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Genotype networks are a method used in systems biology to study the "innovability" of a set of genotypes having the same phenotype. In the past they have been applied to determine the genetic heterogeneity, and stability to mutations, of…

Populations and Evolution · Quantitative Biology 2015-06-17 Giovanni Marco Dall'Olio , Jaume Bertranpetit , Andreas Wagner , Hafid Laayouni

Social choice theory is the study of preference aggregation across a population, used both in mechanism design for human agents and in the democratic alignment of language models. In this study, we propose the representative social choice…

Machine Learning · Computer Science 2025-11-03 Tianyi Qiu

Real-world complex systems are often better modeled as hypergraphs, where edges represent group interactions involving multiple entities. Understanding and quantifying homophily (similarity-driven association) in such networks is essential…

Social and Information Networks · Computer Science 2025-11-25 Gaurav Kumar , Akrati Saxena , Chandrakala Meena

Understanding genetic variation, e.g., through mutations, in organisms is crucial to unravel their effects on the environment and human health. A fundamental characterization can be obtained by solving the haplotype assembly problem, which…

Genomics · Quantitative Biology 2022-10-25 Hansheng Xue , Vaibhav Rajan , Yu Lin

We introduce a general modeling framework to predict the outcomes, at the population level, of individual psychology and behavior. The framework prescribes that researchers build a cost function that embodies knowledge of what trait values…

Physics and Society · Physics 2007-05-23 Pierluigi Contucci , Stefano Ghirlanda

One property of networks that has received comparatively little attention is hierarchy, i.e., the property of having vertices that cluster together in groups, which then join to form groups of groups, and so forth, up through all levels of…

Physics and Society · Physics 2008-04-12 Aaron Clauset , Cristopher Moore , M. E. J. Newman

In the last few years we have witnessed the emergence, primarily in on-line communities, of new types of social networks that require for their representation more complex graph structures than have been employed in the past. One example is…

Physics and Society · Physics 2009-08-13 Gourab Ghoshal , Vinko Zlatic , Guido Caldarelli , M. E. J. Newman

Compartmental models are valuable tools for investigating infectious diseases. Researchers building such models typically begin with a simple structure where compartments correspond to individuals with different epidemiological statuses,…

Populations and Evolution · Quantitative Biology 2023-07-21 Darren Flynn-Primrose , Steven C. Walker , Michael Li , Benjamin M. Bolker , David J. D. Earn , Jonathan Dushoff

Graph is a universe data structure that is widely used to organize data in real-world. Various real-word networks like the transportation network, social and academic network can be represented by graphs. Recent years have witnessed the…

Machine Learning · Computer Science 2021-11-23 Xueyi Liu , Jie Tang

We describe a continuous-time modelling framework for biological population dynamics that accounts for demographic noise. In the spirit of the methodology used by statistical physicists, transitions between the states of the system are…

Populations and Evolution · Quantitative Biology 2018-07-19 George W. A. Constable , Alan J. McKane

This paper focuses on two fundamental tasks of graph analysis: community detection and node representation learning, which capture the global and local structures of graphs, respectively. In the current literature, these two tasks are…

Social and Information Networks · Computer Science 2019-09-18 Fan-Yun Sun , Meng Qu , Jordan Hoffmann , Chin-Wei Huang , Jian Tang

Temporal social networks of human interactions are preponderant in understanding the fundamental patterns of human behavior. In these networks, interactions occur locally between individuals (i.e., nodes) who connect with each other at…

Physics and Society · Physics 2022-10-11 Shaunette T. Ferguson , Teruyoshi Kobayashi

Despite the remarkable success of large large-scale neural networks, we still lack unified notation for thinking about and describing their representational spaces. We lack methods to reliably describe how their representations are…

Machine Learning · Computer Science 2025-06-02 Henry Conklin

Modeling higher-order interactions (HOI) has emerged as a crucial challenge in complex systems analysis, as many phenomena cannot be fully captured by pairwise relationships alone. Hypergraphs, which generalize graphs by allowing…

Applications · Statistics 2026-03-31 Catherine Matias

The progression of a cell population where each individual is characterized by the value of an internal variable varying with time (e.g. size, weight, and protein concentration) is typically modeled by a Population Balance Equation, a first…

Cell Behavior · Quantitative Biology 2016-04-20 Qasim Ali , Ali Elkamel , Frédéric Gruy , Claude Lambert , Eric Touboul

Over the past decade, deep neural networks have proven to be adept in image classification tasks, often surpassing humans in terms of accuracy. However, standard neural networks often fail to understand the concept of hierarchical…

Computer Vision and Pattern Recognition · Computer Science 2022-06-15 Amitangshu Mukherjee , Isha Garg , Kaushik Roy

Large-scale human social network structure is typically inferred from digital trace samples of online social media platforms or mobile communication data. Instead, here we investigate the social network structure of a complete population,…

Physics and Society · Physics 2022-11-29 Eszter Bokányi , Eelke M. Heemskerk , Frank W. Takes

Graph sparsification is a powerful tool to approximate an arbitrary graph and has been used in machine learning over homogeneous graphs. In heterogeneous graphs such as knowledge graphs, however, sparsification has not been systematically…

Machine Learning · Computer Science 2022-11-15 Chandan Chunduru , Chun Jiang Zhu , Blake Gains , Jinbo Bi

It is basic question in biology and other fields to identify the char- acteristic properties that on one hand are shared by structures from a particular realm, like gene regulation, protein-protein interaction or neu- ral networks or…

Quantitative Methods · Quantitative Biology 2012-10-19 Anirban Banerjee , Jürgen Jost

The increasing prevalence of relational data describing interactions among a target population has motivated a wide literature on statistical network analysis. In many applications, interactions may involve more than two members of the…

Methodology · Statistics 2021-11-03 Kathryn Turnbull , Simón Lunagómez , Christopher Nemeth , Edoardo Airoldi