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Related papers: Screening-Limited Response of NanoBiosensors

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Probing optical excitations with nanometer resolution is important for understanding their dynamics and interactions down to the atomic scale. Electron microscopes currently offer the unparalleled ability of rendering spatially-resolved…

Quantum Physics · Physics 2020-07-16 Valerio Di Giulio , Mathieu Kociak , F. Javier García de Abajo

The collective response of metal nanostructures to optical excitation leads to localized plasmon generation with nanoscale field confinement driving applications in e.g. quantum optics, optoelectronics, and nanophotonics, where a bottleneck…

Silicon nanochannel biological field effect transistors have been developed for glucose detection. The device is nanofabricated from a silicon-on-insulator wafer with a top-down approach and surface functionalized with glucose oxidase. The…

Biological Physics · Physics 2008-02-14 Xihua Wang , Yu Chen , Katherine A. Gibney , Shyamsunder Erramilli , Pritiraj Mohanty

Understanding the dynamics of electrical signals within neuronal assemblies is crucial to unraveling complex brain function. Despite recent advances in employing optically active nanostructures in transmembrane potential sensing, there…

Interactions between surfaces and proteins occur in many vital processes and are crucial in biotechnology: the ability to control specific interactions is essential in fields like biomaterials, biomedical implants and biosensors. In the…

Computational Physics · Physics 2016-04-20 Christopher D. Cooper , Lorena A. Barba

Electron microscopy (EM) has been instrumental in our understanding of biological systems ranging from subcellular structures to complex organisms. Although EM reveals cellular morphology with nanoscale resolution, it does not provide…

Using molecular dynamics simulations, we reveal emergent properties of hydrated electrode interfaces that while molecular in origin are integral to the behavior of the system across long times scales and large length scales. Specifically,…

Materials Science · Physics 2015-05-20 David T. Limmer , Adam P. Willard

In the biochemical sensing field, a fervent research activity related to the development of real time, low cost, compact and high throughput devices for the detection and characterization of natural or synthetic nanoparticles NPs actually…

Optics · Physics 2014-01-13 Clarissa Martina Campanella

Biomolecules exhibit dynamic conformations critical to their functions, yet observing these processes at the single-molecule level under native conditions remains a formidable challenge. While surface immobilization has been widely used to…

Instrumentation and Detectors · Physics 2025-12-22 Funing Liu , Qitao Hu , Anton Sabantsev , Giovanni Di Muccio , Shuangshuang Zeng , Mauro Chinappi , Sebastian Deindl , Zhen Zhang

Understanding the behavior of biomolecules such as proteins requires understanding the critical influence of the surrounding fluid (solvent) environment--water with mobile salt ions such as sodium. Unfortunately, for many studies, fully…

Soft Condensed Matter · Physics 2015-05-27 J. P. Bardhan , D. A. Tejani , N. S. Wieckowski , A. Ramaswamy , M. G. Knepley

We describe two different modes for electronically detecting an adsorbed molecule using a nanoscale transistor. The attachment of an ionic molecular target shifts the threshold voltage through modulation of the depletion layer…

Mesoscale and Nanoscale Physics · Physics 2008-08-19 S. Vasudevan , K. Walczak , N. Kapur , M. Neurock , A. W. Ghosh

Plasmonic metal nanostructures are an integral part of nanophotonic device applications owing to their ability to generate strong localized electromagnetic fields when illuminated from the far-field. These nanostructures can be prepared in…

Mesoscale and Nanoscale Physics · Physics 2018-02-05 Sunil Kumar , A. K. Sood

The characterization of individual nanoparticles in a liquid constitutes a critical challenge for environmental, material, and biological sciences. To detect nanoparticles, electronic approaches are especially desirable owing to their…

Within a dipolar Poisson-Boltzmann theory including electrostatic correlations, we consider the effect of explicit solvent structure on solvent and ion partition confined to charged nanopores. We develop a relaxation scheme for the solution…

Soft Condensed Matter · Physics 2015-10-28 Sahin Buyukdagli

Graphene based nanomaterials have attracted significant attention for their potentials in biomedical and biotechnology applications in recent years, owing to the outstanding physical and chemical properties. However, the interaction…

Biomolecules · Quantitative Biology 2024-04-09 Jing Ye , Minzhi Fan , Xiaoyu Zhang , Shasha Lu , Mengyao Chai , Yunshan Zhang , Xiaoyu Zhao , Shuang Li , Diming Zhang

Nanowire field-effect sensors have recently been developed for label-free detection of biomolecules. In this work, we introduce a computational technique based on Bayesian estimation to determine the physical parameters of the sensor and,…

Numerical Analysis · Mathematics 2019-10-29 Amirreza Khodadadian , Benjamin Stadlbauer , Clemens Heitzinger

Electrochemical techniques conventionally lack spatial resolution and average local information over an entire electrode. While advancements in spatial resolution have been made through scanning probe methods, monitoring dynamics over large…

Mesoscale and Nanoscale Physics · Physics 2024-05-20 Eveline Mayner , Nathan Ronceray , Martina Lihter , Tzu-Heng Chen , Kenji Watanabe , Takashi Taniguchi , Aleksandra Radenovic

We report a novel behavior of the surface plasmon linewidth in sodium nanospheres Na$_{1760}$ changing with the electron temperature, which monotonically decreases and bears a discontinuous sudden drop at high electron temperatures. Our…

Mesoscale and Nanoscale Physics · Physics 2014-08-15 Guozhong Wang , Yizhuang Zheng , Jian Zi

This article presents a new class of batch-fabricated, low-power and highly sensitive chemiresistive sensors. We first present the design, fabrication and characterization of batch-fabricated sidewall etched vertical nanogap…

Applied Physics · Physics 2020-06-24 Aishwaryadev Banerjee

Local electrochemical measurements and imaging at the nanoscale are crucial for the future development of molecular devices, sensors, materials engineering, electrophysiology and various energy applications from artificial photosynthesis to…