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A wide range of synthesized crystalline inorganic materials exhibit compositional disorder, where multiple atomic species partially occupy the same crystallographic site. As a result, the physical and chemical properties of such materials…

DNA nanotechnology allows for the realization of complex nanoarchitectures in which the spatial arrangements of different constituents and most functions can be enabled by DNA. When optically active components are integrated in such…

Biological Physics · Physics 2021-05-10 Pengfei Zhan , Steffen Both , Thomas Weiss , Na Liu

We present a numerical analysis of a DNA hydrogel that consists of three-valent Y-shaped DNA molecules. The building blocks self-assemble fully reversibly from complementary single-stranded DNA segments. We compare melting curves from both…

Soft Condensed Matter · Physics 2019-04-04 Yair Augusto Gutierrez Fosado , Zhongyang Xing , Erika Eiser , Magdalena Hudek , Oliver Henrich

Crystal structure design is important for the discovery of new highly functional materials because crystal structure strongly influences material properties. Crystal structures are composed of space-filling polyhedra, which affect material…

Materials Science · Physics 2024-02-06 Tomoyasu Yokoyama , Kazuhide Ichikawa , Hisashi Naito

Structural DNA nanotechnology has advanced to the extent that extremely complex structures can be designed. Much of this advancement has been due to the development of automated DNA design and simulation tools. Typically, the tools (e.g.…

Biomolecules · Quantitative Biology 2021-12-01 Durham Smith , Grigory Tikhomirov

Multi-component aggregates are being intensively researched in various fields because of their highly tunable properties and wide applications. Due to the complex configurational space of these systems, research would greatly benefit from a…

Atomic and Molecular Clusters · Physics 2025-02-26 Nicolò Canestrari , Diana Nelli , Riccardo Ferrando

The collective behavior of the shortest DNA oligomers in high concentration aqueous solutions is an unexplored frontier of DNA science and technology. Here we broaden the realm of DNA nanoscience by demonstrating that single-component…

Materials Science · Physics 2024-03-13 Gregory P. Smith , Tommaso P. Fraccia , Chenhui Zhu , Tommaso Bellini , Noel A. Clark

DNA plays a special role in polymer science not just because of the highly selective recognition of complementary single DNA strands but also because bacteria can express DNA chains that are very long yet perfectly monodisperse. The latter…

Soft Condensed Matter · Physics 2009-06-18 Nienke Geerts , Erika Eiser

We present a modular DNA origami design approach to address the challenges of assembling geometrically complex nanoscale structures, including those with nonuniform Gaussian curvature. This approach features a core structure that completely…

In many organisms, homologous (or repetitive) chromosomal regions can associate or/and undergo concerted epigenetic changes in the absence of DNA breakage and recombination. The direct specific pairing of DNA duplexes with similar…

Biomolecules · Quantitative Biology 2022-10-26 Alexey K. Mazur , Eugene Gladyshev

We simulate the assembly of DNA copolymers from two types of short duplexes (short double strands with a single-stranded overhang at each end), as described by the oxDNA model. We find that the statistics of chain lengths can be well…

Soft Condensed Matter · Physics 2021-11-09 R. Foffi , F. Sciortino , J. M. Tavares , P. I. C. Teixeira

DNA nanotechnology uses predictable interactions of nucleic acids to precisely engineer complex nanostructures. Characterizing these self-assembled structures at the single-structure level is crucial for validating their design and…

Biological Physics · Physics 2025-10-21 Wangwei Dong , Zezhou Liu , Ruiyao Liu , Deborah Kuchnir Fygenson , Walter Reisner

The Kinetoplast DNA (kDNA) is a two-dimensional Olympic-ring-like network of mutually linked 2.5 kb-long DNA minicircles found in certain parasites called Trypanosomes. Understanding the self-assembly and replication of this structure are…

Soft Condensed Matter · Physics 2022-09-07 Pinyao He , Allard J. Katan , Luca Tubiana , Cees Dekker , Davide Michieletto

Molecular electronics and other technologies whose components comprise individual molecules have been pursued for half a century because the molecular scale represents the limit of miniaturisation of objects whose structure is tuneable for…

We report Monte Carlo simulations of a simple off-lattice patchy-particle model for DNA `bricks'. We relate the parameters that characterise this model with the binding free energy of pairs of single-stranded DNA molecules. We verify that…

Soft Condensed Matter · Physics 2016-07-21 Aleks Reinhardt , Daan Frenkel

In this paper, we consider the problem of designing DNA sequences (codewords) for DNA storage systems and DNA computing that are unlikely to fold back onto themselves to form undesirable secondary structures. The paper addresses both the…

Discrete Mathematics · Computer Science 2016-11-17 Olgica Milenkovic , Navin Kashyap

We study theoretically a binary system in which an attraction of unlike particles is combined with a type-independent soft core repulsion. The possible experimental implementation of the system is a mixture of DNA-covered colloids, in which…

Soft Condensed Matter · Physics 2007-05-23 Alexei V. Tkachenko

Cryptography is the science that secures data and communication over the network by applying mathematics and logic to design strong encryption methods. In the modern era of e-business and e-commerce the protection of confidentiality,…

Cryptography and Security · Computer Science 2023-08-07 Mandrita Mondal , Kumar S. Ray

Synthesis of tri functional electrically conducting, optical and magnetic nano-chain of Nicore-Aushell has been discussed here. Our Investigation indicates that such material attached with biomolecule DNA in chain form will have great…

Materials Science · Physics 2009-01-05 Madhuri Mandal , Kalyan Mandal

The field of complex self-assembly is moving toward the design of multi-particle structures consisting of thousands of distinct building blocks. To exploit the potential benefits of structures with such `addressable complexity,' we need to…

Soft Condensed Matter · Physics 2015-06-02 William M. Jacobs , Aleks Reinhardt , Daan Frenkel