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Related papers: An Empirical Study of Immune System Based On Bipar…

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Immune cells coordinate their efforts for the correct and efficient functioning of the immune system (IS). Each cell type plays a distinct role and communicates with other cell types through mediators such as cytokines, chemokines and…

Molecular Networks · Quantitative Biology 2007-05-23 Paolo Tieri , Silvana Valensin , Vito Latora , Gastone C. Castellani , Massimo Marchiori , Daniel Remondini , Claudio Franceschi

In this paper, we present the empirical investigation results on the neuroendocrine system by bipartite graphs. This neuroendocrine network model can describe the structural characteristic of neuroendocrine system. The act degree…

Adaptation and Self-Organizing Systems · Physics 2007-12-04 Sheng-Rong Zou , Zhong-Wei Guo , Yu-Jing Peng , Ta Zhou , Chang-Gui Gu , Da-Ren He

We argue that immune system is an adaptive complex system. It is shown that it has emergent properties. Its network structure is of the small world network type. The network is of the threshold type, which helps in avoiding autoimmunity. It…

Populations and Evolution · Quantitative Biology 2008-01-08 E. Ahmed , A. H. Hashish

The similarity between neural and immune networks has been known for decades, but so far we did not understand the mechanism that allows the immune system, unlike associative neural networks, to recall and execute a large number of…

Disordered Systems and Neural Networks · Physics 2017-03-20 Elena Agliari , Alessia Annibale , Adriano Barra , A. C. C. Coolen , Daniele Tantari

Complex networks provide us a new view for investigation of immune systems. In this paper we collect data through STRING database and present a model with cooperation network theory. The cytokine-protein network model we consider is…

Adaptation and Self-Organizing Systems · Physics 2007-12-06 Sheng-Rong Zou , Ta Zhou , Yu-Jing Peng , Zhong-Wei Guo , Chang-gui Gu , Da-Ren He

Pattern-diluted associative networks were introduced recently as models for the immune system, with nodes representing T-lymphocytes and stored patterns representing signalling protocols between T- and B-lymphocytes. It was shown earlier…

Disordered Systems and Neural Networks · Physics 2015-04-17 Elena Agliari , Alessia Annibale , Adriano Barra , A. C. C. Coolen , Daniele Tantari

The biological immune system is a robust, complex, adaptive system that defends the body from foreign pathogens. It is able to categorize all cells (or molecules) within the body as self-cells or non-self cells. It does this with the help…

Artificial Intelligence · Computer Science 2010-07-05 Uwe Aickelin , Dipankar Dasgupta

Associative network models featuring multi-tasking properties have been introduced recently and studied in the low load regime, where the number $P$ of simultaneously retrievable patterns scales with the number $N$ of nodes as $P\sim \log…

Disordered Systems and Neural Networks · Physics 2013-03-01 Elena Agliari , Alessia Annibale , Adriano Barra , A. C. C. Coolen , Daniele Tantari

The immune system can be thought as a complex network of different interacting elements. A cellular automaton, defined in shape-space, was recently shown to exhibit self-regulation and complex behavior and is, therefore, a good candidate to…

Statistical Mechanics · Physics 2009-10-31 Rita Maria Zorzenon dos Santos , Americo T. Bernardes

The biological immune system is a robust, complex, adaptive system that defends the body from foreign pathogens. It is able to categorize all cells (or molecules) within the body as self-cells or non-self cells. It does this with the help…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin , Dipankar Dasgupta

Understanding and modelling the complexity of the immune system is a challenge that is shared by the ImmunoComplexiT$^1$ thematic network from the RNSC. The immune system is a complex biological, adaptive, highly diversified, self-organized…

Quantitative Methods · Quantitative Biology 2020-08-27 Véronique Thomas-Vaslin

The biological immune system is a robust, complex, adaptive system that defends the body from foreign pathogens. It is able to categorize all cells (or molecules) within the body as self or non-self substances. It does this with the help of…

Neural and Evolutionary Computing · Computer Science 2013-08-26 Uwe Aickelin , Dipankar Dasgupta , Feng Gu

In this work we adopt a statistical mechanics approach to investigate basic, systemic features exhibited by adaptive immune systems. The lymphocyte network made by B-cells and T-cells is modeled by a bipartite spin-glass, where, following…

Cell Behavior · Quantitative Biology 2015-06-04 Elena Agliari , Adriano Barra , Silvia Bartolucci , Andrea Galluzzi , Francesco Guerra , Francesco Moauro

The human body has a very effective Immune system used to protect the body from dangerous foreign pathogens. This paper aims at studying the immunology and understanding how it works, it also shaded light on the usage of the immunology…

Networking and Internet Architecture · Computer Science 2017-07-25 Almotasem Bellah Alajlouni

Some years ago a cellular automata model was proposed to describe the evolution of the immune repertoire of B cells and antibodies based on Jerne's immune network theory and shape-space formalism. Here we investigate if the networks…

Biological Physics · Physics 2012-01-31 Hallan Souza-e-Silva , Rita Maria Zorzenon dos Santos

Cells of the immune system are confronted with opposing pro- and anti-inflammatory signals. Dendritic cells (DC) integrate these cues to make informed decisions whether to initiate an immune response. Confronted with exogenous microbial…

Molecular Networks · Quantitative Biology 2020-11-20 Quentin Marcou , Irit Carmi-Levy , Coline Trichot , Vassili Soumelis , Thierry Mora , Aleksandra M. Walczak

We consider the mutual interactions, via cytokine exchanges, among helper lymphocytes, B lymphocytes and killer lymphocytes, and we model them as a unique system by means of a tripartite network. Each part includes all the different clones…

Biological Physics · Physics 2015-03-19 Elena Agliari , Adriano Barra , Francesco Guerra , Francesco Moauro

Among the diverse and important applications that networks currently have is the modeling of infectious diseases. Immunization, or the process of protecting nodes in the network, plays a key role in stopping diseases from spreading. Hence…

Populations and Evolution · Quantitative Biology 2021-07-22 Ronald Manríquez , Camilo Guerrero-Nancuante

We introduce a 2-layer network model for the study of the immunization dynamics in epidemics. Spreading of an epidemic is modeled as an excitatory process in a small-world network (body layer) while immunization by prevention for the…

Disordered Systems and Neural Networks · Physics 2007-05-23 Hang-Hyun Jo , Hie-Tae Moon , Seung Ki Baek

The coming 5G networks have been enabling the creation of a wide variety of new services and applications which demand a new network security architecture. Immunology is the study of the immune system in vertebrates (including humans) which…

Cryptography and Security · Computer Science 2020-01-28 Quan Yu , Jing Ren , Jiyan Zhang , Siyang Liu , Yinjin Fu , Ying Li , Linru Ma , Jian Jing , Wei Zhang
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