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We present a unifying approach to quantum error correcting code design that encompasses additive (stabilizer) codes, as well as all known examples of nonadditive codes with good parameters. We use this framework to generate new codes with…

Quantum Physics · Physics 2009-02-19 Andrew Cross , Graeme Smith , John A. Smolin , Bei Zeng

We calculate the optimality of a doublet precursor to the canonical genetic code with respect to mitigating the effects of point mutations and compare our results to corresponding ones for the canonical genetic code. We find that the…

Other Quantitative Biology · Quantitative Biology 2013-05-29 Thomas Butler , Nigel Goldenfeld

Although several synonymous codons can encode the same aminoacid, this symmetry is generally broken in natural genetic systems. In this article, we show that the symmetry breaking can result from selective pressures due to the violation of…

adap-org · Physics 2008-02-03 S. Vera , H. Waelbroeck

We demonstrate how a genetic algorithm solves the problem of minimizing the resources used for network coding, subject to a throughput constraint, in a multicast scenario. A genetic algorithm avoids the computational complexity that makes…

Neural and Evolutionary Computing · Computer Science 2007-05-23 Minkyu Kim , Varun Aggarwal , Una-May O'Reilly , Muriel Medard , Wonsik Kim

The codons, sixtyfour in number, are distributed over the coding parts of DNA sequences. The distribution function is the plot of frequency-versus-rank of the codons. These distributions are characterised by parameters that are almost…

Biological Physics · Physics 2009-11-07 A. Som , S. Chattopadhyay , J. Chakrabarti , D. Bandyopadhyay

Gene expression levels carry information about signals that have functional significance for the organism. Using the gap gene network in the fruit fly embryo as an example, we show how this information can be decoded, building a dictionary…

Molecular Networks · Quantitative Biology 2024-01-23 Mariela D. Petkova , Gašper Tkačik , William Bialek , Eric F. Wieschaus , Thomas Gregor

Stopping sets play a crucial role in failure events of iterative decoders over a binary erasure channel (BEC). The $\ell$-th stopping redundancy is the minimum number of rows in the parity-check matrix of a code, which contains no stopping…

Information Theory · Computer Science 2018-10-02 Yauhen Yakimenka , Vitaly Skachek , Irina E. Bocharova , Boris D. Kudryashov

Graph codes play an important role in photonic quantum technologies as they provide significant protection against qubit loss, a dominant noise mechanism. Here, we develop methods to analyse and optimise measurement-based tolerance to qubit…

Quantum Physics · Physics 2022-12-12 Tom J. Bell , Love A. Pettersson , Stefano Paesani

In this work, we investigate a challenging problem, which has been considered to be an important criterion in designing codewords for DNA computing purposes, namely secondary structure avoidance in single-stranded DNA molecules. In short,…

Information Theory · Computer Science 2023-02-28 Tuan Thanh Nguyen , Kui Cai , Han Mao Kiah , Duc Tu Dao , Kees A. Schouhamer Immink

This paper studies two problems that are motivated by the novel recent approach of composite DNA that takes advantage of the DNA synthesis property which generates a huge number of copies for every synthesized strand. Under this paradigm,…

Information Theory · Computer Science 2025-05-15 Tomer Cohen , Eitan Yaakobi

The genesis of the stand genetic code is considered as a result of a fusion of two AU- and GC-codes distributed in two dominant and two recessive domains. The fusion of these codes is described with simple empirical rules. This formal…

Other Quantitative Biology · Quantitative Biology 2020-04-21 A. Nesterov-Mueller , R. Popov

A (tandem) duplication of length $ k $ is an insertion of an exact copy of a substring of length $ k $ next to its original position. This and related types of impairments are of relevance in modeling communication in the presence of…

Information Theory · Computer Science 2020-08-13 Mladen Kovačević , Vincent Y. F. Tan

Evolutionary theorizing resembles building an aircraft while also piloting it; new results change the scaffold for older ideas, requiring revised strategy to remain airborne. A calculated kinetic pathway exists that, under explicit…

Populations and Evolution · Quantitative Biology 2024-10-11 Michael Yarus

Encoding data as a set of unordered strings is receiving great attention as it captures one of the basic features of DNA storage systems. However, the challenge of constructing optimal redundancy codes for this channel remained elusive. In…

Information Theory · Computer Science 2023-08-16 Jin Sima , Netanel Raviv , Jehoshua Bruck

When polygenic traits are under stabilizing selection, many different combinations of alleles allow close adaptation to the optimum. If alleles have equal effects, all combinations that result in the same deviation from the optimum are…

Populations and Evolution · Quantitative Biology 2014-04-04 Harold P. de Vladar , Nick Barton

The rank-modulation scheme has been recently proposed for efficiently storing data in nonvolatile memories. Error-correcting codes are essential for rank modulation, however, existing results have been limited. In this work we explore a new…

Information Theory · Computer Science 2013-10-28 Hongchao Zhou , Moshe Schwartz , Anxiao Jiang , Jehoshua Bruck

We consider the problem of slotted asynchronous coded communication, where in each time frame (slot), the transmitter is either silent or transmits a codeword from a given (randomly selected) codebook. The task of the decoder is to decide…

Information Theory · Computer Science 2013-08-22 Neri Merhav

This note represents the further progress in understanding the determination of the genetic code by Golden mean (Rakocevic, 1998). Three classes of amino acids that follow from this determination (the 7 "golden" amino acids, 7 of their…

Biomolecules · Quantitative Biology 2009-03-25 Miloje M. Rakocevic

We generalize the notion of the stopping redundancy in order to study the smallest size of a trapping set in Tanner graphs of linear block codes. In this context, we introduce the notion of the trapping redundancy of a code, which…

Information Theory · Computer Science 2016-11-17 Stefan Laendner , Thorsten Hehn , Olgica Milenkovic , Johannes B. Huber

Due to its high data density and longevity, DNA is considered a promising medium for satisfying ever-increasing data storage needs. However, the diversity of errors that occur in DNA sequences makes efficient error-correction a challenging…

Information Theory · Computer Science 2020-11-12 Yuanyuan Tang , Farzad Farnoud
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