics 2019-06-27 Zheng Zhu , Andrew J. Ochoa , Helmut G. Katzgraber

The recent experimental progresses in handling microscopic systems have allowed to probe them at levels where fluctuations are prominent, calling for stochastic modeling in a large number of physical, chemical and biological phenomena. This…

Statistical Mechanics · Physics 2017-03-08 Stefano Bo , Antonio Celani

The totally asymmetric simple exclusion process (TASEP) is a stochastic model for the unidirectional dynamics of interacting particles on a $1$D-lattice that is much used in systems biology and statistical physics. Its master equation…

Statistical Mechanics · Physics 2024-08-01 Kilian Pioch , Thomas Kriecherbauer , Michael Margaliot , Lars Grüne
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