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Branched molecules of deoxyribonucleic acid (DNA) can self-assemble into nanostructures through complementary cohesive strand base pairing. The production of DNA nanostructures is valuable in targeted drug delivery and biomolecular…

Combinatorics · Mathematics 2022-03-15 D. Chloe Griffin , Jessica Sorrells

This work introduces a number of algebraic topology approaches, such as multicomponent persistent homology, multi-level persistent homology and electrostatic persistence for the representation, characterization, and description of small…

Quantitative Methods · Quantitative Biology 2018-02-07 Zixuan Cang , Lin Mu , Guowei Wei

The rapid advance of DNA sequencing technologies has yielded databases of thousands of genomes. To search and index these databases effectively, it is important that we take advantage of the similarity between those genomes. Several authors…

Data Structures and Algorithms · Computer Science 2014-12-05 Travis Gagie , Simon J. Puglisi

Stochastic processes that involve the creation of objects and relations over time are widespread, but relatively poorly studied. For example, accurate fault diagnosis in factory assembly processes requires inferring the probabilities of…

Artificial Intelligence · Computer Science 2011-09-13 P. Domingos , S. Sanghai , D. Weld

Molecular motor proteins form the basis of cellular dynamics. Recently, notable efforts have led to the creation of their DNA-based mimics, which can carry out complex nanoscale motion. However, such functional analogues have not yet been…

Biological Physics · Physics 2021-05-14 Kerstin Goepfrich , Maximilian J. Urban , Christoph Frey , Ilia Platzman , Joachim P. Spatz , Na Liu

Deep Learning (DL) algorithms hold great promise for applications in the field of computational biophysics. In fact, the vast amount of available molecular structures, as well as their notable complexity, constitutes an ideal context in…

Soft Condensed Matter · Physics 2019-01-07 Marco Giulini , Raffaello Potestio

DNA data storage offers a high-density, long-term alternative to traditional storage systems, addressing the exponential growth of digital data. Composite DNA extends this paradigm by leveraging mixtures of nucleotides to increase storage…

Information Theory · Computer Science 2026-02-13 Busra Tegin , Tolga M Duman

Due to the highly complex chemical structure of biomolecules, the extensive understanding of the electronic information for proteomics can be challenging. Here, we constructed a charge transfer database at residue level derived from…

Chemical Physics · Physics 2019-04-05 Fang Liu , Hongwei Wang , Dongju Zhang , Likai Du

DNA, with remarkable properties of high density, durability, and replicability, is one of the most appealing storage media. Emerging DNA storage technologies use composite DNA letters, where information is represented by probability…

Information Theory · Computer Science 2025-03-26 Wenkai Zhang , Zhiying Wang

Deep neural network (DNN) and its variants have been extensively used for a wide spectrum of real applications such as image classification, face/speech recognition, fraud detection, and so on. In addition to many important machine learning…

Databases · Computer Science 2023-01-24 Xiang Lian , Xiaofei Zhang

With the rapid increase of available digital data, DNA storage is identified as a storage media with high density and capability of long-term preservation, especially for archival storage systems. However, the encoding density (i.e., how…

Emerging Technologies · Computer Science 2021-08-26 Bingzhe Li , Li Ou , David Du

DNA and other biopolymers are being investigated as new computing substrates and alternative to silicon-based digital computers. However, the established top-down design of biomolecular interaction networks remains challenging and does not…

Soft Condensed Matter · Physics 2025-11-19 Tanmay Pandey , Petro Feketa , Jan Steinkühler

DNA storage is a promising archival data storage solution to today's big data problem. A DNA storage system encodes and stores digital data with synthetic DNA sequences and decodes DNA sequences back to digital data via sequencing. For…

Emerging Technologies · Computer Science 2024-03-22 Yixun Wei , Wenlong Wang , Huibing Dong , Bingzhe Li , David Du

Biologists are increasingly using databases for storing and managing their data. Biological databases typically consist of a mixture of raw data, metadata, sequences, annotations, and related data obtained from various sources. Current…

Databases · Computer Science 2007-05-23 Mohamed Y. Eltabakh , Mourad Ouzzani , Walid G. Aref

In this paper, we study achievable rates of concatenated coding schemes over a deoxyribonucleic acid (DNA) storage channel. Our channel model incorporates the main features of DNA-based data storage. First, information is stored on many,…

Information Theory · Computer Science 2020-05-04 Andreas Lenz , Lorenz Welter , Sven Puchinger

High-throughput computational materials design promises to greatly accelerate the process of discovering new materials and compounds, and of optimizing their properties. The large databases of structures and properties that result from…

Chemical Physics · Physics 2016-11-22 Sandip De , Felix Musil , Teresa Ingram , Carsten Baldauf , Michele Ceriotti

The DNA cryptography is a new and very promising direction in cryptography research. DNA can be used in cryptography for storing and transmitting the information, as well as for computation. Although in its primitive stage, DNA cryptography…

Cryptography and Security · Computer Science 2012-03-07 Kang Ning

The multi relational data mining approach has developed as an alternative way for handling the structured data such that RDBMS. This will provides the mining in multiple tables directly. In MRDM the patterns are available in multiple tables…

Databases · Computer Science 2012-11-19 Neelamadhab Padhy , Rasmita Panigrahi

The overwhelming amount of available scholarly literature in the life sciences poses significant challenges to scientists wishing to keep up with important developments related to their research, but also provides a useful resource for the…

Quantitative Methods · Quantitative Biology 2011-03-29 Huijun Wang , Ying Ding , Jie Tang , Xiao Dong , Bing He , Judy Qiu , David J. Wild

Genetic information is stored in a linear sequence of base-pairs; however, thermal fluctuations and complex DNA conformations such as folds and loops make it challenging to order genomic material for in vitro analysis. In this work, we…