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Related papers: The narrow escape problem revisited

200 papers

Kramer's theory of activation over a potential barrier consists in computing the mean exit time from the boundary of a basin of attraction of a randomly perturbed dynamical system. Here we report that for some systems, crossing the boundary…

Statistical Mechanics · Physics 2021-05-19 Lou Zonca , David Holcman

Questions of flux regulation in biological cells raise renewed interest in the narrow escape problem. The often inadequate expansions of the narrow escape time are due to a not so well known fact that the boundary singularity of Green's…

Mathematical Physics · Physics 2009-11-13 A. Singer , Z. Schuss , D. Holcman

This paper investigates a diffusion process in a narrow tubular domain with reflecting boundary conditions, where the geometry serves as a singular perturbation of an underlying graph in $\mathbb{R}^2$ or $\mathbb{R}^3$. The construction…

Probability · Mathematics 2025-09-04 Wen-Tai Hsu

Narrow escape and narrow capture problems which describe the average times required to stop the motion of a randomly travelling particle within a domain have applications in various areas of science. While for general domains, it is known…

Statistical Mechanics · Physics 2022-01-14 Jason Gilbert , Alexei Cheviakov

Certain biological reactions, such as receptor-ligand binding at cell-cell interfaces and macromolecules binding to biopolymers, require many smaller molecules crowding a reaction site to be cleared. Examples include the T cell interface, a…

Subcellular Processes · Quantitative Biology 2016-03-30 Jay Newby , Jun Allard

The function of many membrane-enclosed intracellular structures relies on release of diffusing particles that exit through narrow pores or channels in the membrane. The rate of release varies with pore size, density, and length of the…

Biological Physics · Physics 2023-02-08 Zitao Yang , Elena F. Koslover

Throughout physics Brownian dynamics are used to describe the behaviour of molecular systems. When the Brownian particle is confined to a bounded domain, a particularly important question arises around determining how long it takes the…

Optimization and Control · Mathematics 2025-10-24 Jason J. Bramburger

Single-file diffusion is a ubiquitous physical process exploited by living and synthetic systems to exchange molecules with their environment. It is paramount quantifying the escape time needed for single files of particles to exit from…

Soft Condensed Matter · Physics 2016-07-25 Emanuele Locatelli , Matteo Pierno , Fulvio Baldovin , Enzo Orlandini , Yizhou Tan , Stefano Pagliara

What is the path associated with the fastest Brownian particle that reaches a narrow window located on the boundary of a domain? Although the distribution of the fastest arrival times has been well studied in dimension 1, much less is known…

Statistical Mechanics · Physics 2018-05-01 Kanishka Basnayake , Akim Hubl , Zeev Schuss , David Holcman

We study the connection between transport phenomenon and escape rate statistics in two-dimensional standard map. For the purpose of having an open phase space, we let the momentum co-ordinate vary freely and restrict only angle with…

Statistical Mechanics · Physics 2020-10-07 L. Lugosi , T. Kovács

We introduce and investigate the escape problem for random walkers that may eventually die, decay, bleach, or lose activity during their diffusion towards an escape or reactive region on the boundary of a confining domain. In the case of a…

Chemical Physics · Physics 2020-01-03 D. S. Grebenkov , J. -F. Rupprecht

In order to approximate the exit time of a one-dimensional diffusion process, we propose an algorithm based on a random walk. Such an algorithm was already introduced in both the Brownian context and in the Ornstein-Uhlenbeck context. Here…

Probability · Mathematics 2019-12-12 Samuel Herrmann , Nicolas Massin

In genetic circuits, when the mRNA lifetime is short compared to the cell cycle, proteins are produced in geometrically-distributed bursts, which greatly affects the cellular switching dynamics between different metastable phenotypic…

Statistical Mechanics · Physics 2016-05-25 Shay Be'er , Metar Heller-Algazi , Michael Assaf

It is now well established that microswimmers can be sorted or segregated fabricating suitable microfluidic devices or using external fields. A natural question is how these techniques can be employed for dividing swimmers of different…

Statistical Mechanics · Physics 2020-11-04 Matteo Paoluzzi , Luca Angelani , Andrea Puglisi

We study an interacting particle system whose dynamics depends on an interacting random environment. As the number of particles grows large, the transition rate of the particles slows down (perhaps because they share a common resource of…

Probability · Mathematics 2009-02-16 Charles Bordenave , David McDonald , Alexandre Proutiere

Neuronal networks can generate burst events. It remains unclear how to analyse interburst periods and their statistics. We study here the phase-space of a mean-field model, based on synaptic short-term changes, that exhibit burst and…

Statistical Mechanics · Physics 2020-12-17 Lou Zonca , David Holcman

Many physical processes depend on the time it takes a diffusing particle to find a target. Though this classical quantity is now well-understood in various scenarios, little is known if the diffusivity depends on the location of the…

Statistical Mechanics · Physics 2025-12-23 Hwai-Ray Tung , Sean D Lawley

The bounded rationality plays a vital role in the collective behavior of the evacuation process. Also investigating human behavior in such an extreme situation is a continuing concern within social psychology. In this paper, we construct a…

Physics and Society · Physics 2019-06-26 Lingxiao Wang , Yin Jiang

New theorems for the moments of the first passage time of one dimensional nonlinear stochastic processes with an entrance boundary are formulated. This important class of one dimensional stochastic processes results among others from…

Analysis of PDEs · Mathematics 2020-04-22 Leo Dostal , Navaratnam Sri Namachchivaya

The escape dynamics of sticky particles from textured surfaces is poorly understood despite importance to various scientific and technological domains. In this work, we address this challenge by investigating the escape time of adsorbates…

Statistical Mechanics · Physics 2025-07-15 Yuval Scher , Shlomi Reuveni , Denis S. Grebenkov