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Contractile actomyosin network flows are crucial for many cellular processes including cell division and motility, morphogenesis and transport. How local remodeling of actin architecture tunes stress production and dissipation and regulates…

We introduce a minimalistic model based on dynamic node deletion and node duplication with heterodimerisation. The model is intended to capture the essential features of the evolution of protein interaction networks. We derive an exact…

Biological Physics · Physics 2009-11-13 Nadia Farid , Kim Christensen

Reciprocity, or the stochastic tendency for actors to form mutual relationships, is an essential characteristic of directed network data. Existing latent space approaches to modeling directed networks are severely limited by the assumption…

Methodology · Statistics 2024-11-28 Joshua Daniel Loyal , Xiangyu Wu , Jonathan R. Stewart

Cytoskeletons are self-organized networks based on polymerized proteins: actin, tubulin, and driven by motor proteins, such as myosin, kinesin and dynein. Their positive Darwinian evolution enables them to approach optimized functionality…

Other Quantitative Biology · Quantitative Biology 2020-11-04 J. C. Phillips

Proteins in photosynthetic membranes can organize into patterned arrays that span the membrane's lateral size. Attractions between proteins in different layers of a membrane stack can play a key role in this ordering, as was suggested by…

Soft Condensed Matter · Physics 2020-09-09 Andreana M. Rosnik , Phillip L. Geissler

Cells and tissues exert forces and can actively change shape. This strikingly autonomous behavior is powered by the cytoskeleton, which includes an active gel of actin filaments, crosslinks, and myosin molecular motors. Although individual…

Soft Condensed Matter · Physics 2017-07-26 José Alvarado , Misha Sheinman , Abhinav Sharma , Fred C. MacKintosh , Gijsje H. Koenderink

Complex networks are a powerful modeling tool, allowing the study of countless real-world systems. They have been used in very different domains such as computer science, biology, sociology, management, etc. Authors have been trying to…

Social and Information Networks · Computer Science 2014-02-04 Burcu Kantarcı , Vincent Labatut

Degree distribution of nodes, especially a power law degree distribution, has been regarded as one of the most significant structural characteristics of social and information networks. Node degree, however, only discloses the first-order…

Social and Information Networks · Computer Science 2010-09-23 Ajay Sridharan , Yong Gao , Kui Wu , James Nastos

Brain can be represented as a network, where regions are the nodes and relations between the regions are edges. Within a network, co-existence of cooperative and competitive relationships between different nodes is called coopetition.…

Neurons and Cognition · Quantitative Biology 2018-02-13 Subhadip Paul , Satyam Mukherjee , Sagnik Bhattacharyya

There is a rich history of models for the interaction of a biological contagion like influenza with the spread of related information such as an influenza vaccination campaign. Recent work on the spread of interacting contagions on networks…

Physics and Society · Physics 2020-09-02 Laurent Hébert-Dufresne , Dina Mistry , Benjamin M. Althouse

Cooperation is a fundamental social mechanism, whose effects on human performance have been investigated in several environments. Online games are modern-days natural settings in which cooperation strongly affects human behavior. Every day,…

Social and Information Networks · Computer Science 2019-08-22 Anna Sapienza , Palash Goyal , Emilio Ferrara

We address the problem of message transfer in a communication network. The network consists of nodes and links, with the nodes lying on a two dimensional lattice. Each node has connections with its nearest neighbours, whereas some special…

Statistical Mechanics · Physics 2007-05-23 Brajendra K. Singh , Neelima M. Gupte

Temporal-network models have provided key insights into how time-varying connectivity shapes dynamical processes such as spreading. Among them, the activity-driven model is a widely used, analytically tractable benchmark. Yet many temporal…

Physics and Society · Physics 2025-11-20 Zsófia Simon , Jari Saramäki

We present a method that compares the protein interaction networks of two species to detect functionally similar (conserved) protein modules between them. The method is based on an algorithm we developed to identify matching subgraphs…

Molecular Networks · Quantitative Biology 2007-05-23 Manikandan Narayanan , Richard M. Karp

In the study of biological networks, one of the major challenges is to understand the relationships between network structure and dynamics. In this paper, we model in vitro cortical neuronal cultures as stochastic dynamical systems and…

Neurons and Cognition · Quantitative Biology 2022-05-04 Chumin Sun , K. C. Lin , C. Y. Yeung , Emily S. C. Ching , Yu-Ting Huang , Pik-Yin Lai , C. K. Chan

We test the claim by Yu et al. -- presented in Science 322, 104 (2008) -- that the degree distribution of the yeast (Saccharomyces cerevisiae) protein-interaction network is best approximated by a power law. Yu et al. consider three…

Molecular Networks · Quantitative Biology 2009-01-06 Aaron Clauset

The rapidly developing theory of complex networks indicates that real networks are not random, but have a highly robust large-scale architecture, governed by strict organizational principles. Here, we focus on the properties of biological…

Molecular Networks · Quantitative Biology 2007-05-23 E. Almaas , A. -L. Barabasi

Motivation: With the aim to amplify and make sense of interactions of virus-human proteins in the case of SARS-CoV-2, we performed a structural analysis of the network of protein interactions obtained from the integration of three sources:…

Molecular Networks · Quantitative Biology 2020-09-15 Beatriz Luna , Marcelino Ramírez , Edgardo Galán

There are diverse mechanisms driving the evolution of social networks. A key open question dealing with understanding their evolution is: How various preferential linking mechanisms produce networks with different features? In this paper we…

Physics and Society · Physics 2015-06-12 Haibo Hu , Jinli Guo , Xuan Liu

The similarity between neural and immune networks has been known for decades, but so far we did not understand the mechanism that allows the immune system, unlike associative neural networks, to recall and execute a large number of…

Disordered Systems and Neural Networks · Physics 2017-03-20 Elena Agliari , Alessia Annibale , Adriano Barra , A. C. C. Coolen , Daniele Tantari