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The ability to acquire large-scale recordings of neuronal activity in awake and unrestrained animals poses a major challenge for studying neural coding of animal behavior. We present a new instrument capable of recording intracellular…

Neurons and Cognition · Quantitative Biology 2015-12-31 Jeffrey P. Nguyen , Frederick B. Shipley , Ashley N. Linder , George S. Plummer , Joshua W. Shaevitz , Andrew M. Leifer

Quantitative models of associative learning that explain the behavior of real animals with high precision have turned out very difficult to construct. We do this in the context of the dynamics of the thermal preference of C. elegans. For…

Biological Physics · Physics 2022-06-02 Ahmed Roman , Konstantine Palanski , Ilya Nemenman , William S Ryu

The neural dynamics of the nematode C. elegans are experimentally low-dimensional and correspond to discrete behavioral states, where previous modeling work has found neural proxies for some of these states. Experimental results further…

Neurons and Cognition · Quantitative Biology 2015-09-04 James Kunert , Eli Shlizerman , Andrew Walker , J. Nathan Kutz

Advances in optical neuroimaging techniques now allow neural activity to be recorded with cellular resolution in awake and behaving animals. Brain motion in these recordings pose a unique challenge. The location of individual neurons must…

Neurons and Cognition · Quantitative Biology 2017-05-22 Jeffrey P. Nguyen , Ashley N. Linder , George S. Plummer , Joshua W. Shaevitz , Andrew M. Leifer

We exploit flow propagation on the directed neuronal network of the nematode Caenorhabditis elegans to reveal dynamically relevant features of its connectome. We find flow-based groupings of neurons at different levels of granularity, which…

Neurons and Cognition · Quantitative Biology 2016-08-09 Karol A. Bacik , Michael T. Schaub , Mariano Beguerisse-Díaz , Yazan N. Billeh , Mauricio Barahona

The effects of fluid elasticity on the swimming behavior of the nematode \emph{Caenorhabditis elegans} are experimentally investigated by tracking the nematode's motion and measuring the corresponding velocity fields. We find that fluid…

Fluid Dynamics · Physics 2015-05-27 Xiaoning Shen , P. E. Arratia

Recent efforts in neuroscience research seek to obtain detailed anatomical neuronal wiring maps as well as information on how neurons in these networks engage in dynamic activities. Although the entire connectivity map of the nervous system…

Neurons and Cognition · Quantitative Biology 2014-06-09 Tina Schrödel , Robert Prevedel , Karin Aumayr , Manuel Zimmer , Alipasha Vaziri

Every year, plant parasitic nematodes, one of the major groups of plant pathogens, cause a significant loss of crops worldwide. To mitigate crop yield losses caused by nematodes, an efficient nematode monitoring method is essential for…

Computer Vision and Pattern Recognition · Computer Science 2024-05-01 Zhipeng Yuan , Nasamu Musa , Katarzyna Dybal , Matthew Back , Daniel Leybourne , Po Yang

The pharynx of the nematode Caenorhabditis elegans is a neuromuscular pump that exhibits two typical motions: pumping and peristalsis. While the dynamics of these motions are well characterized, the underlying mechanisms generating most of…

Neurons and Cognition · Quantitative Biology 2019-03-29 Dana Sherman , David Harel

Despite recent interest in reconstructing neuronal networks, complete wiring diagrams on the level of individual synapses remain scarce and the insights into function they can provide remain unclear. Even for Caenorhabditis elegans, whose…

Neurons and Cognition · Quantitative Biology 2011-02-07 Lav R. Varshney , Beth L. Chen , Eric Paniagua , David H. Hall , Dmitri B. Chklovskii

Walking animals, like stick insects, cockroaches or ants, demonstrate a fascinating range of locomotive abilities and complex behaviors. The locomotive behaviors can consist of a variety of walking patterns along with adaptation that allow…

Neural and Evolutionary Computing · Computer Science 2016-08-08 Sakyasingha Dasgupta , Dennis Goldschmidt , Florentin Wörgötter , Poramate Manoonpong

To establish the relationship between locomotory behavior and dynamics of neural circuits in the nematode C. elegans we combined molecular and theoretical approaches. In particular, we quantitatively analyzed the motion of C. elegans with…

Neurons and Cognition · Quantitative Biology 2008-06-10 Jan Karbowski , Gary Schindelman , Chris J. Cronin , Adeline Seah , Paul W. Sternberg

Motion perception is a critical capability determining a variety of aspects of insects' life, including avoiding predators, foraging and so forth. A good number of motion detectors have been identified in the insects' visual pathways.…

Computer Vision and Pattern Recognition · Computer Science 2019-04-04 Qinbing Fu , Hongxin Wang , Cheng Hu , Shigang Yue

Studying animal locomotion improves our understanding of motor control and aids in the treatment of motor impairment. Mice are a premier model of human disease and are the model system of choice for much of basic neuroscience. High frame…

Computer Vision and Pattern Recognition · Computer Science 2018-02-08 Omid Haji Maghsoudi , Mahdi Alizadeh

This study introduces an artificial neural network (ANN) for image classification task, inspired by the aversive olfactory learning circuits of the nematode Caenorhabditis elegans (C. elegans). Despite the remarkable performance of ANNs in…

Neural and Evolutionary Computing · Computer Science 2024-09-13 Xuebin Wang , Chunxiuzi Liu , Meng Zhao , Ke Zhang , Zengru Di , He Liu

In the fluid dynamics video, we present a microfluidic device to measure the propulsive power of nematodes. The device consists of a tapered conduit filled with aqueous solution. The conduit is subjected to a DC electric field with the…

Fluid Dynamics · Physics 2011-10-18 J. Yuan , H-S Chuang , M. Gnatt , D. M. Raizen , H. H. Bau

Various microorganisms and some mammalian cells are able to swim in viscous fluids by performing nonreciprocal body deformations, such as rotating attached flagella or by distorting their entire body. In order to perform chemotaxis, i.e. to…

Biological Physics · Physics 2021-05-06 Benedikt Hartl , Maximilian Hübl , Gerhard Kahl , Andreas Zöttl

Self-propelling organisms locomote via generation of patterns of self-deformation. Despite the diversity of body plans, internal actuation schemes and environments in limbless vertebrates and invertebrates, such organisms often use similar…

Computer-aided analysis of biological microscopy data has seen a massive improvement with the utilization of general-purpose deep learning techniques. Yet, in microscopy studies of multi-organism systems, the problem of collision and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-09 Albert Alonso , Julius B. Kirkegaard

Field-captured video facilitates detailed studies of spatio-temporal aspects of animal locomotion, decision-making and environmental interactions including predator-prey relationships and habitat utilisation. But even though data capture is…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Malika Nisal Ratnayake , Lex Gallon , Adel N. Toosi , Alan Dorin