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The principles of neural encoding and computations are inherently collective and usually involve large populations of interacting neurons with highly correlated activities. While theories of neural function have long recognized the…

Neurons and Cognition · Quantitative Biology 2019-05-14 Christophe Gardella , Olivier Marre , Thierry Mora

The prediction of the three-dimensional structures of the native state of proteins from the sequences of their amino acids is one of the most important challenges in molecular biology. An essential ingredient to solve this problem within…

Statistical Mechanics · Physics 2007-05-23 Cristian Micheletti , Flavio Seno , Jayanth Banavar , Amos Maritan

The network paradigm is increasingly used to describe the dynamics of complex systems. Here we review the current results and propose future development areas in the assessment of perturbation waves, i.e. propagating structural changes in…

Molecular Networks · Quantitative Biology 2009-04-23 Miklos A. Antal , Csaba Bode , Peter Csermely

Novel experimental techniques reveal the simultaneous activity of larger and larger numbers of neurons. As a result there is increasing interest in the structure of cooperative -- or correlated -- activity in neural populations, and in the…

Neurons and Cognition · Quantitative Biology 2015-05-30 James Trousdale , Yu Hu , Eric Shea-Brown , Krešimir Josić

We analyze the synchronous firings of the salamander ganglion cells from the perspective of the complex network viewpoint where the network's links reflect the correlated behavior of firings. We study the time-aggregated properties of the…

Biological Physics · Physics 2009-05-20 Błażej Ruszczycki , Zhenyuan Zhao , Neil F. Johnson

Couplings play a central role in the analysis of Markov chain Monte Carlo algorithms and appear increasingly often in the algorithms themselves, e.g. in convergence diagnostics, parallelization, and variance reduction techniques. Existing…

Computation · Statistics 2020-10-20 John O'Leary , Guanyang Wang , Pierre E. Jacob

Dynamic cluster Monte Carlo calculations for the doped two-dimensional Hubbard model are used to study the irreducible particle-particle vertex responsible for $d_{x^2-y^2}$ pairing in this model. This vertex increases with increasing…

Superconductivity · Physics 2009-11-11 T. A. Maier , M. S. Jarrell , D. J. Scalapino

Couplings play a central role in the analysis of Markov chain convergence and in the construction of novel Markov chain Monte Carlo estimators, diagnostics, and variance reduction techniques. The set of possible couplings is often…

Statistics Theory · Mathematics 2023-01-09 John O'Leary , Guanyang Wang

Despite their widespread utility across domains, basic network models face fundamental limitations when applied to complex biological systems, particularly in neuroscience. This paper critically examines these limitations and explores…

Other Quantitative Biology · Quantitative Biology 2024-11-07 Luiz Pessoa

Interconnected ensembles of biological entities are perhaps some of the most complex systems that modern science has encountered so far. In particular, scientists have concentrated on understanding how the complexity of the interacting…

Pattern Formation and Solitons · Physics 2020-11-18 Bram A. Siebert , Cameron L. Hall , James P. Gleeson , Malbor Asllani

Proteins participating in a protein-protein interaction network can be grouped into homology classes following their common ancestry. Proteins added to the network correspond to genes added to the classes, so that the dynamics of the two…

Molecular Networks · Quantitative Biology 2013-05-30 Arianna Bottinelli , Bruno Bassetti , Marco Cosentino Lagomarsino , Marco Gherardi

Reciprocating interactions represent a central feature of all human exchanges. They have been the target of various recent experiments, with healthy participants and psychiatric populations engaging as dyads in multi-round exchanges such as…

Machine Learning · Statistics 2015-06-23 Andreas Hula , P. Read Montague , Peter Dayan

Many complex systems can be represented as networks composed by distinct layers, interacting and depending on each others. For example, in biology, a good description of the full protein-protein interactome requires, for some organisms, up…

Physics and Society · Physics 2015-04-24 M. De Domenico , V. Nicosia , A. Arenas , V. Latora

The principles underlying protein folding remains one of Nature's puzzles with important practical consequences for Life. An approach that has gathered momentum since the late 1990's, looks at protein hetero-polymers and their folding…

Computational Engineering, Finance, and Science · Computer Science 2011-10-05 Susan Khor

We analyze the problem of high-order polynomial approximation from a many-body physics perspective, and demonstrate the descriptive power of entanglement entropy in capturing model capacity and task complexity. Instantiated with a…

Quantum Physics · Physics 2022-04-19 Tong Yang

Photons strongly coupled to material systems constitute a novel system for studying the dynamics of non-equilibrium quantum many-body systems. We give a fully analytical description of the dynamics of photons coupled to a one-dimensional…

Quantum Physics · Physics 2023-01-04 Björn Schrinski , Anders S. Sørensen

Network theorists have developed methods to characterize the complex interactions in natural phenomena. The structure of the network of interactions between proteins is important in the field of proteomics, and has been subject to intensive…

Molecular Networks · Quantitative Biology 2016-09-07 Allan A. Zea , Antonio Rueda-Toicen

The potential effects of conservation actions on threatened species can be predicted using ensemble ecosystem models by forecasting populations with and without intervention. These model ensembles commonly assume stable coexistence of…

Populations and Evolution · Quantitative Biology 2024-03-22 Sarah A. Vollert , Christopher Drovandi , Matthew P. Adams

In this article, we report a fully ab initio variational Monte Carlo study of the linear, and periodic chain of Hydrogen atoms, a prototype system providing the simplest example of strong electronic correlation in low dimensions. In…

Strongly Correlated Electrons · Physics 2015-05-30 Lorenzo Stella , Claudio Attaccalite , Sandro Sorella , Angel Rubio

Pairing correlations in nuclei play a decisive role in determining nuclear drip-lines, binding energies, and many collective properties. In this work a new Configuration-Space Monte-Carlo (CSMC) method for treating nuclear pairing…

Nuclear Theory · Physics 2015-03-23 Mark Lingle , Alexander Volya