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We discuss the Surface-Plasmon-Resonance (SPR) technique based on Fourier -Transform - InfraRed (FTIR) spectrometry. We explore the potential of the infrared surface plasmon resonance technique for biological studies in aqueous solutions…

Biological Physics · Physics 2010-02-03 M. Golosovsky , V. Lirtsman , V. Yashunsky , D. Davidov , B. Aroeti

This work presents a high-performance, multilayered surface plasmon resonance (SPR)-based sensor designed to enhance performance parameters in the near-infrared (NIR) region through angular interrogation. The multi-layered sensor consists…

Optics · Physics 2025-11-11 R. Runthala , N. Grover , P. Arora

A mirrored bilayer structure incorporating layers of Graphene and MoS2 is proposed here for Surface Plasmon Resonance (SPR) biosensing and its performance is evaluated numerically. Starting from the basic configuration, the structure with…

Optics · Physics 2020-02-10 Sayeed Shafayet Chowdhury , Syed Mohammad Ashab Uddin

Surface Plasmon Resonance (SPR) offers a powerful tool for label-free and non-invasive characterization of biomolecular interactions. To date, several experimental configurations, based on two fundamental physical phenomena, e.g.,…

Optics · Physics 2022-11-15 Nishant Shukla , Pawan Chetri , Ratan Boruah , Ankur Gogoi , Gazi A Ahmed

Large dynamic index measurement range (n = 1 to n = 1.7) using surface plasmon resonance (SPR) shifts is demonstrated with a ZnSe prism at 632.8 nm, limited by the available high index liquid hosts. In contrast to borosilicate based SPR…

Instrumentation and Detectors · Physics 2015-10-27 John Canning , Jing Qian , Kevin Cook

Surface Plasmon Resonance (SPR) is an important bio-sensing technique for real-time label-free detection. However, it is pivotal to optimize various parameters of the sensor configuration for efficient and highly sensitive sensing. To that…

Biological Physics · Physics 2020-07-20 Ehsan Kabir , Syed Mohammad Ashab Uddin , Sayeed Shafayet Chowdhury

An algorithm based on PLS regression has been developed and optimized for measuring blood glucose level using the infra-red transmission spectrum of blood samples. A set of blood samples were tagged with their glucose concentration using an…

Quantitative Methods · Quantitative Biology 2018-04-11 Afarin Aghassizadeh , Mohammad Reza Nematollahi , Iman Mirzaie , Mehdi Fardmanesh

We show that for the optimized angle of incidence, the SPR based optical sensors exhibit dual resonance in the near-infrared region around which the sensor becomes exceptionally high sensitive. Both the resonances show opposite spectral…

Optics · Physics 2020-07-07 Indrajeet Kumar , Ranjeet Dwivedi , Saurabh Mani Tripathi

Microplastics are pervasive pollutants that pose threats to the environment and human health. Detecting them reliably represents a crucial step toward finding solutions. While traditional techniques like vibrational and mass spectroscopies…

Instrumentation and Detectors · Physics 2025-05-29 Natalia A. Gutierrez Andrade , Yunfeng Nie , Wendy Meulebroeck , Heidi Ottevaere

Biosensors based on the principle of surface plasmon resonance (SPR) detection were used to measure biomolecular interactions in sarcomeres and changes of the dielectric constant of tubulin samples with varying concentration. At SPR,…

Quantum Physics · Physics 2015-06-26 Hans A. Schuessler , Alexander A. Kolomenskii , Andreas Mershin , D. V. Nanopoulos

In this paper we report a fiber optical sensor system based on surface plasmon resonance (SPR) with real-time response for biochemical interaction analysis. The fiber sensor is constructed from a multi-mode fiber with plastic cladding. To…

Applied Physics · Physics 2019-05-10 Zhixin Tan , Xuejin Li , Yuzhi Chen , Ping Fan

Surface plasmon resonance (SPR) is generally observed by excitation of surface plasmon polaritons on the metal (Au/Ag) surface. In order to utilize the SPR phenomenon for sensing application, the metal surface is functionalized with…

Optics · Physics 2022-12-20 Amrit Kumar , Manjuladevi V , R. K. Gupta

This paper presents a comprehensive study on a novel multilayer surface plasmon resonance (SPR) biosensor designed for detecting trace-level toxins in liquid samples with exceptional precision and efficiency. Leveraging the Kretschmann…

Systems and Control · Electrical Eng. & Systems 2025-01-31 Suripto Bhuiyan , Michael Geller

Chiral sensitive techniques have been used to probe the fundamental symmetries of the universe, study biomolecular structures, and even develop safe drugs. As chiral signals are inherently weak and often suppressed by large backgrounds,…

Applied Physics · Physics 2019-01-29 Sotiris Droulias , Lykourgos Bougas

Plasmonic sensing in the infrared region employs the direct interaction of the vibrational fingerprints of molecules with the plasmonic resonances, creating surface-enhanced sensing platforms that are superior than the traditional…

Infrared (IR) spectroscopy has emerged as a pivotal tool in biomedical diagnostics, offering label-free spectral biomarkers for the detection of numerous diseases, particularly in the fingerprint region. However, the lack of rapid and…

Optics · Physics 2026-01-12 Xiangyu Zhao , Yuqing Liu , Jingzhu Shao , Longsheng Fang , Chongzhao Wu

Plasmonic sensing is an established technology for real-time biomedical diagnostics and air-quality monitoring. While intensity and wavelength tracking are the most commonly used interrogation methods for Surface Plasmon Resonance (SPR),…

Photothermal-Induced Resonance (PTIR) spectroscopy and imaging with infrared light has seen increasing application in molecular spectroscopy of biological samples. The appeal of the technique lies in its capability to provide information…

Quantitative Methods · Quantitative Biology 2019-11-19 Luca Quaroni

Hyperspectral microscopy is an imaging technique that provides spectroscopic information with high spatial resolution. When applied in the relevant wavelength region, such as in the infrared (IR), it can reveal a rich spectral fingerprint…

Fourier-transform infrared spectroscopy (FTIR) is a powerful analytical method for not only the chemical identification of solid, liquid, and gas species, but also the quantification of their concentration. However, the chemical…

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