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We present a novel approach to represent ecological systems using reaction networks, and show how a particular framework called Chemical Organization Theory (COT) sheds new light on the longstanding complexity-stability debate. Namely, COT…

Populations and Evolution · Quantitative Biology 2019-11-20 Tomas Veloz

Over the last decade, significant progress has been made in understanding complex biological systems, however there have been few attempts at incorporating this knowledge into nature inspired optimization algorithms. In this paper, we…

Neural and Evolutionary Computing · Computer Science 2009-07-03 James M. Whitacre , Ruhul A. Sarker , Q. Tuan Pham

We review the physical foundations of Landauer's Principle, which relates the loss of information from a computational process to an increase in thermodynamic entropy. Despite the long history of the Principle, its fundamental rationale and…

Emerging Technologies · Computer Science 2019-01-30 Michael P. Frank

The possible distinction between inanimate and living matter has been of interest to humanity since thousands of years. Clearly, such a rich question can not be answered in a single manner, and a plethora of approaches naturally do exist.…

Statistical Mechanics · Physics 2014-03-24 Constantino Tsallis

Following arXiv:2210.12963 [hep-th], we investigate aspects of the time evolution operator regarded as a density operator and associated entanglement-like structures in various quantum systems. These involve timelike separations and…

High Energy Physics - Theory · Physics 2024-04-29 K. Narayan , Hitesh K. Saini

Many entropy-conservative and entropy-stable (summarized as entropy-preserving) methods for hyperbolic conservation laws rely on Tadmor's theory for two-point entropy-preserving numerical fluxes and its higher-order extension via flux…

Numerical Analysis · Mathematics 2026-03-26 Marco Artiano , Hendrik Ranocha

This paper proposes a variational approach to describe the evolution of organization of complex systems from first principles, as increased efficiency of physical action. Most simply stated, physical action is the product of the energy and…

Adaptation and Self-Organizing Systems · Physics 2014-07-29 Georgi Yordanov Georgiev , Kaitlin Henry , Timothy Bates , Erin Gombos , Alexander Casey , Michael Daly , Amrit Vinod , Hyunseung Lee

Our planet is roughly closed to matter, but open to energy input from the sun. However, to harness this energy, organisms must transform matter from one chemical (redox) state to another. For example, photosynthetic organisms can capture…

Populations and Evolution · Quantitative Biology 2024-03-04 Akshit Goyal , Avi I. Flamholz , Alexander P. Petroff , Arvind Murugan

Life is a complex biological phenomenon represented by numerous chemical, physical and biological processes performed by a biothermodynamic system/cell/organism. Both living organisms and inanimate objects are subject to aging, a biological…

Other Quantitative Biology · Quantitative Biology 2018-01-25 Marko Popovic

The thermodynamic entropy of coarse-grained (CG) models stands as one of the most important properties for quantifying the missing information during the CG process and for establishing transferable (or extendible) CG interactions. However,…

Chemical Physics · Physics 2024-04-10 Jaehyeok Jin , David R. Reichman

Living systems maintain or increase local order by working against the Second Law of Thermodynamics. Thermodynamic consistency is restored as they dissipate heat, thereby increasing the net entropy of their environment. Recently introduced…

Biological Physics · Physics 2021-05-03 Dominic J. Skinner , Jörn Dunkel

We study open-ended evolution by focusing on computational and information-processing dynamics underlying major evolutionary transitions. In doing so, we consider biological organisms as hierarchical dynamical systems that generate…

Current mathematical frameworks for predicting the flux state and macromolecular composition of the cell do not rely on thermodynamic constraints to determine the spontaneous direction of reactions. These predictions may be biologically…

Optimization and Control · Mathematics 2020-08-14 Amir Akbari , Bernhard O. Palsson

Organisms are nonequilibrium, stationary systems self-organized via spontaneous symmetry breaking and undergoing metabolic cycles with broken detailed balance in the environment. The thermodynamic free-energy principle describes an…

Neurons and Cognition · Quantitative Biology 2022-11-24 Chang Sub Kim

Thermodynamic extensivity is commonly introduced as a postulate -- the homogeneity of degree one in thermodynamic potentials. We provide a constructive derivation of this property from microscopic conditions on the pair potential, without…

Statistical Mechanics · Physics 2026-05-19 Bob Osano

In a genetic algorithm, fluctuations of the entropy of a genome over time are interpreted as fluctuations of the information that the genome's organism is storing about its environment, being this reflected in more complex organisms. The…

Computational Engineering, Finance, and Science · Computer Science 2010-11-04 Manuel Cebrian , Manuel Alfonseca , Alfonso Ortega

The possibility that evolutionary forces -- together with a few fundamental factors such as thermodynamic constraints, specific computational features enabling information processing, and ecological processes -- might constrain the logic of…

Biological Physics · Physics 2025-12-30 Manlio De Domenico

Combining a spatiotemporal, multi-agent based model of a foraging ecosystem with linear, genetically programmed rules for the agents' behaviors results in implicit, endogenous, objective functions and selection algorithms based on "natural…

Neural and Evolutionary Computing · Computer Science 2023-06-01 John C Stevenson

One of the major challenges in biology concerns the integration of data across length and time scales into a consistent framework: how do macroscopic properties and functionalities arise from the molecular regulatory networks - and how can…

Computational Engineering, Finance, and Science · Computer Science 2015-10-20 Dagmar Iber , Zahra Karimaddini , Erkan Ünal

The managed-metabolism hypothesis suggests that a cooperation barrier must be overcome if self-producing chemical organizations are to transition from non-life to life. This barrier prevents un-managed, self-organizing, autocatalytic…

Populations and Evolution · Quantitative Biology 2018-08-06 John E. Stewart
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