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Data augmentation is one of the most effective techniques to improve the generalization performance of deep neural networks. Yet, despite often facing limited data availability in medical image analysis, it is frequently underutilized. This…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Adam Tupper , Christian Gagné

We present a method for handling dose constraints as part of a convex programming framework for inverse treatment planning. Our method uniformly handles mean dose, maximum dose, minimum dose, and dose-volume (i.e., percentile) constraints…

Medical Physics · Physics 2019-03-05 Anqi Fu , Baris Ungun , Lei Xing , Stephen Boyd

A large body of previous machine learning methods for ultrasound-based prostate cancer detection classify small regions of interest (ROIs) of ultrasound signals that lie within a larger needle trace corresponding to a prostate tissue biopsy…

Image and Video Processing · Electrical Eng. & Systems 2023-03-06 Mahdi Gilany , Paul Wilson , Andrea Perera-Ortega , Amoon Jamzad , Minh Nguyen Nhat To , Fahimeh Fooladgar , Brian Wodlinger , Purang Abolmaesumi , Parvin Mousavi

The field of Radiation Oncology is uniquely positioned to benefit from the use of artificial intelligence to fully automate the creation of radiation treatment plans for cancer therapy. This time-consuming and specialized task combines…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Kuancheng Wang , Hai Siong Tan , Rafe Mcbeth

Data augmentation refers to a group of techniques whose goal is to battle limited amount of available data to improve model generalization and push sample distribution toward the true distribution. While different augmentation strategies…

Quantitative Methods · Quantitative Biology 2020-06-03 Ruqian Hao , Khashayar Namdar , Lin Liu , Masoom A. Haider , Farzad Khalvati

Many diagnostic and therapeutic clinical tasks for prostate cancer increasingly rely on multi-parametric MRI. Automating these tasks is challenging because they necessitate expert interpretations, which are difficult to scale to capitalise…

Chemotherapy is one of the primary modalities of cancer treatment. Chemotherapy drug administration is a complex problem that often requires expensive clinical trials to evaluate potential regimens. One way to alleviate this burden and…

Optimization and Control · Mathematics 2021-11-04 Temitayo Ajayi , Seyedmohammadhossein Hosseinian , Andrew J. Schaefer , Clifton D. Fuller

AI-assisted imaging made substantial advances in tumor diagnosis and management. However, a major barrier to developing robust oncology foundation models is the scarcity of large-scale, high-quality annotated datasets, which are limited by…

The challenge of removing cancerous cells lies in the limitation of organ at risk, which restricts the ability to increase the radiation dose adequately for enhancing treatment effectiveness. This survey provides a comprehensive overview of…

Medical Physics · Physics 2023-07-27 Amir Moslemi , Navid Khaledi

Individualized treatment rules/recommendations (ITRs) aim to improve patient outcomes by tailoring treatments to the characteristics of each individual. However, when there are many treatment groups, existing methods face significant…

Methodology · Statistics 2025-05-27 Ke Zhu , Jianing Chu , Ilya Lipkovich , Wenyu Ye , Shu Yang

The complex heterogeneity of brain tumours is increasingly recognized to demand data of magnitudes and richness only fully-inclusive, large-scale collections drawn from routine clinical care could plausibly offer. This is a task…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 James K Ruffle , Samia Mohinta , Robert J Gray , Harpreet Hyare , Parashkev Nachev

Deep learning has facilitated the automation of radiotherapy by predicting accurate dose distribution maps. However, existing methods fail to derive the desirable radiotherapy parameters that can be directly input into the treatment…

Computer Vision and Pattern Recognition · Computer Science 2024-03-01 Jiaqi Cui , Yuanyuan Xu , Jianghong Xiao , Yuchen Fei , Jiliu Zhou , Xingcheng Peng , Yan Wang

This paper deals with the classic radiotherapy dose fractionation problem for cancer tumors concerning the following goals: a) To maximize the effect of radiation on the tumor, restricting the effect produced to the organs at risk (healing…

Optimization and Control · Mathematics 2021-02-17 Luis Alberto Fernández , Lucía Fernández

Radiation therapy is an important tool in the treatment of breast cancer and can play a crucial role in improving patient outcomes. For breast cancer, if the technique has been for a long time the use of 3DCRT, clinicians have seen the…

Purpose: Development of a novel interactive visualization approach for the exploration of radiotherapy treatment plans with a focus on overlap volumes with the aim of healthy tissue sparing. Methods: We propose a visualization approach to…

Human-Computer Interaction · Computer Science 2023-10-03 Matthias Schlachter , Samuel Peters , Daniel Camenisch , Paul Martin Putora , Katja Bühler

Radiation Therapy (RT) plays a pivotal role in the treatment of cancer, offering the potential to effectively target and eliminate tumour cells while minimizing harm to surrounding healthy tissues. However, the success of RT heavily depends…

Medical Physics · Physics 2024-02-16 Keshav Kumar K. , NVSL Narasimham , A. Ramakrishna Prasad

Manual brain tumor segmentation from MRI scans is challenging due to tumor heterogeneity, scarcity of annotated data, and class imbalance in medical imaging datasets. Synthetic data generated by generative models has the potential to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Aditi Jahagirdar , Sameer Joshi

To our knowledge, all deep computer-aided detection and diagnosis (CAD) systems for prostate cancer (PCa) detection consider bi-parametric magnetic resonance imaging (bp-MRI) only, including T2w and ADC sequences while excluding the 4D…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Audrey Duran , Gaspard Dussert , Carole Lartizien

Radiotherapy is one of the primary treatment methods for tumors, but the organ movement caused by respiration limits its accuracy. Recently, 3D imaging from a single X-ray projection has received extensive attention as a promising approach…

Image and Video Processing · Electrical Eng. & Systems 2024-04-01 Miao Zhu , Qiming Fu , Bo Liu , Mengxi Zhang , Bojian Li , Xiaoyan Luo , Fugen Zhou

Radiotherapy aims to deliver a prescribed dose to the tumor while sparing neighboring organs at risk (OARs). Increasingly complex treatment techniques such as volumetric modulated arc therapy (VMAT), stereotactic radiosurgery (SRS),…

Medical Physics · Physics 2023-10-23 Elahheh Salari , Jing Wang , Jacob Wynne , Chih-Wei Chang , Xiaofeng Yang
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