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Biological networks have so many possible states that exhaustive sampling is impossible. Successful analysis thus depends on simplifying hypotheses, but experiments on many systems hint that complicated, higher order interactions among…

Neurons and Cognition · Quantitative Biology 2009-11-11 Elad Schneidman , Michael J. Berry , Ronen Segev , William Bialek

Inverse statistical physics aims at inferring models compatible with a set of empirical averages estimated from a high-dimensional dataset of independently distributed equilibrium configurations of a given system. However, in several…

Disordered Systems and Neural Networks · Physics 2021-02-12 Edwin Rodriguez Horta , Alejandro Lage , Martin Weigt , Pierre Barrat-Charlaix

We study inference and reconstruction of couplings in a partially observed kinetic Ising model. With hidden spins, calculating the likelihood of a sequence of observed spin configurations requires performing a trace over the configurations…

Disordered Systems and Neural Networks · Physics 2021-04-13 Benjamin Dunn , Yasser Roudi

We consider stochastic systems of interacting particles or agents, with dynamics determined by an interaction kernel which only depends on pairwise distances. We study the problem of inferring this interaction kernel from observations of…

Statistics Theory · Mathematics 2020-07-31 Fei Lu , Mauro Maggioni , Sui Tang

We study the Closest Pair Problem in Hamming metric, which asks to find the pair with the smallest Hamming distance in a collection of binary vectors. We give a new randomized algorithm for the problem on uniformly random input…

Data Structures and Algorithms · Computer Science 2021-12-08 Andre Esser , Robert Kübler , Floyd Zweydinger

In computational design and fabrication, neural networks are becoming important surrogates for bulky forward simulations. A long-standing, intertwined question is that of inverse design: how to compute a design that satisfies a desired…

Graphics · Computer Science 2022-08-30 Navid Ansari , Hans-Peter Seidel , Vahid Babaei

This work is focussed on the inversion task of inferring the distribution over parameters of interest leading to multiple sets of observations. The potential to solve such distributional inversion problems is driven by increasing…

Machine Learning · Statistics 2026-05-06 Arnaud Vadeboncoeur , Mark Girolami , Andrew M. Stuart

Success in modeling complex phenomena such as human perception hinges critically on the availability of data and computational power. Significant progress has been made in modeling such phenomena using probabilistic methods, particularly in…

Data Analysis, Statistics and Probability · Physics 2019-02-20 Danh-Tai Hoang , Juyong Song , Vipul Periwal , Junghyo Jo

Ising models originated in statistical physics and are widely used in modeling spatial data and computer vision problems. However, statistical inference of this model remains challenging due to intractable nature of the normalizing constant…

Methodology · Statistics 2021-09-06 Minwoo Kim , Shrijita Bhattacharya , Tapabrata Maiti

Network psychometrics conceptualises psychological constructs as emergent properties of systems of interacting variables. Energy-based probabilistic models have gained popularity as models of these interactions, but their psychometric…

Data Analysis, Statistics and Probability · Physics 2026-05-29 Arianna Armanetti , Luca Cecchetti , Paolo Sarti , Diego Garlaschelli , Miguel Ibáñez-Berganza

We test four fast mean field type algorithms on Hopfield networks as an inverse Ising problem. The equilibrium behavior of Hopfield networks is simulated through Glauber dynamics. In the low temperature regime, the simulated annealing…

Disordered Systems and Neural Networks · Physics 2013-05-29 Haiping Huang

Bayesian observer and actor models have provided normative explanations for many behavioral phenomena in perception, sensorimotor control, and other areas of cognitive science and neuroscience. They attribute behavioral variability and…

Machine Learning · Computer Science 2025-02-03 Dominik Straub , Tobias F. Niehues , Jan Peters , Constantin A. Rothkopf

The Ising model is a useful tool for studying complex interactions within a system. The estimation of such a model, however, is rather challenging, especially in the presence of high-dimensional parameters. In this work, we propose…

Statistics Theory · Mathematics 2012-08-20 Lingzhou Xue , Hui Zou , Tianxi Cai

We consider the problem of inferring the interactions between a set of N binary variables from the knowledge of their frequencies and pairwise correlations. The inference framework is based on the Hopfield model, a special case of the Ising…

Statistical Mechanics · Physics 2015-05-27 Simona Cocco , Remi Monasson , Vitor Sessak

Generalized linear models are one of the most efficient paradigms for predicting the correlated stochastic activity of neuronal networks in response to external stimuli, with applications in many brain areas. However, when dealing with…

Disordered Systems and Neural Networks · Physics 2020-11-17 Gabriel Mahuas , Giulio Isacchini , Olivier Marre , Ulisse Ferrari , Thierry Mora

To construct models of large, multivariate complex systems, such as those in biology, one needs to constrain which variables are allowed to interact. This can be viewed as detecting "local" structures among the variables. In the context of…

Data Analysis, Statistics and Probability · Physics 2023-10-19 Mahajabin Rahman , Ilya Nemenman

We derive a parallel sampling algorithm for computational inverse problems that present an unknown linear forcing term and a vector of nonlinear parameters to be recovered. It is assumed that the data is noisy and that the linear part of…

Numerical Analysis · Mathematics 2022-03-24 Darko Volkov

In this work we consider the problem of extracting a set of interaction parameters from an high-dimensional dataset describing T independent configurations of a complex system composed of N binary units. This problem is formulated in the…

Statistical Mechanics · Physics 2013-11-04 Iacopo Mastromatteo

Maximum entropy models are the least structured probability distributions that exactly reproduce a chosen set of statistics measured in an interacting network. Here we use this principle to construct probabilistic models which describe the…

Neurons and Cognition · Quantitative Biology 2014-01-28 Gašper Tkačik , Olivier Marre , Dario Amodei , Elad Schneidman , William Bialek , Michael J Berry

Hamiltonian learning (HL), enabling precise estimation of system parameters and underlying dynamics, plays a critical role in characterizing quantum systems. However, conventional HL methods face challenges in noise robustness and resource…

Quantum Physics · Physics 2025-11-07 Jie Liu , Xin Wang