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Related papers: Fluctuation Induced Homochirality

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We show how spatiotemporal fluctuations can induce spontaneous symmetry breaking in systems which are perfectly symmetric in the absence of fluctuations. We illustrate this in the context of the autocatalytic production of chiral…

Soft Condensed Matter · Physics 2007-05-23 V. S. Gayathri , Madan Rao

The observed single-handedness of biological amino acids and sugars has long been attributed to autocatalysis. However, the stability of homochiral states in deterministic autocatalytic systems relies on cross inhibition of the two chiral…

Populations and Evolution · Quantitative Biology 2015-10-14 Farshid Jafarpour , Tommaso Biancalani , Nigel Goldenfeld

A nonlinear autocatalysis of a chiral substance is shown to achieve homochirality in a closed system, if the back-reaction is included. Asymmetry in the concentration of two enantiomers or the enantiometric excess increases due to the…

Chemical Physics · Physics 2008-11-26 Yukio Saito , Hiroyuki Hyuga

The selection of a single molecular handedness, or homochirality across all living matter, is a mystery in the origin of life. Frank's seminal model showed in the fifties how chiral symmetry breaking can occur in non-equilibrium chemical…

Statistical Mechanics · Physics 2021-01-25 Gabin Laurent , David Lacoste , Pierre Gaspard

To understand the chirality selection in the biological organic system, a simple lattice model of chemical reaction with molecular diffusion is proposed and studied by Monte Carlo simulations. In addition to a simple stochastic process of…

Chemical Physics · Physics 2007-07-20 Yukio Saito , Hiroyuki Hyuga

Biochemical processes typically involve many chemical species, some in abundance and some in low molecule numbers. Here we first identify the rate constant limits under which the concentrations of a given set of species will tend to…

Quantitative Methods · Quantitative Biology 2016-01-20 Stephen Smith , Claudia Cianci , Ramon Grima

Living systems have evolved to efficiently consume available energy sources using an elaborate circuitry of chemical reactions which, puzzlingly, bear a strict restriction to asymmetric chiral configurations. While autocatalysis is known to…

Chemical Physics · Physics 2022-05-25 William D. Piñeros , Tsvi Tlusty

A key open question in the study of life is the origin of biomolecular homochirality: almost every life-form on Earth has exclusively levorotary amino acids and dextrorotary sugars. Will the same handedness be preferred if life is found…

Biomolecules · Quantitative Biology 2015-06-04 Marcelo Gleiser , Sara Imari Walker

Homochirality, i.e. the dominance across all living matter of one enantiomer over the other among chiral molecules, is thought to be a key step in the emergence of life. Building on ideas put forward by Frank and many others, we proposed…

Statistical Mechanics · Physics 2022-02-23 Gabin Laurent , David Lacoste , Pierre Gaspard

We analyse the effect of intrinsic fluctuations on the properties of bistable stochastic systems with time scale separation operating under1 quasi-steady state conditions. We first formulate a stochastic generalisation of the quasi-steady…

Biological Physics · Physics 2016-03-02 Roberto de la Cruz , Pilar Guerrero , Fabian Spill , Tomás Alarcón

Most biomolecules occur in mirror, or chiral, images of each other. However, life is homochiral: proteins contain almost exclusively levorotatory (L) amino acids, while only dextrorotatory (R) sugars appear in RNA and DNA. The mechanism…

Astrophysics · Physics 2009-06-23 Marcelo Gleiser , Joel Thorarinson , Sara Imari Walker

A recently proposed model of non-autocatalytic reactions in dipeptide reactions leading to spontaneous symmetry breaking and homochirality is examined. The model is governed by activation, polymerization, epimerization and depolymerization…

Biomolecules · Quantitative Biology 2007-11-01 Axel Brandenburg , Harry J. Lehto , Kirsi M. Lehto

To study the dynamics of chemical processes, we often adopt rate equations to observe the change in chemical concentrations. However, when the number of the molecules is small, the fluctuations cannot be neglected. We often study the…

Chemical Physics · Physics 2007-05-23 Yuichi Togashi , Kunihiko Kaneko

Chirality is a feature of many biological systems and much research has been focused on understanding the origin and implications of this property. Famously, sugars and amino acids found in nature are homochiral, i.e., chiral symmetry is…

Cell Behavior · Quantitative Biology 2023-07-28 Ludwig A. Hoffmann , Luca Giomi

In general, quantum fluctuations are suppressed in ferromagnetic materials because they admit a simple unfrustrated ground state, greatly limiting the scope of phenomena that can be observed in these materials. In this work, we show how…

Strongly Correlated Electrons · Physics 2026-05-11 Rokas Veitas , Ahmed Khalifa , Francisco Machado , Shubhayu Chatterjee

As an attempt to understand the homochirality of organic molecules in life, a chemical reaction model is proposed where the production of chiral monomers from achiral substrate is catalyzed by the polymers of the same enatiomeric type. This…

Biological Physics · Physics 2007-07-20 Yukio Saito , Hiroyuki Hyuga

Biomolecules that constitute life on Earth are chiral, but the precise mechanism by which homochirality emerged remains a mystery. In this work it is demonstrated that reactions of radical pairs, where one of the radical electron spins is…

Chemical Physics · Physics 2025-08-08 Thomas P Fay

Understanding interactions between chiral active particles -- self-propelling and self-rotating entities -- is crucial for uncovering how chiral active matter self-organizes into dynamic structures. Although fluctuation-induced forces in…

Soft Condensed Matter · Physics 2025-07-25 Hashem Fatemi , Hamidreza Khalilian , Jalal Sarabadani , M. Reza Shaebani

We extend our study of a simple model of biological coevolution to its statistical properties. Staring with a complete description in terms of a master equation, we provide its relation to the deterministic evolution equations used in…

Populations and Evolution · Quantitative Biology 2007-05-23 R. K. P. Zia , Per Arne Rikvold

Stochastic aspects of chemical reaction models related to the Soai reactions as well as to the homochirality in life are studied analytically and numerically by the use of the master equation and random walk model. For systems with a…

Statistical Mechanics · Physics 2007-07-20 Yukio Saito , Takeshi Sugimori , Hiroyuki Hyuga
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