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We consider the problem of learning the underlying graph of an unknown Ising model on p spins from a collection of i.i.d. samples generated from the model. We suggest a new estimator that is computationally efficient and requires a number…

Machine Learning · Computer Science 2017-04-17 Marc Vuffray , Sidhant Misra , Andrey Y. Lokhov , Michael Chertkov

The pairwise maximum entropy model, also known as the Ising model, has been widely used to analyze the collective activity of neurons. However, controversy persists in the literature about seemingly inconsistent findings, whose significance…

Disordered Systems and Neural Networks · Physics 2019-03-13 Cristian Zanoci , Nima Dehghani , Max Tegmark

Reconstruction of structure and parameters of an Ising model from binary samples is a problem of practical importance in a variety of disciplines, ranging from statistical physics and computational biology to image processing and machine…

Statistical Mechanics · Physics 2017-12-27 Andrey Y. Lokhov , Marc Vuffray , Sidhant Misra , Michael Chertkov

Discovering interaction effects on a response of interest is a fundamental problem faced in biology, medicine, economics, and many other scientific disciplines. In theory, Bayesian methods for discovering pairwise interactions enjoy many…

Computation · Statistics 2022-11-15 Raj Agrawal , Jonathan H. Huggins , Brian Trippe , Tamara Broderick

Ising models are a simple generative approach to describing interacting binary variables. They have proven useful in a number of biological settings because they enable one to represent observed many-body correlations as the separable…

Machine Learning · Computer Science 2021-09-10 Emma Slade , Sonya Kiselgof , Lena Granovsky , Jeremy L. England

Two recent streams of work suggest that pairwise interactions may be sufficient to capture the complexity of biological systems ranging from protein structure to networks of neurons. In one approach, possible amino acid sequences in a…

Quantitative Methods · Quantitative Biology 2007-12-31 William Bialek , Rama Ranganathan

Randomly coupled Ising spins constitute the classical model of collective phenomena in disordered systems, with applications covering ferromagnetism, combinatorial optimization, protein folding, stock market dynamics, and social dynamics.…

Disordered Systems and Neural Networks · Physics 2016-08-24 David Dahmen , Hannah Bos , Moritz Helias

Correlations between two variables of a high-dimensional system can be indicative of an underlying interaction, but can also result from indirect effects. Inverse Ising inference is a method to distinguish one from the other. Essentially,…

Populations and Evolution · Quantitative Biology 2014-12-10 Benedikt Obermayer , Erel Levine

We propose a novel approach to the inverse Ising problem which employs the recently introduced Density Consistency approximation (DC) to determine the model parameters (couplings and external fields) maximizing the likelihood of given…

Statistical Mechanics · Physics 2021-04-01 Alfredo Braunstein , Giovanni Catania , Luca Dall'Asta , Anna Paola Muntoni

We present a procedure to solve the inverse Ising problem, that is to find the interactions between a set of binary variables from the measure of their equilibrium correlations. The method consists in constructing and selecting specific…

Disordered Systems and Neural Networks · Physics 2015-05-30 Simona Cocco , Rémi Monasson

The inverse Ising model is used in computational neuroscience to infer probability distributions of the synchronous activity of large neuronal populations. This method allows for finding the Boltzmann distribution with single neuron biases…

Neurons and Cognition · Quantitative Biology 2022-07-27 Geoffroy Delamare , Ulisse Ferrari

The Ising Model has recently received much attention for the statistical description of neural spike train data. In this paper, we propose and demonstrate its use for building decoders capable of predicting, on a millisecond timescale, the…

Neurons and Cognition · Quantitative Biology 2011-05-24 Michael T. Schaub , Simon R. Schultz

The Ising model was originally developed to model magnetisation of solids in statistical physics. As a network of binary variables with the probability of becoming 'active' depending only on direct neighbours, the Ising model appears…

Statistics Theory · Mathematics 2018-07-31 Lourens Waldorp , Maarten Marsman , Gunter Maris

We study Ising chains with arbitrary multispin finite-range couplings, providing an explicit solution of the associated inverse Ising problem, i.e. the problem of inferring the values of the coupling constants from the correlation…

Statistical Mechanics · Physics 2011-11-16 Giacomo Gori , Andrea Trombettoni

As a problem in data science the inverse Ising (or Potts) problem is to infer the parameters of a Gibbs-Boltzmann distributions of an Ising (or Potts) model from samples drawn from that distribution. The algorithmic and computational…

Other Statistics · Statistics 2020-02-14 Hong-Li Zeng , Erik Aurell

We introduce and study methods for inferring and learning from correspondences among neurons. The approach enables alignment of data from distinct multiunit studies of nervous systems. We show that the methods for inferring correspondences…

Neurons and Cognition · Quantitative Biology 2015-01-28 Ashish Kapoor , E. Paxon Frady , Stefanie Jegelka , William B. Kristan , Eric Horvitz

The models in statistical physics such as an Ising model offer a convenient way to characterize stationary activity of neural populations. Such stationary activity of neurons may be expected for recordings from in vitro slices or…

Neurons and Cognition · Quantitative Biology 2017-05-05 Christian Donner , Klaus Obermayer , Hideaki Shimazaki

Financial markets are a classical example of complex systems as they comprise many interacting stocks. As such, we can obtain a surprisingly good description of their structure by making the rough simplification of binary daily returns.…

Statistical Finance · Quantitative Finance 2014-01-28 Thomas Bury

Reconstructing the structural connectivity between interacting units from observed activity is a challenge across many different disciplines. The fundamental first step is to establish whether or to what extent the interactions between the…

Neurons and Cognition · Quantitative Biology 2016-11-02 Elliot A. Martin , Jaroslav Hlinka , Jörn Davidsen

In many tasks, in particular in natural science, the goal is to determine hidden system parameters from a set of measurements. Often, the forward process from parameter- to measurement-space is a well-defined function, whereas the inverse…