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Deep clustering as an important branch of unsupervised representation learning focuses on embedding semantically similar samples into the identical feature space. This core demand inspires the exploration of contrastive learning and…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Haifeng Xia , Hai Huang , Zhengming Ding

Cancers are characterized by remarkable heterogeneity and diverse prognosis. Accurate cancer classification is essential for patient stratification and clinical decision-making. Although digital pathology has been advancing cancer diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Xiaofei Wang , Hanyu Liu , Yupei Zhang , Boyang Zhao , Hao Duan , Wanming Hu , Yonggao Mou , Stephen Price , Chao Li

Compact Genetic Algorithms (cGAs) are condensed variants of classical Genetic Algorithms (GAs) that use a probability vector representation of the population instead of the complete population. cGAs have been shown to significantly reduce…

Neural and Evolutionary Computing · Computer Science 2025-04-07 Prasanta Dutta , Anirban Mukhopadhyay

Support Vector Machines (SVM), a popular machine learning technique, has been applied to a wide range of domains such as science, finance, and social networks for supervised learning. Whether it is identifying high-risk patients by…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-06-20 Jeyanthi Narasimhan , Abhinav Vishnu , Lawrence Holder , Adolfy Hoisie

In cancer research, profiling studies have been extensively conducted, searching for genes/SNPs associated with prognosis. Cancer is a heterogeneous disease. Examining similarity and difference in the genetic basis of multiple subtypes of…

Methodology · Statistics 2013-04-18 Jin Liu , Jian Huang , Yawei Zhang , Qing Lan , Nathaniel Rothman , Tongzhang Zheng , Shuangge Ma

The support vector machine (SVM) is a supervised learning algorithm that finds a maximum-margin linear classifier, often after mapping the data to a high-dimensional feature space via the kernel trick. Recent work has demonstrated that in…

Machine Learning · Statistics 2026-04-16 Chiraag Kaushik , Andrew D. McRae , Mark A. Davenport , Vidya Muthukumar

Cancer genomes exhibit a large number of different alterations that affect many genes in a diverse manner. It is widely believed that these alterations follow combinatorial patterns that have a strong connection with the underlying…

Machine Learning · Computer Science 2016-01-26 Jack P. Hou , Amin Emad , Gregory J. Puleo , Jian Ma , Olgica Milenkovic

Support vector machine (SVM) is a well-known statistical technique for classification problems in machine learning and other fields. An important question for SVM is the selection of covariates (or features) for the model. Many studies have…

Methodology · Statistics 2022-02-22 Jiahui Zou , Chaoxia Yuan , Xinyu Zhang , Guohua Zou , Alan T. K. Wan

This paper proposes a robust classification model, based on support vector machine (SVM), which simultaneously deals with outliers detection and feature selection. The classifier is built considering the ramp loss margin error and it…

Optimization and Control · Mathematics 2024-03-13 Marta Baldomero-Naranjo , Luisa I. Martínez-Merino , Antonio M. Rodríguez-Chía

Despite advances in feature representation, leveraging geometric relations is crucial for establishing reliable visual correspondences under large variations of images. In this work we introduce a Hough transform perspective on…

Computer Vision and Pattern Recognition · Computer Science 2021-04-01 Juhong Min , Minsu Cho

The revolutionary developments in the field of supervised machine learning have paved way to the development of CAD tools for assisting doctors in diagnosis. Recently, the former has been employed in the prediction of neurological disorders…

Computer Vision and Pattern Recognition · Computer Science 2017-06-27 Jerrin Thomas Panachakel , Jeena R. S.

Due to its powerful capability of self-supervised representation learning and clustering, contrastive attributed graph clustering (CAGC) has achieved great success, which mainly depends on effective data augmentation and contrastive…

Machine Learning · Computer Science 2025-10-06 Tianxiang Zhao , Youqing Wang , Jinlu Wang , Jiapu Wang , Mingliang Cui , Junbin Gao , Jipeng Guo

Background: Identification of causal SNPs in most genome wide association studies relies on approaches that consider each SNP individually. However, there is a strong correlation structure among SNPs that need to be taken into account.…

Applications · Statistics 2012-11-02 Verena Zuber , A. Pedro Duarte Silva , Korbinian Strimmer

Gene expression data sets are used to classify and predict patient diagnostic categories. As we know, it is extremely difficult and expensive to obtain gene expression labelled examples. Moreover, conventional supervised approaches cannot…

Machine Learning · Computer Science 2013-07-05 Hala Helmi , Jon M. Garibaldi , Uwe Aickelin

In this paper, we consider the binary classification problem via distributed Support-Vector-Machines (SVM), where the idea is to train a network of agents, with limited share of data, to cooperatively learn the SVM classifier for the global…

Systems and Control · Electrical Eng. & Systems 2021-04-02 Mohammadreza Doostmohammadian , Alireza Aghasi , Themistoklis Charalambous , Usman A. Khan

Multi-modal hashing methods have gained popularity due to their fast speed and low storage requirements. Among them, the supervised methods demonstrate better performance by utilizing labels as supervisory signals compared with unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2024-12-20 Jin-Yu Liu , Xian-Ling Mao , Tian-Yi Che , Rong-Cheng Tu

Background: Cancers are highly heterogeneous with different subtypes. These subtypes often possess different genetic variants, present different pathological phenotypes, and most importantly, show various clinical outcomes such as varied…

Graphics · Computer Science 2014-07-09 Hao Ding , Chao Wang , Kun Huang , Raghu Machiraju

Cancer subtyping is crucial for understanding the nature of tumors and providing suitable therapy. However, existing labelling methods are medically controversial, and have driven the process of subtyping away from teaching signals.…

Machine Learning · Computer Science 2022-11-15 Zheng Chen , Lingwei Zhu , Ziwei Yang , Takashi Matsubara

In this article we are describing a new algorithm for detecting and validating partial horizontal gene transfers (HGT). The presented algorithm is based on a sliding window procedure which analyzes fragments of the given multiple sequence…

Quantitative Methods · Quantitative Biology 2021-12-28 Boc Alix , Diallo Alpha Boubacar , Makarenkov Vladimir

Spatial variable genes (SVGs) reveal critical information about tissue architecture, cellular interactions, and disease microenvironments. As spatial transcriptomics (ST) technologies proliferate, accurately identifying SVGs across diverse…

Applications · Statistics 2025-10-21 Jiawen Chen , Jinwei Zhang , Dongshen Peng , Yutong Song , Aitong Ruan , Yun Li , Didong Li
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