English
Related papers

Related papers: Constructing Bio-molecular Databases on a DNA-base…

200 papers

DNA-based storage offers unprecedented density and durability, but its scalability is fundamentally limited by the efficiency of parallel strand synthesis. Existing methods either allow unconstrained nucleotide additions to individual…

Information Theory · Computer Science 2025-10-27 Boaz Moav , Ryan Gabrys , Eitan Yaakobi

A coreset is a small set that can approximately preserve the structure of the original input data set. Therefore we can run our algorithm on a coreset so as to reduce the total computational complexity. Conventional coreset techniques…

Machine Learning · Computer Science 2022-10-11 Jiaxiang Chen , Qingyuan Yang , Ruomin Huang , Hu Ding

A fundamental design rule that nature has developed for biological machines is the intimate correlation between motion and function. One class of biological machines is molecular motors in living cells, which directly convert chemical…

Biological Physics · Physics 2021-05-11 Na Liu

As the global need for large-scale data storage is rising exponentially, existing storage technologies are approaching their theoretical and functional limits in terms of density and energy consumption, making DNA based storage a potential…

Emerging Technologies · Computer Science 2021-10-12 Yotam Nahum , Eyar Ben-Tolila , Leon Anavy

Boltzmann machines are energy-based models that have been shown to provide an accurate statistical description of domains of evolutionary-related protein and RNA families. They are parametrized in terms of local biases accounting for…

Quantitative Methods · Quantitative Biology 2021-11-03 Anna Paola Muntoni , Andrea Pagnani , Martin Weigt , Francesco Zamponi

This paper presents a Bayesian method for constructing Bayesian belief networks from a database of cases. Potential applications include computer-assisted hypothesis testing, automated scientific discovery, and automated construction of…

Artificial Intelligence · Computer Science 2013-03-26 Gregory F. Cooper , Edward H. Herskovits

Efficiently solving NP-complete problems-such as protein structure prediction, cryptographic decryption, and vulnerability detection-remains a central challenge in computer science. Traditional electronic computers, constrained by the…

Data Structures and Algorithms · Computer Science 2025-07-18 Jin Xu , XiaoLong Shi , Xin Chen , Fang Wang , Sirui Li , Pali Ye , Boliang Zhang , Di Deng , Zheng Kou , Xiaoli Qiang

Data mining is a recognized predictive tool in a variety of areas ranging from bioinformatics and drug design to crystal structure prediction. In the present study, an electronic structure implementation has been combined with structural…

Materials Science · Physics 2008-08-18 C. Ortiz , O. Eriksson , M. Klintenberg

One of the distinctive features of Information Retrieval systems comparing to Database Management systems, is that they offer better compression for posting lists, resulting in better I/O performance and thus faster query evaluation. In…

Information Retrieval · Computer Science 2009-06-18 Panagiotis Papadakos , Yannis Theoharis , Yannis Marketakis , Nikos Armenatzoglou , Yannis Tzitzikas

DNA strands serve as a storage medium for $4$-ary data over the alphabet $\{A,T,G,C\}$. DNA data storage promises formidable information density, long-term durability, and ease of replicability. However, information in this intriguing…

Information Theory · Computer Science 2024-08-06 Canberk İrimağzı , Yusuf Uslan , Ahmed Hareedy

Cryptography is the science that secures data and communication over the network by applying mathematics and logic to design strong encryption methods. In the modern era of e-business and e-commerce the protection of confidentiality,…

Cryptography and Security · Computer Science 2023-08-07 Mandrita Mondal , Kumar S. Ray

Analytical database systems are typically designed to use a column-first data layout to access only the desired fields. On the other hand, storing data row-first works great for accessing, inserting, or updating entire rows. Transforming…

We propose the chemlambda artificial chemistry, whose behavior strongly suggests that real molecules which embed Interaction Nets patterns and real chemical reactions which resemble Interaction Nets graph rewrites could be a realistic path…

Emerging Technologies · Computer Science 2018-11-14 Marius Buliga

Optimizing the physical data storage and retrieval of data are two key database management problems. In this paper, we propose a language that can express a wide range of physical database layouts, going well beyond the row- and…

Programming Languages · Computer Science 2020-02-07 John K. Feser , Samuel Madden , Nan Tang , Armando Solar-Lezama

The vast amount of biological knowledge accumulated over the years has allowed researchers to identify various biochemical interactions and define different families of pathways. There is an increased interest in identifying pathways and…

Applications · Statistics 2011-11-24 Francesco C. Stingo , Yian A. Chen , Mahlet G. Tadesse , Marina Vannucci

The genetic information that dictates the structure and function of all life forms is encoded in the DNA. In 1953, Watson and Crick first presented the double helical structure of a DNA molecule. Their findings unearthed the desire to…

Genomics · Quantitative Biology 2023-05-16 Olaitan Akintunde , Trichina Tucker , Valerie J. Carabetta

Deep neural networks have been successfully deployed in a wide variety of applications including computer vision and speech recognition. However, computational and storage complexity of these models has forced the majority of computations…

Machine Learning · Computer Science 2018-08-28 Mahdi Nazemi , Ghasem Pasandi , Massoud Pedram

Database system architectures are undergoing revolutionary changes. Algorithms and data are being unified by integrating programming languages with the database system. This gives an extensible object-relational system where non-procedural…

Databases · Computer Science 2007-05-23 Jim Gray

This work addresses the inverse identification of apparent elastic properties of random heterogeneous materials using machine learning based on artificial neural networks. The proposed neural network-based identification method requires the…

Machine Learning · Computer Science 2021-02-12 Florent Pled , Christophe Desceliers , Tianyu Zhang

Bayesian network classifiers provide a feasible solution to tabular data classification, with a number of merits like high time and memory efficiency, and great explainability. However, due to the parameter explosion and data sparsity…

Machine Learning · Computer Science 2025-08-18 Huan Zhang , Daokun Zhang , Kexin Meng , Geoffrey I. Webb