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We develop methods for analyzing discrete multivariate longitudinal data and apply them to functional disability data on the U.S. elderly population from the National Long Term Care Survey (NLTCS), 1982-2004. Our models build on a Mixed…

Applications · Statistics 2015-03-05 Daniel Manrique-Vallier

This work focuses on the mixed membership models for multivariate categorical data widely used for analyzing survey responses and population genetics data. These grade of membership (GoM) models offer rich modeling power but present…

Methodology · Statistics 2024-12-30 Ling Chen , Chengzhu Huang , Yuqi Gu

Grade of Membership (GoM) models are popular individual-level mixture models for multivariate categorical data. GoM allows each subject to have mixed memberships in multiple extreme latent profiles. Therefore GoM models have a richer…

Methodology · Statistics 2025-01-01 Ling Chen , Yuqi Gu

Latent class analysis, a fundamental problem in categorical data analysis, often encounters overlapping latent classes that introduce further challenges. This paper presents a solution to this problem by focusing on finding latent mixed…

Social and Information Networks · Computer Science 2024-06-06 Huan Qing

Grade of membership (GoM) analysis was introduced in 1974 as a means of analyzing multivariate categorical data. Since then, it has been successfully applied to many problems. The primary goal of GoM analysis is to derive properties of…

Statistics Theory · Mathematics 2007-06-13 Mikhail Kovtun , Igor Akushevich , Kenneth G. Manton , H. Dennis Tolley

Consider a group of individuals (subjects) participating in the same psychological tests with numerous questions (items) at different times, where the choices of each item have an implicit ordering. The observed responses can be recorded in…

Methodology · Statistics 2026-02-26 Huan Qing

As the aging population grows, particularly for the baby boomer generation, the United States is witnessing a significant increase in the elderly population experiencing multifunctional disabilities. These disabilities, stemming from a…

Machine Learning · Computer Science 2024-04-09 Suiyao Chen , Xinyi Liu , Yulei Li , Jing Wu , Handong Yao

Mixed Membership Models (MMMs) are a popular family of latent structure models for complex multivariate data. Instead of forcing each subject to belong to a single cluster, MMMs incorporate a vector of subject-specific weights…

Methodology · Statistics 2023-02-16 Yuqi Gu , Elena A. Erosheva , Gongjun Xu , David B. Dunson

Mixed membership models, or partial membership models, are a flexible unsupervised learning method that allows each observation to belong to multiple clusters. In this paper, we propose a Bayesian mixed membership model for functional data.…

Literature on machine learning for multiple sclerosis has primarily focused on the use of neuroimaging data such as magnetic resonance imaging and clinical laboratory tests for disease identification. However, studies have shown that these…

We propose a comprehensive Bayesian approach for graphical model determination in observational studies that can accommodate binary, ordinal or continuous variables simultaneously. Our new models are called copula Gaussian graphical models…

Applications · Statistics 2011-08-09 Adrian Dobra , Alex Lenkoski

Point and interval estimation of future disability inception and recovery rates are predominantly carried out by combining generalized linear models (GLM) with time series forecasting techniques into a two-step method involving parameter…

Applications · Statistics 2014-12-24 Boualem Djehiche , Björn Löfdahl

Variational inference is a general approach for approximating complex density functions, such as those arising in latent variable models, popular in machine learning. It has been applied to approximate the maximum likelihood estimator and…

Methodology · Statistics 2018-04-19 Yen-Chi Chen , Y. Samuel Wang , Elena A. Erosheva

Multiple Sclerosis (MS) is a chronic disease characterized by progressive or alternate impairment of neurological functions (motor, sensory, visual, and cognitive). Predicting disease progression with a probabilistic and time-dependent…

The Grade of Membership (GoM) model, which allows subjects to belong to multiple latent classes, is a powerful tool for inferring latent classes in categorical data. However, its application is limited to categorical data with nonnegative…

Social and Information Networks · Computer Science 2025-09-01 Huan Qing

A wide range of Bayesian models have been proposed for data that is divided hierarchically into groups. These models aim to cluster the data at different levels of grouping, by assigning a mixture component to each datapoint, and a mixture…

Machine Learning · Computer Science 2015-04-21 Adway Mitra

Physical activity is crucial for human health. With the increasing availability of large-scale mobile health data, strong associations have been found between physical activity and various diseases. However, accurately capturing this…

Methodology · Statistics 2026-01-19 Xiaojing Sun , Bingxin Zhao , Fei Xue

We describe and analyze a broad class of mixture models for real-valued multivariate data in which the probability density of observations within each component of the model is represented as an arbitrary combination of basis functions.…

Methodology · Statistics 2025-02-28 M. E. J. Newman

Multivariate bounded discrete data arises in many fields. In the setting of dementia studies, such data is collected when individuals complete neuropsychological tests. We outline a modeling and inference procedure that can model the joint…

Methodology · Statistics 2026-02-10 Daniel Suen , Yen-Chi Chen

This article considers the estimation of the number of severely disabled people using data from the Italian survey on Health Conditions and Appeal to Medicare. Disability is indirectly measured using a set of categorical items, which survey…

Applications · Statistics 2015-08-25 Enrico Fabrizi , Giorgio E. Montanari , Maria Giovanna Ranalli
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